Results 161 to 170 of about 112,000 (305)

Oral Health and Idiopathic Female Infertility: A Potential Association. [PDF]

Oral Health Prev Dent
Kovács D, Boda K, Badó A, Gorzó I, Pásztor N, Radnai M.   +5 more
europepmc   +1 more source

Cuproptosis and Mitophagy Mediated by the THUMPD1/IGF2R‐Dependent Suppression of AKT and Activation of AMPK Signaling Suppress Lung Adenocarcinoma Progression

Advanced Science, EarlyView.
THUMPD1 drives a tumor‐suppressive signaling cascade in lung adenocarcinoma by promoting IGF2R expression. IGF2R associates with PPP2R1A to suppress AKT and activate AMPK, leading to SLC31A1 upregulation and copper accumulation. Elevated copper disrupts mitochondrial metabolism and induces excessive mitophagy, thereby restraining tumor growth and ...
Kai Wu, Bo Qin, Zhuoyu Gu, Weizheng Ding, Xiaoming Chen, Kaishang Zhang, Yujin Qiao, Shuang Yuan, Song Zhao, Xiangnan Li, Peng Zhang   +10 more
wiley   +1 more source

Female Infertility Treatment with Acupuncture

, 2009
Infertility currently affects about 6.1 million women in the USA.  Although in vitro fertilization (IVF) has been routinely used for female infertility, the average success rate is lower than 30% (American Pregnancy Association). The encouraging news for
Yao, MD, Ping
core  

An observational study on causes of female infertility

Background: Infertility is characterized by the inability to conceive after 12 months or more of consistent, unprotected sexual activity. It can be caused by a variety of abnormalities of the female reproductive system.
Parunandi, Yashaswini, Thatipelli, Ravi Chander, Anitha, Adaboina, Nousheen, Syed, Shenkeshi, Suvarchala, Fathima, Hijazi   +5 more
core   +1 more source

A Homozygous Frameshift Mutation in <i>GREB1</i> Leads to Female Infertility. [PDF]

Hum Mutat
Yang J, Yang L, Yan B, Li H, Zhang L, Hu T, Chao X, Zhang C, Ni Y, Wang Z.   +9 more
europepmc   +1 more source

Single‐Cell Dissection of Tumor‐Infiltrating Lymphocytes Reveals Cellular Architecture Predictive of Therapeutic Efficacy in Acral Melanoma

Advanced Science, EarlyView.
Autologous tumor‐infiltrating lymphocyte (TIL) therapy shows promising efficacy in acral melanoma, yet determinants of durable response remain unclear. By integrating single‐cell transcriptomics and TCR sequencing, this study reveals that TIL products enriched for T follicular helper and intermediate exhausted T cells establish persistent clonal ...
Chao Zhang, Wanyi Xiao, Hongru Shen, Fenge Li, Ting Li, Weihong Zhang, Haotian Liu, Ziwei Gao, Hongyu Wang, Xiubao Ren, Kexin Chen, Xiangchun Li, Jilong Yang   +12 more
wiley   +1 more source

Diagnostic markers of human female infertility

, 2012
The subject invention pertains to methods and reagents for the diagnosis of female infertility, prognostic indicators for female infertility, compounds for the treatment of female infertility, compounds and methods for contraception.
Kothapalli, Ravi, Tabibzadeh, Siamak
core  

Nutritional Regulation of Ovarian Bioenergetics: Implications for Reproductive Aging and Female Infertility. [PDF]

Nutrients
Kim J, Lee J.
europepmc   +1 more source

Vorinostat Potentiates Chemoimmunotherapy in Immune‐Enriched Pancreatic Cancer

Advanced Science, EarlyView.
Immune‐enriched pancreatic cancer does not confer a significant survival advantage. SAHA sensitizes these “hot” tumors to chemoimmunotherapy by disrupting a FASN/PARP9‐driven “metabolic trap” and enhancing CD8+ T cell function. A CD8high/FASNhigh/PARP9high signature identifies patients who are most likely to benefit from the “gemcitabine‐nivolumab‐SAHA”
Chen Chen, Dingru Li, Yingna Liao, Zehua Wang, Chunbin Zhu, Zifeng Zhang, Liquan Jin, Yueyue Chen, Jiaoshun Chen, Junyi Xu, Miaoyan Wei, Rong Tang, Xianjun Yu, Si Shi   +13 more
wiley   +1 more source

Unveiling the Bidirectional Relationship on the Effect of Gut Microbiota and Female Infertility: A Narrative Review. [PDF]

Health Sci Rep
Balagoni S, Evelyne DG, Mathews A, Dugyala RR, Biradar M, Deekshith V, Goel A, Verma A.   +7 more
europepmc   +1 more source