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Fertility Preservation [PDF]

memo - Magazine of European Medical Oncology, 2020
Most of men with non-mosaic Klinefelter syndrome (KS) are azoospermic and for many decades use of donor semen was the only possible way of becoming a father for KS men. In the last 20 years, hundreds of non-mosaic azoospermic KS men have been submitted to testicular sperm extraction (TESE) and an overall sperm retrieval rate (SRR) of approximately
Barbonetti A., D'Andrea S., Totaro M., Parisi A., Salacone P., Francavilla S.   +5 more
  +8 more sources

Trends and outcomes of fertility preservation in patients presenting with cancer during pregnancy or postpartum—a longitudinal observational cohort study [PDF]

Frontiers in Endocrinology
ObjectiveThe aim of this study was to assess the trends and outcomes of fertility preservation (FP) in women referred for FP counseling and presenting with pregnancy-associated cancer (PAC).MethodThis is a prospective cohort study of all patients ...
Hanna P. Nilsson, Riikka Bornhede, Riikka Bornhede, Anna L. V. Johansson, Kenny A. Rodriguez-Wallberg, Kenny A. Rodriguez-Wallberg   +5 more
doaj   +2 more sources

Fertility Preservation [PDF]

Mayo Clinic Proceedings, 2011
Of the estimated 1.5 million men and women who were diagnosed as having cancer in 2010, approximately 10% are younger than 45 years. For these individuals, cancer treatment can be lifesaving but can permanently affect reproductive capacity. The American Society of Clinical Oncology has recommended that oncologists discuss the possibility of infertility
Pasquale Patrizio, A. L. Caplan
openaire   +3 more sources

Human Sperm Morphology as a Marker of Its Nuclear Quality and Epigenetic Pattern

Cells, 2022
Background: Human sperm chromatin condensation is a sum of epigenetic events that allows for the near-complete replacement of histones with protamines.
Marion Bendayan, Liliana Caceres, Emine Saïs, Nelly Swierkowski-Blanchard, Laura Alter, Amélie Bonnet-Garnier, Florence Boitrelle   +6 more
doaj   +1 more source

Is letrozole during ovarian stimulation useful in breast cancer patients undergoing fertility preservation to reduce early luteal progesterone levels following GnRH-agonist trigger?

Reproductive Biology and Endocrinology, 2022
Background In absence of contraindication, breast cancer patients of reproductive age can undergo fertility preservation with controlled ovarian stimulation for oocyte/embryo cryopreservation before the administration of potentially gonadotoxic ...
Imane Lalami, Julie Labrosse, Isabelle Cedrin-Durnerin, Marjorie Comtet, Claire Vinolas, Fabien Krief, Christophe Sifer, Maeliss Peigne, Michael Grynberg   +8 more
doaj   +1 more source

The Late Effects of Cancer Treatment on Female Fertility and the Current Status of Fertility Preservation—A Narrative Review

Life, 2023
Fertility counseling should be offered to all individuals of young reproductive age early in the patient’s trajectory following a cancer diagnosis. Systemic cancer treatment and radiotherapy often have an inherent gonadotoxic effect with the potential to
Kenny A. Rodriguez-Wallberg, Yanyu Jiang, Tobias Lekberg, Hanna P. Nilsson   +3 more
doaj   +1 more source

A fertile future: Fertility preservation special series [PDF]

Reproduction and Fertility, 2022
Lay summary Fertility preservation is a rapidly advancing field with numerous broad applications ranging from retaining the prospect of fertility in a child with cancer to protecting an entire species from extinction. In recent years, huge strides have been made in understanding the biology of male and female reproduction in animals and humans and ...
Mitchell, RT, Williams, SA
openaire   +3 more sources

Human umbilical cord-derived mesenchymal stem cells (hUC-MSCs) alleviate excessive autophagy of ovarian granular cells through VEGFA/PI3K/AKT/mTOR pathway in premature ovarian failure rat model

Journal of Ovarian Research, 2023
Background Premature ovarian failure (POF) is one of the leading causes of female infertility and is accompanied by abnormal endocrine, seriously affecting female quality of life.
Wenjie Dai, Hong Yang, Bo Xu, Tiantian He, Ling Liu, Xiaoqian Ma, Jiaxue Ma, Guoqin Yang, Rui Si, Xiuying Pei, Xing Du, Xufeng Fu   +11 more
doaj   +1 more source

Metformin improves polycystic ovary syndrome in mice by inhibiting ovarian ferroptosis

Frontiers in Endocrinology, 2023
Background and objectivePCOS is a common metabolic disorder in women of reproductive age, which pathogenesis is very complex. The role of ferroptosis in PCOS is a novel finding, and the mechanistic studies are not clear. Metformin is a commonly used drug
Qingjie Peng, Xiaojiang Chen, Xiaoxia Liang, Jiahui Ouyang, Qiangqiang Wang, Shuai Ren, Haibo Xie, Chunhong Wang, Yaqun Sun, Xin Wu, Hetao Liu, Changchun Hei, Miao Sun, Qing Chang, Xinrui Liu, Guangyong Li, Guangyong Li, Rui He   +17 more
doaj   +1 more source

For patients with non-obstructive azoospermia, the outcome of testicular sperm extraction correlates with self-esteem, sexual health and the quality of the couple’s relationship

Basic and Clinical Andrology, 2022
Resume Introduction Quelques études concernant l’azoospermie ou les résultats négatifs de l’extraction de sperme testiculaire (TESE) montrent que ces résultats peuvent être liés à la dépression ou aux dysfonctions érectiles.
Marion BENDAYAN, Emine SAIS, Laura ALTER, Khadija FATHALLAH, Monique JAOUL, Pierre Olivier BOSSET, Geoffroy ROBIN, Florence BOITRELLE   +7 more
doaj   +1 more source