Results 11 to 20 of about 955,198 (296)

Metformin improves polycystic ovary syndrome in mice by inhibiting ovarian ferroptosis

Frontiers in Endocrinology, 2023
Background and objectivePCOS is a common metabolic disorder in women of reproductive age, which pathogenesis is very complex. The role of ferroptosis in PCOS is a novel finding, and the mechanistic studies are not clear. Metformin is a commonly used drug
Qingjie Peng, Xiaojiang Chen, Xiaoxia Liang, Jiahui Ouyang, Qiangqiang Wang, Shuai Ren, Haibo Xie, Chunhong Wang, Yaqun Sun, Xin Wu, Hetao Liu, Changchun Hei, Miao Sun, Qing Chang, Xinrui Liu, Guangyong Li, Guangyong Li, Rui He   +17 more
doaj   +1 more source

For patients with non-obstructive azoospermia, the outcome of testicular sperm extraction correlates with self-esteem, sexual health and the quality of the couple’s relationship

Basic and Clinical Andrology, 2022
Resume Introduction Quelques études concernant l’azoospermie ou les résultats négatifs de l’extraction de sperme testiculaire (TESE) montrent que ces résultats peuvent être liés à la dépression ou aux dysfonctions érectiles.
Marion BENDAYAN, Emine SAIS, Laura ALTER, Khadija FATHALLAH, Monique JAOUL, Pierre Olivier BOSSET, Geoffroy ROBIN, Florence BOITRELLE   +7 more
doaj   +1 more source

High-Survival Rate After Microinjection of Mouse Oocytes and Early Embryos With mRNA by Combining a Tip Pipette and Piezoelectric-Assisted Micromanipulator

Frontiers in Cell and Developmental Biology, 2021
Utilizing microinjection to introduce biological molecules such as DNA, mRNA, siRNA, and proteins into the cell is well established to study oocyte maturation and early embryo development in vitro. However, microinjection is an empirical technology.
Lei-Ning Chen, Lei-Ning Chen, Xiao-Yan Fan, Xiao-Yan Fan, Yi-Tong Liu, Shao-Qing Chen, Feng-Yun Xie, Feng-Yun Xie, Li Zeng, Juan Wen, Jin Li, Jun-Yu Ma, Jun-Yu Ma, Xiang-Hong Ou, Xiang-Hong Ou, Shi-Ming Luo, Shi-Ming Luo, Lei Guo, Lei Guo   +18 more
doaj   +1 more source

SIRT 3 was involved in Lycium barbarum seed oil protection testis from oxidative stress: in vitro and in vivo analyses

Pharmaceutical Biology, 2021
Context Lycium barbarum L. (Solanaceae) seed oil (LBSO) exerts LBSO exerts protective effects in the testis in vivo and in vitro via upregulating SIRT3.
Zhang-Jie Yang, Yu-Xin Wang, Shuai Zhao, Na Hu, Dong-Mei Chen, Hui-Ming Ma   +5 more
doaj   +1 more source

Freezing the Biological Clock: A Viable Fertility Preservation Option for Young Singaporean Women? [PDF]

, 2013
In March 2012, an article in The Straits Times entitled ‘Freezing eggs could reverse falling birth rate’ suggested that employing the latest oocyte cryopreservation techniques could both foster individual women’s reproductive autonomy and impact ...
Lee, Geok Ling, Blyth, E., Yee, Samantha, Blyth, Eric, Yee, S., Lee, G.L.   +5 more
core   +3 more sources

Effect of e-cigarette refill liquid on follicular development and estrogen secretion in rats

Tobacco Induced Diseases, 2022
Introduction Electronic cigarettes (e-cigarettes) have recently become popular as an alternative to conventional cigarettes. The aim of this study is to investigate the effects of e-cigarette refill liquid (e-liquid) on follicular development and ...
Tairen Chen, Mengjing Wu, Yuting Dong, Bin Kong, Yufang Cai, Changchun Hei, Kai Wu, Chengjun Zhao, Qing Chang   +8 more
doaj   +1 more source

Roles of follicle stimulating hormone and sphingosine 1-phosphate co-administered in the process in mouse ovarian vitrification and transplantation

Journal of Ovarian Research, 2023
Some major challenges of ovarian tissue vitrification and transplantation include follicle apoptosis induced by cryopreservation and ischemia-reperfusion injury, as well as ovarian follicle loss during post-transplantation.
Fei Wang, Yuan Tian, Liwen Huang, Tian Qin, Wenye Ma, Chengbin Pei, Bo Xu, Hang Han, Xinrui Liu, Pengge Pan, Xiaoli Yu, Qin Chang, Yanrong Wang, Shuya Zhang, Xiuying Pei   +14 more
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Cancer treatment and gonadal function : experimental and established strategies for fertility preservation in children and young adults [PDF]

, 2015
Copyright © 2015 Elsevier Ltd. All rights reserved.Preservation of gonadal function,is an important priority for the long-term health of cancer survivors of both sexes and all ages at treatment..
Mitchell, Rod T, Anderson, Richard A, Spears, Norah, Wallace, W Hamish B, Kelsey, Thomas W, Telfer, Evelyn E   +5 more
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Fertility Preservation in Hypogonadal Men

, 2022
Fertility preservation among men with secondary hypogonadism is an extensive topic with contemporary regimens emerging. The original approach of testosterone replacement therapy has long been replaced by a variety of therapies as the understanding of the
Cohen, Jordan, Andrew Rezk, Jordan Cohen, Rezk, Andrew, Ramasamy, Ranjith, Ranjith Ramasamy   +5 more
core   +1 more source

Emerging roles of ferroptosis in male reproductive diseases

Cell Death Discovery, 2023
Ferroptosis is a type of programmed cell death mediated by iron-dependent lipid peroxidation that leads to excessive lipid peroxidation in different cells.
Wenzheng Yuan, Zhibin Sun, Guojie Ji, Huanhuan Hu   +3 more
doaj   +1 more source