Current Medical Research Winter 2008–Spring 2009 [PDF]
, 2009 Note that the “Current Medical Research” feature focuses on issues relevant to natural family planning and the beginning of life. This piece is complemented by medical reviews published in The National Catholic Bioethics Quarterly, which focus more on ...
Fehring, Richard
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Fertility preservation in gynaecologic cancers [PDF]
, 2018 Due to substantial improvement in the diagnosis and treatment of gynaecologic cancers, a better understanding of patient care needs to be revised. We reviewed the literature related to fertility preservation strategies in gynaecological cancer and ...
De Felice, Francesca +9 more
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Molecular Oncology, EarlyView.A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira +14 more
wiley +1 more source
A small population of hypothalamic neurons govern fertility: the critical role of VAX1 in GnRH neuron development and fertility maintenance. [PDF]
, 2016 Fertility depends on the correct maturation and function of approximately 800 gonadotropin-releasing hormone (GnRH) neurons in the brain. GnRH neurons are at the apex of the hypothalamic-pituitary-gonadal axis that regulates fertility. In adulthood, GnRH
Hoffmann, Hanne M, Mellon, Pamela L
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Inhibition of CDK9 enhances AML cell death induced by combined venetoclax and azacitidine
Molecular Oncology, EarlyView.The CDK9 inhibitor AZD4573 downregulates c‐MYC and MCL‐1 to induce death of cytarabine (AraC)‐resistant AML cells. This enhances VEN + AZA‐induced cell death significantly more than any combination of two of the three drugs in AraC‐resistant AML cells.
Shuangshuang Wu +18 more
wiley +1 more source
Fertility Preservation in Female Patients with Cancer Part II: Royan Institute Clinical Practice Guideline for Girls and Women with Cancer; A Review Study [PDF]
International Journal of Fertility and SterilityThe fertility preservation (FP) is a paramount concern for oncology patients and should be regarded as an essentialcomponent of their overall cancer management strategy. The magnitude of this issue has been recognized in FPguidelines. The formulation and
Azar Yahyaei +2 more
doaj +1 more source
Sexual and relational satisfaction in couples where the woman has polycystic ovary syndrome: a dyadic analysis [PDF]
, 2014 STUDY QUESTION: How are objective characteristics of polycystic ovary syndrome (PCOS) and PCOS-related concerns associated with the sexual and relational satisfaction of PCOS women and their partners? SUMMARY ANSWER: Both objective PCOS characteristics (
Buysse, Ann +5 more
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Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib
Molecular Oncology, EarlyView.WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute +17 more
wiley +1 more source
Fertility Preservation in Female Patients with Cancer. Part I: Challenges and Future Prospects in Developing Countries; A Narrative Review Study [PDF]
International Journal of Fertility and SterilityWhile international guidelines on oncofertility practice have been published in developed countries, there is limitedinformation available on oncofertility practice in developing countries, which often face limitations in their cancerhealth support ...
Esmat Mashhadi Meighani +2 more
doaj +1 more source
Genetic variants of CYP2C9 and IL-6 on female infertility [PDF]
, 2017 AIM: To study the polymorphic variants in CYP2C9*2*3 and the C-174G promoter polymorphism of the IL-6 gene on Infertile Women.BACKGROUND: - Infertility affects 15–20% of couples worldwide.
Alves, H. +7 more
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