Results 11 to 20 of about 3,037,859 (309)
Cardiotoxicity remains a significant limitation in the clinical application of chemotherapeutic agents, particularly anthracyclines. Doxorubicin (DOX), a widely used representative of this group, exhibits potent antitumor activity and is commonly ...
V. V. Mukvych, O. V. Severynovska
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SEXUAL REINFORCEMENT IN THE FEMALE RAT [PDF]
Sexual reinforcement in the female rat was studied in a preparation that allowed continuous operant responding for access to a male rat leading to intromission. Experiment 1 used a high operant level nose‐poke response to test the possible reinforcing effects of some components of access to a male.
T J, Matthews +5 more
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Diabetogenic Effects of Ochratoxin A in Female Rats [PDF]
In this study, diabetogenic effects of long term Ochratoxin A (OTA) administration in rats were investigated and its role in the etiology of diabetes mellitus (DM) was examined utilizing 42 female Wistar rats for these purposes. The rats were divided into 3 different study and control groups according to the duration of the OTA administration.
Mor, F. +4 more
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SEXUAL MATURATION IN BULBECTOMIZED FEMALE RATS [PDF]
Summary. Vaginal opening was delayed approximately 10 days in rats when olfactory bulbs were removed (bulbectomy) at 6 days of age. No such delay occurred in rats subjected to sham operation at this age or in rats bulbectomized at 20 days of age.
N, Sato +3 more
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ANDROGENIZATION OF THE FEMALE RAT WITH ANDROSTENEDIOL [PDF]
The induction of a persistent vaginal cornification—anovulatory syndrome (androgenization) following steroid treatment of the neonatal female rat has been well documented (reviewed by Johnson, 1972). The exact timing of a `critical period' for the induction of this syndrome has not been determined but, in males, the gonads must be removed within 48 hr ...
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The ontogeny of anxiety-like behavior in rats from adolescence to adulthood [PDF]
Funding provided for Gillian Brown by Wellcome Trust grant 078405/Z/05/ZIn human beings, susceptibility to anxiety disorders can be relatively high during adolescence.
Lynn, Debra Alana, Brown, Gillian Ruth
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Doxycycline reduces osteopenia in female rats [PDF]
AbstractDoxycycline, a member of the tetracycline family, is a drug used as an antibiotic (dosage of 100 mg/day) and as an anti-inflammatory drug on the dosage of 20 mg twice a day, this use has Matrix Metalloproteinases (MMP) inhibitor action. Doxycycline is a calcium chelator and therefore interferes in bone remodeling.
Fellipe A. T. de Figueiredo +5 more
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Ontogeny of sex differences in response to novel objects from adolescence to adulthood in Lister-hooded rats [PDF]
This work was supported by The Wellcome Trust [grant 078405/Z/05/Z]n humans, novelty-seeking behavior peaks in adolescence and is higher in males than females.
Gillian R. Brown +3 more
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The ontogeny of exploratory behavior in male and female adolescent rats (Rattus norvegicus) [PDF]
Supported by Wellcome Trust grant 078405/Z/05/ZDuring adolescence, rats gain independence from their mothers and disperse from the natal burrow, with males typically dispersing further than females. We predicted that, if dispersal patterns are associated
Debra A. Lynn +3 more
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Placentophagia in weanling female laboratory rats [PDF]
ABSTRACTPlacentophagia is common in parturient mammals and offers physiological and behavioral advantages for mothers. In natural environments, weanlings are often present during the birth of younger siblings, but it is unknown if weanling rats are placentophagic or prefer placenta over other substances.
Kaitlyn M. Harding, Joseph S. Lonstein
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