Results 91 to 100 of about 5,508,521 (365)

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

open access: yesFEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee   +7 more
wiley   +1 more source

Behavioral and Cognitive Characteristics of Females and Males With Autism in the Simons Simplex Collection

open access: yesJournal of the American Academy of Child and Adolescent Psychiatry, 2013
Objective To examine differences in behavioral symptoms and cognitive functioning between males and females with autism spectrum disorder (ASD). Method We analyzed data from 2,418 probands with autism (304 females, 2,114 males) included in the Simons ...
T. Frazier   +3 more
semanticscholar   +1 more source

Levels of depression among delinquent females and academically gifted females: treatment implications

open access: yes, 2002
Plan BThis study examines levels of depression between two groups of adolescent females: delinquent females and academically gifted females. The purpose of this study is to determine the difference in levels of depression, as measured by the Beck ...
Hakes, Holly S.
core  

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

No Detectable Fertility Benefit from a Single Additional Mating in Wild Stalk-Eyed Flies

open access: yes, 2010
Background: Multiple mating by female insects is widespread, and the explanation(s) for repeated mating by females has been the subject of much discussion.
Fowler, K   +8 more
core   +1 more source

Cognizance and utilization about breast cancer screening among the health professional female students and staffs of University Kuala Lumpur, Royal College of Medicine Perak, Malaysia

open access: yesIndian Journal of Medical and Paediatric Oncology, 2016
Background: Breast cancer (BC) is a major life-threatening problem and a global concern including Malaysia. BC is an equal threat for both developing and developed countries.
ATM Emdadul Haque   +5 more
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Identity development and body image dissatisfaction in college females [PDF]

open access: yes, 2001
Plan BThe importance of body image dissatisfaction and identity development among women is becoming a significant concern when considering the risk of developing eating disorders.
Chase, Michelle E.
core  

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

open access: yesMolecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge   +17 more
wiley   +1 more source

Social competition and selection in males and females

open access: yesPhilosophical Transactions of the Royal Society B: Biological Sciences, 2013
During the latter half of the last century, evidence of reproductive competition between males and male selection by females led to the development of a stereotypical view of sex differences that characterized males as competitive and aggressive, and ...
T. Clutton‐Brock, É. Huchard
semanticscholar   +1 more source

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