Results 111 to 120 of about 3,608,478 (312)
Supporting Survivor‐Centered Care Through Digital Health Integration
ABSTRACT Survivors of childhood cancer face barriers to receiving guideline‐based, long‐term follow‐up care. Two digital tools, Passport for Care (PFC) and Cancer SurvivorLink (SurvivorLink), address complementary gaps by enabling tailored survivorship care plan (SCP) generation, updating, storage, and sharing.
Jordan G. Marchak +15 more
wiley +1 more source
ABSTRACT Background Neuromyelitis optica spectrum disorder (NMOSD) is a relapsing autoimmune disease of the central nervous system. High‐dose intravenous methylprednisolone (IVMP) is the standard first‐line therapy for acute attacks, although some patients remain refractory.
Wataru Horiguchi +5 more
wiley +1 more source
James HB Im,1 Ronald Chow,2 Olivia W So,2 Robert Wu,2 Andrea S Gershon3 1The Hospital for Sick Children, Toronto, ON, Canada; 2University Health Network, University of Toronto, Toronto, ON, Canada; 3Sunnybrook Health Sciences Centre, University of ...
Im JHB, Chow R, So OW, Wu R, Gershon AS
doaj
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
The purpose of this study was to compare the mechanical properties of a non-cushioned minimalistic shoe and cushioned shoe during walking at 6 and running at 10 and 14 km∙h−1 in habituated female runners.
Paul William Macdermid +2 more
doaj +1 more source
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
Reading Female Readers: The Female Quixote And Female Quixotism
These two novels offer clues to the idea of the reader and to the understanding of the nature of the reading act in the eighteenth-century context. Because they take the fiction they read as models of the world, both protagonists violate emerging rules for reading fiction.
openaire +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
AAA+ protein unfoldases—the Moirai of the proteome
AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley +1 more source
A study on domestic violence against adult and adolescent females in a rural area of West Bengal
Background: Globally, domestic violence against females is common across culture, religion, class and ethnicity. There are various reasons for domestic violence and it might have serious health outcomes.
Sarkar Madhutandra
doaj

