Results 131 to 140 of about 2,432,610 (268)
Molecular Oncology, EarlyView.Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou +4 more
wiley +1 more source
First record of oviparous females of lipaphis erysimi in Saudi Arabia and description its morphs
, 1998 Plant Protection Department, College of Agriculture, King Saud University, P.O.Box 2460, Riyadh 11451, Saudi ArabiaThe apterous oviparous female of Lipaphis erysimi was detected for the first time in Saudi Arabia from Brassica rapa on 2l.l.l990.
Aldryhim, Yousif N.
core
Molecular Oncology, EarlyView.This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic +10 more
wiley +1 more source
Gut microbiota alterations in patients with non‐small‐cell lung cancer undergoing chemoradiotherapy
Molecular Oncology, EarlyView.We investigated the impact of concurrent chemoradiotherapy (CRT) on the gut microbiota in patients with locally advanced non‐small‐cell lung cancer. Overall gut microbiota composition remained largely stable throughout CRT while antibiotic exposure may influence microbial diversity.
Hanne Marte Nymoen +19 more
wiley +1 more source
The Physical Representation of Female Leaders in the Media
, 2017 In the modern area, female leaders are still underrepresented within the highest levels of leadership within business organizations. The largest explanation for this phenomenon is that there is a misalignment in the expectations for CEOs and female ...
Benuska, Kate
core
Entrepreneurial intentions among female senior high school students in Ghana
International Entrepreneurship ReviewObjective: The objective of the article is to understand entrepreneurial intentions among female high school students in Ghana using the theory of planned behaviour. Moreover, it investigates differences based on parental entrepreneurship background and
Kwaku Amofah +4 more
doaj +1 more source
Molecular Oncology, EarlyView.Loss of NAPRT promotes lung tumor initiation and growth through a noncanonical mechanism, independent of its role in NAD+ biosynthesis. Mechanistically, NAPRT depletion activates the mTORC2‐driven AKT/β‐catenin signaling axis to enhance clonogenic and invasive phenotypes. Furthermore, lung‐specific Naprt deletion significantly increases tumor burden in
Myung Joon Oh +11 more
wiley +1 more source
Frequency of Endometriosis on Diagnostic Laparoscopy in Females with Secondary Infertility
Background: For endometriosis, one of the most common chronic diseases encountered in gynecological outdoors, laparoscopy, is considered as a gold-standard diagnostic tool because direct visualization of endometriotic lesions enables the medical ...
Safdar Nadeem Ch +11 more
core +1 more source
Molecular Oncology, EarlyView.In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico +5 more
wiley +1 more source
Molecular Oncology, EarlyView.This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault +12 more
wiley +1 more source