Results 151 to 160 of about 1,407,592 (395)

Repurposing Acebutolol for Osteoporosis Treatment: Insights From Multi‐Omics and Multi‐Modal Data Analysis

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
Overview of a multi‐omics based drug repurposing strategy. The systematic drug repurposing strategy included the following steps: (1) osteoporosis driver signaling networks were identified from multi‐omics data; (2) drug functional modules were obtained using a network fusion approach to integrate drug similarity information; (3) all drugs were ranked ...
Dan‐Yang Liu   +21 more
wiley   +1 more source

Traumatic anterior hip dislocation with associated bilateral femoral fractures in a child: a case report and review of the literature

open access: yesThe Pan African Medical Journal, 2019
Traumatic anterior hip dislocation is rare, because the hip joint is a highly stable joint. It is extremely rare for the anterior hip dislocation with combined bilateral femoral fracture in children.
Zongbing Cao   +4 more
doaj   +1 more source

Candidate gene analysis of femoral neck trabecular and cortical volumetric bone mineral density in older men. [PDF]

open access: yes, 2010
In contrast to conventional dual-energy X-ray absorptiometry, quantitative computed tomography separately measures trabecular and cortical volumetric bone mineral density (vBMD).
Barrett-Connor, Elizabeth   +15 more
core  

The Failure Rate of Internal Fixation Increases With Sagittal Displacement of the Femoral Head: A Retrospective Study

open access: yesHealth Care Science, EarlyView.
This study found that the degree of femoral head sagittal displacement is linked to the risk of internal fixation failure in femoral neck fracture. Measurements of the sagittal tilt angle of the femoral head (STAFH) using CT‐3D imaging showed high reliability (ICC = 0.97, 95% CI: 0.96–0.98). Patients with excessive sagittal displacement (anterior tilt ≥
Lei Shi   +7 more
wiley   +1 more source

Maternal gut microbiota‐derived daidzein prevents osteoporosis in female offspring following prenatal prednisone exposure

open access: yesiMeta, EarlyView.
Prenatal prednisone therapy (PPT)/prenatal prednisone exposure (PPE) induces long bone dysplasia, reduced peak bone mass (PBM), and increased osteoporosis susceptibility in female offspring. Maternal gut microbiota metabolite daidzein (DAI) mediates PPE‐induced osteoporosis susceptibility in female adult offspring.
Chi Ma   +13 more
wiley   +1 more source

Systematic in‐hospital screening and treatment for osteoporosis in a geriatric population with hip fractures

open access: yesJournal of Hospital Medicine, EarlyView.
Abstract Background Low‐trauma fractures of the hip signify osteoporosis and increase the risk of a second fracture. However, screening for secondary osteoporosis and initiating osteoporosis treatment can be challenging in a geriatric population.
Jeppe B. Rosenbæk   +5 more
wiley   +1 more source

Reproducibilty of partial weight bearing [PDF]

open access: yes
Objectives: To find out whether partial weight bearing can be reproduced and retained. Design: In vivo experiment in normal subjects. Intervention: Training for partial weight bearing (25% of body weight) using bathroom scales.
Doyle, J   +4 more
core   +1 more source

Current Landscape of Short‐T2 Imaging Techniques in the Musculoskeletal System: The Past, Present and Future

open access: yesJournal of Magnetic Resonance Imaging, EarlyView.
ABSTRACT Conventional MRI is limited in imaging tissues with short T2 relaxation times, such as bone, ligaments, and cartilage, due to their rapid signal decay. This limitation has spurred the development of specialized MRI techniques designed specifically for short‐T2 tissue imaging.
Pranjal Rai   +3 more
wiley   +1 more source

Positional Challenges of the Anteroposterior Pelvic X‐Ray: Comparison of Imaging Reject Rates Between Trauma Trolley and Table Bucky

open access: yesJournal of Medical Radiation Sciences, EarlyView.
Pelvic radiographs taken on a trauma trolley had a significantly higher reject rate and lower first exposure accuracy compared with those taken on an x‐ray table. Future studies could involve implementing strategies to reduce the reject rate of pelvic radiographs taken on trauma trolleys. ABSTRACT Introduction Pelvic x‐rays can be conducted on a trauma
Sangdon Lee   +4 more
wiley   +1 more source

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