Results 31 to 40 of about 26,898 (195)

Microrna-206 induces hypoxic necrosis of femoral head by inhibiting VEGF/PI3K/AKT signaling pathway

Frontiers in Genetics, 2023
The most common form of non-traumatic necrosis of the femoral head is anoxic necrosis of the femoral head, which is a metabolic disease, mainly involving young and middle-aged people.
Xingjing Wu, Zhoushan Tao, Wenjing Cheng
doaj   +1 more source

Animal Model Standardization for Studying Avascular Necrosis of the Femoral Head in Legg-Calvé-Perthes Disease [PDF]

Revista Brasileira de Ortopedia, 2023
Objective Testing an experimental model for ischemic necrosis of the femoral head in Legg-Calvé-Perthes disease by evaluating gait, imaging and morphohistology. Methods The operation was done in 11 piglets. Necrosis by cerclage in the right femoral neck
Edson Hidenori Miashiro, Luis Francisco Zanella, Guilherme Schiess Cardoso, Gislene dos Santos Silva, Kauana de Angelis, Silvio Henrique Maia de Almeida   +5 more
doaj   +1 more source

AVASCULAR NECROSIS OF THE FEMORAL HEAD [PDF]

The Journal of Bone and Joint Surgery. British volume, 1960
Since the recent publication of studies of the vascular pattern of the proximal femoral epiphysis in man by Tucker (1949), Trueta and Harrison (1953), Judet, Judet, Lagrange and Dunoyer (1955), and Trueta (1957) there has been a renewed interest in the mechanism of capital necrosis after fractures of the femoral neck.
openaire   +2 more sources

Untargeted metabolomics reveals the effect of lovastatin on steroid-induced necrosis of the femoral head in rabbits

Journal of Orthopaedic Surgery and Research, 2020
Purpose Lovastatin is an important medicine and it shows a significant effect against glucocorticoid-induced necrosis of the femoral head. This study aimed to investigate the effect of lovastatin on preventing necrosis of the femoral head of by serum ...
Xiangnan Ren, Zixing Shao, Wu Fan, Zixuan Wang, Kaiyun Chen, Xuefeng Yu   +5 more
doaj   +1 more source

Ultrasound‐Activatable Piezoelectric Hydrogel Reprograms Mitochondrial Epigenetics for Osteoarthritis Therapy via the mTOR/GATD3A Axis

Advanced Science, EarlyView.
An ultrasound‐activatable piezoelectric hydrogel reprograms chondrocyte mitochondrial epigenetics via the mTOR/GATD3A axis, clearing damaged mitochondria and alleviating osteoarthritis progression in both mouse models and human cartilage explants. ABSTRACT The avascular nature of cartilage hinders drug delivery for osteoarthritis (OA) therapy.
Hui Zheng, Pengfei Yan, Peng Liu, Chang Yan, Mengqi Zhao, Zuyong Wang, Chao Ma, Rongkai Zhang, Xi Cui, Swee Hin Teoh   +9 more
wiley   +1 more source

Bioenergetic Materials for Tissue Regeneration: Modulating Metabolism to Promote Cellular Anabolism

Advanced Science, EarlyView.
Bioenergetic materials (BEMs) modulate cellular metabolism to promote tissue regeneration. Their principal mechanisms of action include metabolic substrate supplementation, metabolic enzyme modulation, organelle transfer, electrical current regulation, redox homeostasis modulation, and oxygen tension modulation.
Yuchen He, Yuwen Wang, Jonathan F. Gong, Yiting Lei, Fei Jin, Weihong Zhu, Rocky S. Tuan, Zhong Alan Li   +7 more
wiley   +1 more source

Zoledronic acid for the treatment of pregnancy-associated femoral head necrosis: A case report

Case Reports in Women's Health, 2020
Introduction: The management of pregnancy-associated femoral necrosis is controversial. Conservative management may eventually lead to hip replacement. Case: A 40-year-old woman developed necrosis of the left hip during her first pregnancy.
Estella Musacchio, Leonardo Sartori
doaj   +1 more source

An Adenoviral‐Vectored Tp0326 Vaccine Elicits Robust Functional Antibodies to Prevent Treponema pallidum Dissemination in a Rabbit Model

Advanced Science, EarlyView.
Vaccination promotes cellular infiltration into primary lesions and effectively inhibits T. pallidum dissemination to distal organs. Notably, transfer of lesion tissue from immunized animals fails to establish infection in naive recipients, confirming specific protective immunity.
Yinbo Jiang, Xinyuan Li, Lixia Huang, Xiangcai Zhang, Wujian Ke   +4 more
wiley   +1 more source

Increasing the angle between caudal screw and the transverse plane may aggravate the risk of femoral head necrosis by deteriorating the fixation stability in patients with femoral neck fracture

European Journal of Medical Research
Necrosis of the femoral head is the main complication in femoral neck fracture patients with triangle cannulated screw fixation. Instant postoperative fixation instability is a main reason for the higher risk of femoral head necrosis.
Jian Zhang, Shengyu Wan, Xiaozhong Luo, Caidong Zhang, Chao Wu, Lipeng He, Jingchi Li   +6 more
doaj   +1 more source

Hip Arthroscopy in Adults Aged 40 or Older Produces Clinically Meaningful Symptom Improvement but Carries a Substantial Risk of Conversion to Total Hip Arthroplasty: A Systematic Review

Arthroscopy, EarlyView.
Purpose To report conversion rates to total hip arthroplasty (THA), patient‐reported outcome measures, and complication rates in adults aged ≥ 40 years undergoing hip arthroscopy since 2016. Methods MEDLINE, EMBASE, and PubMed were searched from January 2016 to March 2025, and pertinent data were abstracted from eligible studies according to the ...
Helena Son, Benjamin Blackman, Joshua Dworsky‐Fried, Dan Cohen, Yoan Bourgeault‐Gagnon, Axel Öhlin, Nicole Simunovic, Iqbal Multani, Tyler M. Hauer, Craig S. Mauro, Olufemi Ayeni   +10 more
wiley   +1 more source