Results 51 to 60 of about 26,898 (195)

Progress in bone tissue engineering biomaterials: Development, challenges, and prospects

VIEW, EarlyView.
Scheme 1 Application of biomaterials in immunomodulation during bone tissue engineering. Abstract Bone defect repair remains a major clinical challenge in orthopedics. Over 2 million cases caused by trauma, tumors, and other factors occur annually, with large‐scale defects posing a particular bottleneck due to limited self‐healing capacity.
Yuanbin Zhang, Junlei Chai, Quanwei Ding, Luping Liu, Kejie Zhang, Jie Lin, Jianhua Zhang, Youju Huang   +7 more
wiley   +1 more source

Novel and emerging cutaneous soft tissue tumours

Histopathology, EarlyView.
This review outlines the defining histopathological, immunophenotypic and molecular features of novel and emerging cutaneous soft tissue tumours, including hybrid superficial ALK‐rearranged myxoid spindle cell neoplasm/epithelioid fibrous histiocytoma, superficial neurocristic tumour, ALK‐rearranged epithelioid vascular neoplasm and MITF pathway ...
Saba Shafi, Josephine K Dermawan
wiley   +1 more source

Harnessing the Therapeutic Potential of Cell Secretomes and Extracellular Vesicles for Craniofacial Regenerative Applications

Journal of Periodontal Research, EarlyView.
The scoping review summarizes the current preclinical and clinical evidence for the use of “cell‐free” therapies in craniofacial (periodontal, bone and soft‐tissue) regeneration. It also aims to highlight key challenges and strategies towards the clinical translation of these therapies.
Siddharth Shanbhag, Magdalena Mayol, Danijel Domic, Madhusudhan Reddy Bobbili, Johannes Grillari, Mariano Sanz, Reinhard Gruber   +6 more
wiley   +1 more source

Clinical Experience With Eliglustat in Children With Gaucher Disease Type 1

American Journal of Medical Genetics Part A, EarlyView.
Erika R. Vucko, Allegra Quadri, Rachel E. Hickey, Carly A. Rasmussen, Monika Izdebski, Joel Charrow, Carlos E. Prada   +6 more
wiley   +1 more source

Treatment Trade‐Offs and Choices for Femoral Fractures: A Systematic Review and Meta‐Analysis

Orthopaedic Surgery, Volume 17, Issue 5, Page 1298-1313, May 2025.
This review examines the trade‐offs between surgical intervention and traction therapy for adult and elderly patients with femoral fractures and surgical contraindications, particularly in resource‐limited settings. While intramedullary nailing may offer better clinical outcomes, traction therapy is often preferred due to limited surgical resources ...
Jiarui Li, Zhu Guo, Tianrui Wang, Kunyue Xing, Wenzhuo Wang, Yaowei Liu, Jiyao Xing, Hongfei Xiang, Jingdong Wang, Bohua Chen, Dongming Xing, Xiaolin Wu   +11 more
wiley   +1 more source

A Criterion of Reduction Quality of Femoral Neck Fractures Based on Spatial Residual Displacements of Femoral Head

Orthopaedic Surgery, Volume 17, Issue 5, Page 1503-1512, May 2025.
The new reduction criterion of reduction quality was based on two indicators of residual displacements: the postoperative residual displacement of the center of the femoral head and the postoperative residual rotational displacement. When the postoperative residual displacement of the center of the femoral head is ≤ 10.22 mm, and the postoperative ...
Shuang‐Shuang Cui, Li‐Kun Zhao, Jing‐Bo Yu, Jian‐Xiong Ma, Xin‐Long Ma   +4 more
wiley   +1 more source

Customized Metal 3D Printed Total Wrist Prosthesis in the Treatment of Severely Destroyed Wrist: Design Rationale and Clinical Applications

Orthopaedic Surgery, Volume 17, Issue 5, Page 1536-1546, May 2025.
Four patients with severe wrist destruction from various causes were treated with customized 3D‐printed prostheses. In addition to the specific articular surface matching their original radiocarpal joint, two innovative proximal component designs were created to address different bone defects.
Qipei Wei, Chang Liu, Shanlin Chen, Min Liu   +3 more
wiley   +1 more source

Comparative Efficacy of Bone Defect Filler Strategies Following Lesion Debridement for Osteonecrosis of the Femoral Head: A Systematic Review and Network Meta‐Analysis

Orthopaedic Surgery, EarlyView.
After screening 2046 records, 18 eligible studies were included, comprising 10 RCTs and 8 NCTs, with a total of 1176 patients and 1284 hips. Fourteen filler strategies were analyzed. ABSTRACT Objective This study aimed to systematically review and compare the clinical and radiographic outcomes of different bone defect filler materials following lesion ...
Zukang Miao, Zhiwei Pei, Bing Wang, Zemeng Hou, Jingkun Jia, Junfei Zhao, Jing Dai, Xiaolei Sun, Xinlong Ma   +8 more
wiley   +1 more source

Outcomes of Femoral Neck Fractures Treated with Cannulated Internal Fixation in Elderly Patients: A Long‐Term Follow‐Up Study

Orthopaedic Surgery, 2020
Objectives To evaluate the long‐term efficacy of cannulated internal fixation in patients who sustain femoral neck fracture (FNF) and risk factors influencing the outcomes.
Fa‐xin Ju, Rui‐xing Hou, Jin Xiong, Hong‐fei Shi, Yi‐xin Chen, Jun‐fei Wang   +5 more
doaj   +1 more source

Effect of Duloxetine on the Perioperative Anxiety Status and Stress Response Following Total Hip Arthroplasty: A Randomized Controlled Trial

Orthopaedic Surgery, EarlyView.
The perioperative administration of duloxetine alleviated anxiety, reduced the stress response and postoperative walking pain, and improved the quality of functional recovery and satisfaction in patients undergoing THA. ABSTRACT Objective The impact of psychological factors on surgical stress response has garnered extensive attention.
Bohua Li, Manxue Zhang, Qianhao Li, Lijun Cai, Liyile Chen, Xiaobing Pu, Pengde Kang   +6 more
wiley   +1 more source