Results 11 to 20 of about 145,425 (362)

Risk of osteoporosis in testicular germ cell tumour survivors: A systematic review of the literature

BJUI Compass, Volume 4, Issue 1, Page 24-43, January 2023., 2023
Abstract Context Testicular germ cell tumour (TGCT) survivors are potentially at risk of developing osteoporosis, because of increased risk for disturbed bone remodelling associated with hypogonadism and anti‐cancer treatment. A number of studies show bone loss and increased fracture risk in TGCT survivors, but data are scarce.
Josephina P. M. Vrouwe, Pauline M. L. Hennus, Neveen A. T. Hamdy, Susanne Osanto, Peter‐Paul M. Willemse   +4 more
wiley   +1 more source

Subtrochanteric fracture after femoral neck system of femoral neck fractures: a report of four cases

BMC Musculoskeletal Disorders, 2023
Background The femoral neck system (FNS) is commonly used for internal fixation of femoral neck fractures and has shown promising results. However, we have observed cases of peri-implant subtrochanteric femur fractures associated with the use of FNS at ...
John C. Fisher, Christopher Gerzina, Kaitlin Rush, Cyrus Caroom   +3 more
doaj   +1 more source

Regional medical inter-institutional cooperation in medical provider network constructed using patient claims data from Japan [PDF]

PLoS ONE 17, 8 (2022) e0266211, 2022
The aging world population requires a sustainable and high-quality healthcare system. To examine the efficiency of medical cooperation, medical provider and physician networks were constructed using patient claims data. Previous studies have shown that these networks contain information on medical cooperation.
arxiv   +1 more source

ENPP1 deficiency: A clinical update on the relevance of individual variants using a locus‐specific patient database

Human Mutation, Volume 43, Issue 12, Page 1673-1705, December 2022., 2022
Abstract Loss‐of‐function variants in the ectonucleotide pyrophosphatase/phosphodiesterase family member 1 (ENPP1) cause ENPP1 Deficiency, a rare disorder characterized by pathological calcification, neointimal proliferation, and impaired bone mineralization. The consequence of ENPP1 Deficiency is a broad range of age dependent symptoms and morbidities
Stephanie A. Mercurio, Lauren M. Chunn, Gus Khursigara, Catherine Nester, Kathleen Wray, Ulrike Botschen, Mark J. Kiel, Frank Rutsch, Carlos R. Ferreira   +8 more
wiley   +1 more source

Longitudinal Change in Bone Density, Geometry, and Estimated Bone Strength in Older Men and Women From The Gambia: Findings From the Gambian Bone and Muscle Aging Study (GamBAS)

Journal of Bone and Mineral Research, Volume 38, Issue 1, Page 48-58, January 2023., 2023
ABSTRACT Musculoskeletal aging in the most resource‐limited countries has not been quantified, and longitudinal data are urgently needed to inform policy. The aim of this prospective study was to describe musculoskeletal aging in Gambian adults. A total of 488 participants were recruited stratified by sex and 5‐year age band (aged 40 years and older ...
Mícheál Ó Breasail, Camille Pearse, Ayse Zengin, Landing Jarjou, Cyrus Cooper, Peter R Ebeling, Ann Prentice, Kate A Ward   +7 more
wiley   +1 more source

Osteocyte Estrogen Receptor β (Ot‐ERβ) Regulates Bone Turnover and Skeletal Adaptive Response to Mechanical Loading Differently in Male and Female Growing and Adult Mice

Journal of Bone and Mineral Research, Volume 38, Issue 1, Page 186-197, January 2023., 2023
ABSTRACT Age‐related bone loss is a failure of balanced bone turnover and diminished skeletal mechanoadaptation. Estrogen receptors, ERα and ERβ, play critical roles in osteoprotective regulation activated by estrogen and mechanical signals. Previous studies mainly focused on ERα and showed that osteocyte‐ERα (Ot‐ERα) regulated trabecular, but not ...
Xiaoyu Xu, Haisheng Yang, Whitney A. Bullock, Maxim A. Gallant, Claes Ohlsson, Teresita M. Bellido, Russell P. Main   +6 more
wiley   +1 more source

Reduced Bone Mass and Increased Osteocyte Tartrate‐Resistant Acid Phosphatase (TRAP) Activity, But Not Low Mineralized Matrix Around Osteocyte Lacunae, Are Restored After Recovery From Exogenous Hyperthyroidism in Male Mice

Journal of Bone and Mineral Research, Volume 38, Issue 1, Page 131-143, January 2023., 2023
ABSTRACT Hyperthyroidism causes secondary osteoporosis through favoring bone resorption over bone formation, leading to bone loss with elevated bone fragility. Osteocytes that reside within lacunae inside the mineralized bone matrix orchestrate the process of bone remodeling and can themselves actively resorb bone upon certain stimuli.
Eva Maria Wölfel, Franziska Lademann, Haniyeh Hemmatian, Stéphane Blouin, Phaedra Messmer, Lorenz C. Hofbauer, Björn Busse, Martina Rauner, Katharina Jähn‐Rickert, Elena Tsourdi   +9 more
wiley   +1 more source

Comparison of Early Clinical Results for Femoral Neck System and Cannulated Screws in the Treatment of Unstable Femoral Neck Fractures

Orthopaedic Surgery, 2020
To compare early clinical effects of the femoral neck system (FNS) and three cannulated screws for the treatment of patients with unstable femoral neck fractures.
Xiao-Qiang Zhou, Zhiqiang Li, Renjie Xu, Yuanshi She, Xiang-xin Zhang, Guangxiang Chen, Xiao Yu   +6 more
semanticscholar   +1 more source

Globular structure of the hypermineralized tissue in human femoral neck [PDF]

Journal of Structural Biology,Volume 212, Issue 2, 1 November 2020, 107606, 2020
Bone becomes more fragile with ageing. Among many structural changes, a thin layer of highly mineralized and brittle tissue covers part of the external surface of the thin femoral neck cortex in older people and has been proposed to increase hip fragility. However, there have been very limited reports on this hypermineralized tissue in the femoral neck,
arxiv   +1 more source

Lipopolysaccharide‐Induced Bone Loss in Rodent Models: A Systematic Review and Meta‐Analysis

Journal of Bone and Mineral Research, Volume 38, Issue 1, Page 198-213, January 2023., 2023
ABSTRACT Osteoporosis has traditionally been characterized by underlying endocrine mechanisms, though evidence indicates a role of inflammation in its pathophysiology. Lipopolysaccharide (LPS), a component of gram‐negative bacteria that reside in the intestines, can be released into circulation and stimulate the immune system, upregulating bone ...
Kirsten N. Bott, Evelyn Feldman, Russell J. de Souza, Elena M. Comelli, Panagiota Klentrou, Sandra J. Peters, Wendy E. Ward   +6 more
wiley   +1 more source