Results 111 to 120 of about 83,212 (276)

Application of robot navigation system for insertion of femoral neck system in the treatment of femoral neck fracture

BMC Musculoskeletal Disorders
Abstract Purpose To evaluate the short-term clinical efficacy and advantages of surgery robot positioning system for insertion of Femoral Neck System (FNS) in the treatment of femoral neck fractures. Methods The clinical data of 52 patients with Femoral neck fracture (FNF ...
Gang Liu, Chengzhi Yang, Renchong Wang, Jingli Tang, Hao Wu, Lu Wei, Juzheng Hu   +6 more
openaire   +3 more sources

Trained Memory of Uterine Macrophages Improves Subsequent Pregnancy Outcomes

Advanced Science, EarlyView.
This study identifies that pregnancy imprints a durable, pregnancy‐specific form of trained immune memory in uterine macrophages, marked by the emergence of LILRB3+/PIR‐B+ cells that expand across gestations, acquire a tolerogenic and metabolically rewired phenotype, and actively protect against inflammatory pregnancy loss in mice.
Jing Wang, Ning Lu, Xin‐Xiu Lin, Xu‐Hui Fang, Yi‐Hui Li, Qing‐Peng Luo, Yu‐Ting Peng, Gil Mor, Ai‐Hua Liao   +8 more
wiley   +1 more source

Prmt6 Deficiency or Inhibition Restores Microglial Homeostasis and Promotes Scar‐Limited Repair in Adult Spinal Cord Injury

Advanced Science, EarlyView.
After spinal cord injury, adult microglia remain persistently activated with chronic PRMT6 (protein arginine methyltransferase 6) upregulation. Prmt6 deficiency or inhibition reestablishes microglial homeostasis and promotes a scar‐limited repairment, enhancing axonal regrowth.
Weilin Peng, Zhengqiang Wu, Yu Xiong, Zhongya Gao, Yishan Liu, Ziyi Wang, Haibin Wang, Chaofeng Han, Wenxiang Chu, Xuhua Lu   +9 more
wiley   +1 more source

A finite element analysis of a low-profile femoral neck system of screws in sleeves in a vertical femoral neck fracture model

BMC Musculoskeletal Disorders
Background Femoral neck system (FNS) has exhibited some drawbacks, such as non-fit of the plate with the lateral femoral cortex, postoperative pain, and the potential risk of subtrochanteric fractures.
Jun Sun, Le Wu, Nan Fang, Wenze Qiao, Lifeng Liu   +4 more
doaj   +1 more source

Targeting Endogenous Lipophagy: A Novel Strategy to Enhance MSC Osteogenesis and Mineralization for Senile Osteoporosis Therapy

Advanced Science, EarlyView.
Schematic representation of the role of lipophagy in bone mesenchymal stem cells(MSCs). In healthy MSCs, functional lipophagy efficiently degrades lipid droplets to support oxidative phosphorylation and cellular energy production, thereby facilitating osteogenic differentiation and matrix mineralization.
Chaoqiang Chen, Zhidong Liu, Yanhang Sun, Xiaojun Xu, Zhexiao Lan, Junhao Zhao, Peitao Xu, Guiwen Ye, Jinteng Li   +8 more
wiley   +1 more source

Length-stable fixation reduces femoral neck shortening in unstable femoral neck fractures: A retrospective comparative study of length-stable dynamic hip screw versus femoral neck system fixation

Journal of Orthopaedic Surgery
Background Femoral neck shortening following internal fixation of unstable femoral neck fractures can compromise functional recovery, particularly in young, active patients.
Seonghyun Kang, Wonseok Choi, Jeong Seok Choi, Eic Ju Lim, SungJin Ahn, Jong-Keon Oh, William T. Kent, Whee Sung Son, Jae-Woo Cho   +8 more
doaj   +1 more source

Total posterior leg open wound management with free anterolateral thigh flap: case and literature review. [PDF]

, 2013
Soft tissue coverage of the exposed Achilles tendon is a unique reconstructive challenge. In this report, we describe the management of a large posterior leg wound with exposed Achilles tendon using a free anterolateral thigh (ALT) flap. A careful review
Chou, Stephanie, Osman, Soleiman, Rosing, James, Sahar, David E   +3 more
core   +1 more source

Positive impact of low-dose, high-energy radiation on bone in partial- and/or full-weightbearing mice [PDF]

, 2019
Astronauts traveling beyond low Earth orbit will be exposed to galactic cosmic radiation (GCR); understanding how high energy ionizing radiation modifies the bone response to mechanical unloading is important to assuring crew health. To investigate this,
Allen, Matthew R., Black, Jeremy M., Bloomfield, Susan A., Bokhari, Rihana S., Boudreaux, Ramon D., Braby, Leslie A., Franklin, Katherine A., Hogan, Harry A., Macias, Brandon R., Metzger, Corinne E.   +9 more
core   +1 more source

CD44‐Targeting Hydroxyapatite Nanoparticles (HAP) Induce Mitochondrial Dysfunction‐Driven PANoptosis and Immunogenic Cell Death (ICD) via Ca Overload in Colorectal Cancer

Advanced Science, EarlyView.
ABSTRACT Colorectal cancer (CRC) remains therapeutically challenging due to high metastasis, recurrence, and immunotherapy resistance driven by tumor microenvironment‐mediated immune evasion. Immunogenic cell death (ICD) offers a promising strategy to reshape the immune microenvironment, yet existing ICD inducers suffer from poor targeting efficiency ...
Yao Xiao, Yuxuan Yang, Haosen Qiu, Jia Yang, Hao Liang, Zhaojun Jiang, Xiao Tong, Yongying Li, Qunfeng Huang, Jiaming Wu, Tian Lin, Jiang Yu, Min Liang   +12 more
wiley   +1 more source

Wireless blood pressure sensor implantation in sheep: A detailed technique

Animal Models and Experimental Medicine, EarlyView.
Twelve adult sheep underwent wireless blood pressure sensor implantation. The procedure lasted an average of 36 min, with mean systolic and diastolic blood pressures of 93 ± 6 and 65 ± 5 mmHg, respectively. This rapid, minimally invasive protocol is a powerful platform for cardiovascular device development.
David Santer, Paul Ecker, Judith Radloff, Katharina Heissl, Smruti Mirchandani, Sabine Leitner, Bruno Mora, Martin Czerny, Roman Gottardi, Michael Moore, Bruno K. Podesser   +10 more
wiley   +1 more source