Results 191 to 200 of about 84,799 (276)

Precision mRNA Delivery via Ultrasound‐Controlled Release Perfluorocarbon Emulsions: An Innovative Ultrasound Theranostic Strategy with 19F MRI Feasibility

open access: yesSmall, EarlyView.
A key challenge in advancing messenger RNA (mRNA) therapeutics in cardiovascular diseases lies in achieving controlled release at the precise site within the vasculature. This study presents the development of perfluorocarbon nanodroplets with exceptional theranostic potential, enabling real‐time tracking through ultrasound and fluorine‐19 (19F ...
Haikun Liu   +14 more
wiley   +1 more source

What Happens After Menopause (WHAM)? A Progress Report of a Prospective Controlled Study of Women After Pre‐Menopausal Risk‐Reducing Bilateral Salpingo‐Oophorectomy

open access: yesBJOG: An International Journal of Obstetrics &Gynaecology, EarlyView.
ABSTRACT Surgical menopause, the removal of both ovaries prior to natural menopause, may impact short‐and long‐term physical and emotional health. An increasingly common cause of surgical menopause is risk‐reducing salpingo‐oophorectomy (RRSO) in those at high inherited risk of ovarian cancer.
Sarah A. L. Price   +12 more
wiley   +1 more source

Risk of Cancer With Hormone Replacement Therapy: A Narrative Review

open access: yesBJOG: An International Journal of Obstetrics &Gynaecology, EarlyView.
ABSTRACT Hormone replacement therapy (HRT) remains the cornerstone of menopausal symptom management, effectively alleviating vasomotor symptoms and genitourinary syndrome, whilst mitigating long‐term risks such as osteoporosis. However, despite an increasing body of evidence on the relative safety of HRT, earlier studies that demonstrated an increased ...
Gabriella Yongue   +3 more
wiley   +1 more source

Cretaceous lacewing larvae with binocular vision demonstrate the convergent evolution of sophisticated simple eyes

open access: yesInsect Science, EarlyView.
We report three ca. 100 million‐year‐old lacewing larvae with extraordinarily large stemmata. One of them additionally has a very wide head, which represents a previously unknown morphology. The arrangement of the stemmata indicates stereoscopic vision in these predatory larvae.
Carolin Haug   +9 more
wiley   +1 more source

Bridging the Late Antique Gap in Northwest Arabia: New Archaeological Evidence on the Occupation of Wādī al‐Qurā (al‐ʿUlā [AlUla], Saudi Arabia) Between the Third and Seventh Centuries CE

open access: yesArabian Archaeology and Epigraphy, EarlyView.
ABSTRACT In 2019, the Dadan Archaeological Project (CNRS/RCU/AFALULA) identified a Late Antique village 1 km south of ancient Dadan in the al‐ʿUlā valley (northwest Saudi Arabia). Three excavation seasons at this site (2021–2023) have uncovered a massive building constructed in the late third or early fourth cent.
Jérôme Rohmer   +11 more
wiley   +1 more source

Clinical and Patient‐Reported Outcomes of the SuperPath Versus Hardinge Approach in Total Hip Replacement for Osteoarthritis: A Retrospective Cohort Study

open access: yesANZ Journal of Surgery, EarlyView.
ABSTRACT Background There are various surgical approaches for total hip replacement (THR), such as the Direct Lateral (Hardinge), anterior, and supra‐acetabular (SuperPath) approach. The aim of this study was to compare the post‐operative clinical, functional and quality of life outcomes of the SuperPath and Direct Lateral approach in hip ...
Akın Sönmezdağ   +4 more
wiley   +1 more source

The application of artificial intelligence in blind ultrasound sweep diagnostics for prenatal medicine: A systematic literature review

open access: yesActa Obstetricia et Gynecologica Scandinavica, EarlyView.
Artificial intelligence enables the interpretation of blind ultrasound sweeps for prenatal diagnostics. Applications include accurate gestational age estimation, amniotic fluid segmentation, fetal presentation classification, and placental localization.
Johanna Schott   +6 more
wiley   +1 more source

Maternal exercise improves vascular function in hypertensive offspring via A‐kinase anchoring protein 150 gene (Akap5) epigenetic modifications

open access: yesBritish Journal of Pharmacology, EarlyView.
Background and Purpose Regular physical activity is an effective non‐pharmacological approach to hypertension management and maternal exercise improves offspring cardiovascular health, although mechanisms remain unclear. A‐kinase anchoring protein 150 (AKAP150) targets protein kinase Cα to L‐type Ca2+ channels (CaV1.2), enhancing vascular tone in ...
Fang Qiu   +8 more
wiley   +1 more source

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