Results 91 to 100 of about 137,379 (339)

Predictors of the need for supportive femoral approach during transvenous extraction of pacemaker and defibrillator leads in Japanese patients

open access: yesJournal of Arrhythmia, 2020
Background Studies on femoral approach during transvenous lead extraction (TLE) are limited. Methods We retrospectively evaluated 75 patients undergoing TLE from September 2014 through November 2019 via supportive femoral approach (Femoral/Superior group;
Tsuyoshi Isawa   +3 more
doaj   +1 more source

NDRG1‐Driven Lactate Accumulation Promotes Lung Adenocarcinoma Progression Through the Induction of an Immunosuppressive Microenvironment

open access: yesAdvanced Science, EarlyView.
NDRG1 drives lactate accumulation and histone lactylation in lung adenocarcinoma, promoting immunosuppression via M2 macrophage polarization and CD8⁺ T cell inhibition. High NDRG1 expression correlates with poor prognosis, an immunosuppressive microenvironment, and immunotherapy resistance.
Gujie Wu   +14 more
wiley   +1 more source

A Large Vascular Leiomyoma in Femoral Triangle

open access: yesIndian Journal of Vascular and Endovascular Surgery, 2016
Angioleiomyoma is a benign soft-tissue vascular tumor arising from the smooth muscle of the tunica media. It is more common in females. Lower extremities, particularly the lower leg and foot, are more affected. Cutaneous vessels are common site of origin.
Bhavinder Arora
doaj   +1 more source

Coactosin‐Like Protein Reduces Prostaglandin D2 Production in Alveolar Macrophages and Alleviates Allergic Airway Inflammation

open access: yesAdvanced Science, EarlyView.
Coactosin‐like protein inhibits prostaglandin D₂ (PGD2) secretion by modulating alveolar macrophage polarization, thereby suppressing activation of the PGD2 receptor CRTH2 in Th2‐associated immune cells and alleviating allergic airway inflammation.
Li‐Long Pan   +12 more
wiley   +1 more source

AN UNCOMMON BILATERAL VARIANT OF DRAINAGE OF THE SMALL SAPHENOUS VEIN: CASE REPORT

open access: yesArta Medica, 2020
This study reports an unusual variant of drainage of the small saphenous vein identified during routine anatomic dissection of a male cadaver at the Human Anatomy Department.
Anastasia Bendelic, Ilia Catereniuc
doaj  

Endocardial Pacemaker Implantation in Neonates and Infants [PDF]

open access: yes, 2006
Transvenous pacemaker lead implantation is the preferred method of pacing in adult patients. Lead performance and longevity are superior and the implantation approach can be performed under local anaesthetic with a very low morbidity.
Ayabakan, Canan, Rosenthal, Eric
core   +2 more sources

Novel Quaternary Ammonium Salt‐Linked STING Agonist Antibody‐Drug Conjugate: Synergistic Activation of Tumor Immunity with Mitigated Off‐Target Toxicity

open access: yesAdvanced Science, EarlyView.
Novel quaternary ammonium salt‐linked STING agonist ADC demonstrates high potency, stability, enhanced solubility, and reduced off‐target toxicity, potently activating the STING pathway in the tumor microenvironment through the synergistic action of the Fab and Fc regions of antibodies (activity switch‐on) while exhibiting ≈20 fold lower activity in ...
Yu Long   +17 more
wiley   +1 more source

Parvalbumin Interneuron‐Dependent Hippocampal Neurogenesis Evoked by Prolonged Rhythmic Light Flicker

open access: yesAdvanced Science, EarlyView.
This study demonstrates that prolonged rhythmic 40 Hz light flicker enhances spatial learning by stimulating PV interneuron‐dependent neurogenesis. The light flicker selectively activates PV interneurons, which enhances GABAergic support for the integration of immature neurons in the adult dentate gyrus.
Hai Yan   +16 more
wiley   +1 more source

Cardiac resynchronization therapy: Femoral approach

open access: yesRevista Portuguesa de Cardiologia, 2017
We describe the case of a 62-year-old female patient with bilateral subclavian vein occlusion, in whom a cardiac resynchronization system was implanted via a femoral vein.
Luís Brandão   +6 more
doaj  

Bidirectional Interaction Between the Brain and Bone in Traumatic Brain Injury

open access: yesAdvanced Science, EarlyView.
Traumatic brain injury (TBI) disrupts the blood–brain barrier and activates neuroimmune responses, causing metabolic disturbances and long‐term bone mass loss. Concurrent fractures accelerate healing and enhance osteogenesis but disrupt regulatory mechanisms, leading to altered bone dynamics and exacerbating neuroinflammation, complicating recovery ...
Wei Zhang, Jun Zou, Lingli Zhang
wiley   +1 more source

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