Results 191 to 200 of about 505,611 (358)

Photon-Counting Micro-CT for Bone Morphometry in Murine Models. [PDF]

open access: yesTomography
Nadkarni R   +5 more
europepmc   +1 more source

Single Cell and Spatial Transcriptomics Define a Proinflammatory and Profibrotic Niche After Kidney Injury

open access: yesAdvanced Science, EarlyView.
By integrating single‐cell RNA sequencing and spatial transcriptomics, tenascin C (TNC) is unveiled as a central organizer of the proinflammatory and profibrotic niche in kidney fibrosis. TNC promotes macrophage activation through TLR4/NF‐κB signaling, leading to renal inflammation and fibrosis.
Li Li   +14 more
wiley   +1 more source

A Hypoxia‐Responsive Single‐Atom Sonozyme for Targeted Sonocatalytic Therapy in Alleviating Atherosclerotic Plaque

open access: yesAdvanced Science, EarlyView.
A tetranitrogen‐coordinated single‐atom manganese catalyst (SMC) is fabricated with outstanding sonosensitization efficiency and multi‐enzyme‐like catalytic properties. To enable better targeting of M1 macrophages, hyaluronic acid (HA) is applied to modify the surface of SMC, yielding SMC‐HA nanozymes.
Qiaofei Chen   +14 more
wiley   +1 more source

Load and failure behavior of human muscle samples in the context of proximal femur replacement [PDF]

open access: gold, 2016
Stefan Schleifenbaum   +7 more
openalex   +1 more source

Sabotaged Integral HSC Heterogeneity Underlies Essential Thrombocythemia Development

open access: yesAdvanced Science, EarlyView.
Single‐cell RNA sequencing (scRNA‐seq) maps how distinct driver mutations remodel hematopoietic stem cell (HSC) programs across essential thrombocythemia (ET). Comparative analysis uncovers both shared and subtype‐specific molecular signatures, identifies a triple‐negative (TN)‐associated HSC population enriched with malignant traits, and reveals the ...
Jingyuan Tong   +21 more
wiley   +1 more source

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