Results 171 to 180 of about 184,427 (219)

Towards a Compositional Framework for Describing Human Phenotypes

Advanced Science, EarlyView.
The Phenotype Assembly Method (PhenoAM) decomposes phenotype variables into measurable Features and typed Qualifiers, enabling standardized, machine‐readable Phenome Data Elements (PhenoDEs) that preserve measurement context. Applied in the International Human Phenome Project (IHPP), the framework yields 58 371 PhenoDEs and supports component‐level ...
Wanting Hu, Yunchao Ling, Xinyue Hu, Wei Chen, Rong Zhou, Xinhao Zhuang, Yanfeng Jiang, Jialu Zhao, Xingdong Chen, Jingchun Luo, Li Jin, Guoqing Zhang   +11 more
wiley   +1 more source

Polyethylene Exchange During Retrograde Intramedullary Nailing in the Treatment of Periprosthetic Distal Femur Fractures: A Registry Pilot Analysis. [PDF]

J Am Acad Orthop Surg Glob Res Rev
Miceli JG, Doerr NA, Andriani NT, Miles DT, Porter AS, Jankowski JM, Liporace FA, Yoon RS.   +7 more
europepmc   +1 more source

Multi‐Tissue Crosstalk Regulating Meniscus Healing Under Inflammation and Physiological Loading

Advanced Science, EarlyView.
Using a novel Meniscus‐on‐a‐chip (MoC) model integrated with a meniscus‐specific bioreactor, this study investigated the roles of multi‐tissue crosstalk that regulates injury, healing, and degeneration of the meniscus injury under inflammation and pathophysiological loading.
Hun Jin Jeong, Elen Zhu, Min Seo Kang, Ming Wang, Sam Comito, Chang H. Lee   +5 more
wiley   +1 more source

Protocol for selective in vivo labeling of bone marrow plasma cells by intrafemoral antibody injection in mice. [PDF]

STAR Protoc
Tong Z, Zhu Y, Lv H, Liu S, Xu C.
europepmc   +1 more source

Palaeoproteomic Deconvolution of Physical and Genetic Collagen Mixtures

Advanced Science, EarlyView.
ClassiCOL_v2 uses a novel “peptide patching” framework that treats any collagen sample as a patchwork of peptide sequences derived from phylogenetically related species. This allows the algorithm to simultaneously resolve two previously intractable problems: multi‐species samples and/or database deficiencies.
Ian Engels, Tristan Dedrie, Synnøve K. Mo, Simon Van de Vyver, Thijs R. A. Vandenbroucke, Kévin Di Modíca, Jan Decher, Alice Toso, Dieter Deforce, Simon Daled, Alexandra Burnett, Grégory Abrams, Maarten Dhaenens   +12 more
wiley   +1 more source

Multifocal osseous and cutaneous Rosai-Dorfman-Destombes disease presenting as an aggressive intramedullary femoral lesion. [PDF]

Radiol Case Rep
Aldubaiyan KW, AlRehaily HA, AlJarie MA, Alabdulkareem OA, Alzahrani AM, Aldahlawi AA, Alhumaydhi AO, Alsalman MJ.   +7 more
europepmc   +1 more source

Chinese Expert Consensus on the Clinical Application of Finerenone in Geriatric Comorbidities

AGING MEDICINE, EarlyView.
Mineralocorticoid receptor (MR) overactivation drives inflammation, oxidative stress, and fibrosis in the heart, kidneys, and vasculature, leading to cardiorenal dysfunction. MR signaling promotes hypertrophy, remodeling, and injury through pathways like oxidative stress and inflammation, resulting in vascular stiffness and progressive organ damage ...
Xiaoming Wang, Cuntai Zhang
wiley   +1 more source

Proximal Femoral Fractures Following Ipsilateral Transfemoral Amputation in Working-Age Men: A Report of Two Cases. [PDF]

Cureus
Toda M, Oshima T.
europepmc   +1 more source

Radical Resection of the Third Portion of the Duodenum for Secondary Aortoduodenal Fistula

Annals of Gastroenterological Surgery, EarlyView.
Secondary aortoduodenal fistula most commonly involves the third portion of the duodenum and requires definitive management of both vascular and gastrointestinal components. We demonstrate a step‐by‐step technique for radical duodenal resection and reconstruction performed in structured collaboration with cardiovascular surgeons.
Koji Kubota, Akira Shimizu, Tsuyoshi Notake, Tatsuichiro Seto, Yuji Soejima   +4 more
wiley   +1 more source

Management of Infected Non-union of Long Bones Using Antibiotic Cement-Coated Intramedullary Nails: A Prospective Case Series. [PDF]

J Orthop Case Rep
Lingayat MB, Ghazi MS, Dhage OB, Sundriyal P, Shelke KU, Bhujbal D.   +5 more
europepmc   +1 more source