Results 191 to 200 of about 248,024 (308)

Outcomes of Megaprosthetic Reconstruction After Tumor Resection of the Distal Femur and Proximal Tibia: A Single-Center Retrospective Study of 241 Cases. [PDF]

J Clin Med
Ayhan B, Yoğurt SB, Ayhan ZD, Ulucaköy C, Atalay İB.   +4 more
europepmc   +1 more source

Inhibition of KDEL Receptors Remodels the Tumor Microenvironment for T Cell Independent Tumor Regression

Advanced Science, EarlyView.
Inhibition of KDELR2 in a small fraction of tumor cells generates sustainable immunogenic cell death conditions within the tumor microenvironment. These conditions promote the regression of tumors in a T cell independent manner. During regression, macrophages prime T cells that subsequently provide systemic protection against recurrence. The potency of
Shakti P Pattanayak, Hong Wang, Belinda Willard, Timothy A. Chan, William C Merrick, Zheng‐Rong Lu, Boaz Tirosh   +6 more
wiley   +1 more source

Aneurysmal Bone Cyst Presenting as a Pathological Subtrochanteric Femur Fracture in an Adolescent: A Case Report. [PDF]

J Orthop Case Rep
Rai CR, Gavhale SV, Chandele V, Yadav AP, Torne CS, Karpe VB.   +5 more
europepmc   +1 more source

Targeting a Myeloid–Regulatory B Cell Network Reverses Immune Paralysis in Periprosthetic Joint Infections

Advanced Science, EarlyView.
Periprosthetic joint infection establishes a sophisticated immunosuppressive network between CXCR4+ PMN‐MDSCs and Bregs, inducing profound CD8+ T cell paralysis. Alendronate effectively disrupts this CXCR4+ PMN‐MDSC–Breg axis by targeting STAT3, thereby restoring local immune surveillance.
Jintao Wu, Shutao Zhang, Yumin Lin, Juyang Jiao, Zhiwei Fu, Qimin Hong, Ziyi Zhao, Xinhua Qu, Fei Su, Bing Yue   +9 more
wiley   +1 more source

Ultra‐Radiostable Covalent Conformationally Interlocked Networks Enabling a Universal Radiometal‐Labeling Platform for Cancer Radioembolization

Advanced Science, EarlyView.
Conjugated poly(imide dioxime)‐based microspheres establish a radiometal coordination‐driven conformational interlocked network with ultra‐high radiostability. This platform enables low‐temperature, multi‐radionuclide labeling for SPECT/PET/MRI imaging and radionuclide therapy. Mechanistic insights from EXAFS and DFT reveal enhanced stability, while in
Xiao Xu, Zhenwen Zhao, Yangjie Wang, Zhigang Liu, Zhijie Liu, Xiaoling Li, Zhichen Mao, Lu Xu, Gan Lin, Gang Liu, Hongjuan Ma   +10 more
wiley   +1 more source

Contrasting life history in the diminutive Dimetrodon species from North America and Germany. [PDF]

Sci Rep
Canoville A, Knaus PL, Marchetti L, Fröbisch J.   +3 more
europepmc   +1 more source

“Intrapericardial Approach” for Venous Outflow Reconstruction in Living‐Donor Liver Transplantation for Budd‐Chiari Syndrome: Surgical Techniques and LongTerm Outcomes

Annals of Gastroenterological Surgery, EarlyView.
Unlike deceased‐donor liver transplantation, living‐donor liver transplantation (LDLT) for Budd‐Chiari Syndrome (BCS) presents distinctive challenges in hepatic venous (HV)‐outflow reconstruction because diseased HV–inferior vena cava (IVC) cannot be entirely replaced with healthy donor vessels.
Koichiro Hata, Tetsuya Tajima, Satoshi Ogiso, Shinji Uemoto, Etsuro Hatano   +4 more
wiley   +1 more source

Pseudoaneurysm of the Medial Femoral Circumflex Artery following Surgical Fixation of Trochanteric Femur Fracture: A Case Report. [PDF]

J Orthop Case Rep
Singh AK, Jha S, Agarwal P.
europepmc   +1 more source

Age and Regional Trends in Groin Hernia Surgery in Japan: An Analysis of Laparoscopic Repair, Outpatient Surgery, and Manual Reduction Using National Database Open Data

Annals of Gastroenterological Surgery, EarlyView.
Using National Database open data from 2014 to 2023, this nationwide study visualizes age‐, sex‐, and region‐specific trends in groin hernia surgery in Japan. Laparoscopic surgery, outpatient surgery, and manual reduction were analyzed to estimate lifetime surgical burden and patterns of emergency‐related healthcare utilization at the population level.
Masanori Sato, Kyosuke Miyazaki, Tatsuya Tazaki, Itsuro Nagae, Taketo Matsubara, Saseem Poudel, Tsuyoshi Takagi, Hidetoshi Wada   +7 more
wiley   +1 more source

3D-Printed prosthesis for recurrent femoral metastasis with periprosthetic infection: A case report. [PDF]

Exp Ther Med
Li J, Zhang Y, Kang J, Tian C, Chen S, Ning Y, Li H, Xiao Y.   +7 more
europepmc   +1 more source