Results 61 to 70 of about 51,881 (265)

Traumatic bilateral neck of femur fracture in paediatric age: A case report and review of literature [PDF]

, 2022
Indrajeet Kumar, Wasim Ahmed, Reetesh Roshan, Santosh Kumar, Janki Sharan Bhadani   +4 more
openalex   +1 more source

Distinct Immunomodulatory Strategies Guide Mesenchymal Stromal/Stem Cell‐Mediated Bone Regeneration

Advanced Science, EarlyView.
Bone regeneration by mesenchymal stem cells is strongly influenced by immune signals. This study shows that priming stem cells with regulatory immune cells or an inflammation‐resolving lipid molecule enhances bone formation through distinct immune pathways.
Salwa Suliman, Carla Alvarez Rivas, Aashish Srivastava, Nora Marek, Kamal Mustafa, Alpdogan Kantarci   +5 more
wiley   +1 more source

FEMORAL NECK ANTEVERSION: IS THE SIDE WISE DIFFERENCE SIGNIFICANT?

Gomal Journal of Medical Sciences, 2014
Background: Femoral anteversion is one of the most important parameter of femur anatomy and geometry having important clinical implications. The objective of this study was to determine the side wise variation in femoral neck anteversion angle in adult
Wali Ullah Khan, Malik Javaid Iqbal, Muhammad Marwat, Maqbool Ilahi   +3 more
doaj  

Context‐Dependent Role of GDF15: GDF15+ Tumor‐Associated Macrophages Suppress OSCC Progression by Enhancing Phagocytosis

Advanced Science, EarlyView.
This study identifies GDF15+ TAMs as a cell subset mediating tumor regression after immunotherapy. Macrophage‐intrinsic GDF15 enhances phagocytosis and antigen cross‐presentation to CD8+ T cells through the NF‐κB signaling pathway, thereby inhibiting tumor progression.
Xinyu Zhou, Zhihang Zhou, Houyu Ju, Chaoyang Guo, Fangxing Zhu, Yiyi Zhang, Xu Chen, Tongchao Zhao, Laiping Zhong, Jingzhou Hu   +9 more
wiley   +1 more source

Identification of a Force‐Induced Sox9+Acan+ Transitional Subpopulation Linked to FGF2–FGFR2–ERK Signaling in Orthodontic Bone Remodeling

Advanced Science, EarlyView.
Mechanical loading induces a previously unrecognized Sox9+Acan+ transitional mesenchymal cell population in the periodontal ligament that promotes osteoclastogenesis via the FGF2–FGFR2–ERK axis. Targeting this mechanoresponsive stromal population using a localized GelMA@siRNA delivery strategy attenuates pathological osteoclast overactivation and root ...
Miao Tan, Minyu He, Mingrui Zong, Qiya Tang, Yinan Liu, Jiaju Deng, Shun Huang, Xiaoxiao Lei, Jie Li, Lan Huang   +9 more
wiley   +1 more source

QCT-based spatio-temporal aging atlas of the proximal femur BMD and cortical geometry

Bone Reports
Aging is associated with an increased risk of fragility fractures at the hip, resulting from a loss of bone mass. While this loss is typically reported as a decreased mean areal bone mineral density (aBMD) in the proximal femur or the femoral neck, its ...
Alice Dudle, Yvan Gugler, Osman Berk Satir, Jan Gewiess, Stefan Klein, Philippe Zysset   +5 more
doaj   +1 more source

BONE DENSITY OF THE LUMBAR SPINE L1-L4 AND FEMUR NECK ON CHILDBEARING AGE WOMAN WHO ARE IMPLANT AND NON HORMONAL CONTRACEPTIVES ACCEPTORS.

Journal of Midwifery, 2018
mplant contraception is one type of contraceptive in the form of an implant made of silastik rubber containing the progestin hormone (levonogestrel) attached to the upper arm.
Kuswati Kuswati, Rohmi Handayani
doaj   +1 more source

Neuronal Cholesterol Deficiency Mediated by Astrocytic SREBP2 Downregulation Leads to Postoperative Cognitive Dysfunction Through Impairment of Hippocampal Synaptic Plasticity and Excitatory Synaptic Transmission

Advanced Science, EarlyView.
The results showed that the reduction of plasma 24‐hydroxycholesterol (24‐OHC) was related to the cognitive decline in elderly surgical patients. Neuroinflammation induced by anesthesia and surgery significantly downregulated SREBP2 in hippocampal reactive astrocytes, resulting in reduced cholesterol synthesis.
He Huang, Chenrui Zhou, Chen Chen, Huimei Tang, Wei Dong, Jie Wan, Weiye Kang, Ao Sun, Yiqi Liu, Chunhui Jin, Xiaobin Lyu, Yankun Zhu, Chenghua Zhou, Yuqing Wu   +13 more
wiley   +1 more source

Multimodal AI‐Driven Identification of Dehydrocostus Lactone as a Potent Renal Fibrosis Attenuator Targeting IQGAP1

Advanced Science, EarlyView.
Renal fibrosis, a hallmark of CKD, lacks effective treatments. Herein, we developed a multimodal AI model (TCM‐SPred) to identify anti‐fibrotic agents and found that dehydrocostus lactone (DCL) targets IQGAP1 to inhibit Wnt signaling, blocking the interaction between IQGAP1 and CCT3, demonstrating potent anti‐fibrotic activity in vitro and in vivo ...
Weijiang Lin, Wenzhuo Xu, Kang Liu, Ping Wang, Zhenzhen Zhu, Wenyu Lu, Zhe Zheng, Xiaoqian Peng, Xunkai Yin, Shulan Mei, An Pan, Jian Liu, Lihong Hu   +12 more
wiley   +1 more source

The Effect of Cement Placement on Augmentation of the Osteoporotic Proximal Femur

Geriatric Orthopaedic Surgery & Rehabilitation, 2010
Femoroplasty, the augmentation of the proximal femur, has been shown in biomechanical studies to increase the energy required to produce a fracture and therefore may reduce the risk of such injuries.
Edward G. Sutter MS, Simon J. Wall FRCS, Simon C. Mears MD, PhD, Stephen M. Belkoff PhD   +3 more
doaj   +1 more source