ABSTRACT Introduction Periureteral IgG4‐related disease (IgG4‐RD) is rare and can mimic upper tract urothelial carcinoma (UTUC), sometimes leading to unnecessary nephroureterectomy. Diagnosis is challenging when endoscopic biopsy is inconclusive and percutaneous biopsy is unsafe.
Takeshi Yoshida +9 more
wiley +1 more source
Slit2/Robo Signaling Restores Diabetic Erectile Function via Neurovascular Remodeling
ABSTRACT Background Diabetes mellitus‐induced erectile dysfunction (DMED) is a common and debilitating vascular‐neurogenic complication of diabetes. The poor responsiveness of DMED patients to phosphodiesterase type‐5 inhibitors underscores the need for therapies capable of restoring both endothelial integrity and cavernous nerve function.
Sen Fu +7 more
wiley +1 more source
Autophagy in MASLD: A Metabolic and Precision Medicine Perspective
ABSTRACT Metabolic dysfunction‐associated steatotic liver disease (MASLD) is the most common chronic liver condition worldwide and a major contributor to cirrhosis and hepatocellular carcinoma (HCC). While metabolic triggers such as obesity and insulin resistance are key drivers of MASLD, growing evidence has identified defects in intracellular quality
Alessandra Cazzaniga +4 more
wiley +1 more source
Middle cerebral artery fenestration presenting with cerebral ischemia: a case report and review of the literature. [PDF]
Bi Y, Li Z, Sun W, Zou L, Li H, Mei B.
europepmc +1 more source
A Quarter Century of EHD Protein Research: From Endosomal Recycling to Ciliopathies
Human EHD protein subcellular localization. ABSTRACT Eps15 homology domain‐containing proteins comprise a conserved family of membrane‐remodeling ATPases that regulate endocytic trafficking, membrane fission, receptor recycling, primary ciliogenesis and membrane dynamics across eukaryotes. Since the initial identification of EHD1 and its Caenorhabditis
Devin Frisby +3 more
wiley +1 more source
Liver sinusoidal endothelial cell fenestrations in metabolic liver disease: from molecular mechanisms to therapeutic perspectives. [PDF]
Al-Mughalles AS +10 more
europepmc +1 more source
Treatment of discospondylitis in dogs: A systematic review
Abstract Background Both medical and surgical techniques have been reported to manage canine discospondylitis, although data on clinical effectiveness and long‐term prognosis remain limited. Methods A systematic review of studies on treatment approaches, follow‐up data and investigation methods was conducted.
Vasileios Ioannis Vallios +4 more
wiley +1 more source
Diagnostic challenges in internal carotid artery fenestration: a 78-year-old woman presenting with transient ischemic attack-a case report. [PDF]
Aalinezhad M +4 more
europepmc +1 more source
FGL2‐HDAC11 Drives Immunothrombosis via NETs‐Mediated Endothelial Capillarization in MASLD Fibrosis
ABSTRACT Metabolic dysfunction–associated steatotic liver disease (MASLD) is frequently accompanied by hepatic fibrosis and systemic cardiovascular complications; however, the mechanistic interplay between coagulation abnormalities and disease progression remains poorly defined.
Xitang Li +16 more
wiley +1 more source
ARumenamides as Multitarget Ion Channel Modulators: Insights from Fenestration-Focused Docking, ADMET Profiling, and Molecular Dynamics. [PDF]
Abdelsayed M, Boulaamane Y.
europepmc +1 more source

