Results 91 to 100 of about 24,272 (272)

VEGF-mediated tight junctions pathological fenestration enhances doxorubicin-loaded glycolipid-like nanoparticles traversing BBB for glioblastoma-targeting therapy

Drug Delivery, 2017
The existence of blood–brain barrier (BBB) greatly hindered the penetration and accumulation of chemotherapeutics into glioblastoma (GBM), accompany with poor therapeutic effects.
Lijuan Wen, Yanan Tan, Suhuan Dai, Yun Zhu, Tingting Meng, Xiqin Yang, Yupeng Liu, Xuan Liu, Hong Yuan, Fuqiang Hu   +9 more
doaj   +1 more source

Carbon dots as a smart nanoplatform for the blood‐brain barrier penetration and ischemic stroke therapy

Responsive Materials, EarlyView.
This review presents the structure and transport routes of the blood‐brain barrier, summarizes the ischemic stroke pathophysiological cascade, and discusses the BBB‐crossing mechanisms and multitarget therapeutic effects of carbon dots, demonstrating their promising theranostic potential for ischemic stroke.
Yanhan Huang, Xuan Hou, Haiping Zhao, Qi Kong, Xiayan Wang, Xiaokun Geng, Zaicheng Sun   +6 more
wiley   +1 more source

Persistent fenestration may be a marker for physiologic intolerance after Fontan completion [PDF]

, 2014
BackgroundWe sought to evaluate the medium-term implications of fenestration status.MethodsBetween 1994 and 2012, 326 patients received an extracardiac Fontan (hospital mortality n = 6, 1.8%).
Zhu, Jiaquan, Chetan, Devin, Coles, John G., Christopher A. Caldarone, Caldarone, Christopher A., Jiaquan Zhu, Yasuhiro Kotani, Arezou Saedi, Osami Honjo, Van Arsdell, Glen S., John G. Coles, Grosse-Wortmann, Lars, Glen S. Van Arsdell, Honjo, Osami, Devin Chetan, Lars Grosse-Wortmann, Kotani, Yasuhiro, Saedi, Arezou   +17 more
core   +1 more source

Gut microbiota dysbiosis in the inflammatory pathogenesis of diabetic retinopathy

VIEW, EarlyView.
This graphical abstract illustrates how gut dysbiosis drives diabetic retinopathy through the gut‐retina axis, a process unfolding in three interconnected stages. First, in the gut, a decrease in beneficial bacteria and an increase in pro‐inflammatory taxa compromise the intestinal barrier, causing a “leaky gut” that allows LPS to translocate into the ...
Junyan Hu, Jingxiang Zhong
wiley   +1 more source

Clinical Outcome of Fenestration as Minimally Invasive Surgery for Lumbar Disc Herniation: Successes and Obstacles

Journal of the Dow University of Health Sciences, 2022
Objective: To assess the clinical outcome of fenestration as minimally invasive surgery among patients with  lumbar disc herniation undergoing microdiscectomy.
Aurangzeb Kalhoro, Abdul Samad Panezai, Sher Hassan, Farrukh Javeed, Lal Rehman   +4 more
doaj  

Decreased Production of Tissue Plasminogen Activator in Endothelial Cells From Nasal Polyps

World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Introduction Previous studies have demonstrated that chronic rhinosinusitis with nasal polyps (CRSwNP) is characterized by excessive fibrin deposition which is related to impaired production of tissue plasminogen activator(t‐PA) by epithelial cells.
Qian‐Qian Zhang, Chen Zhang, Jia‐Ni Chen, Fu‐Ying Cheng, Yi‐Zhang Wang, Shi‐Rui Xue, Huan Wang, De‐Hui Wang, Xi‐Cai Sun, Li Hu   +9 more
wiley   +1 more source

To fenestrate or not to fenestrate [PDF]

The Journal of Thoracic and Cardiovascular Surgery, 2011
Schreiber, Christian, Hörer, Jürgen, Lange, Rüdiger   +2 more
openaire   +1 more source

Clinical use of reserved guide wire fenestration and Viabahn-covered stent in Stanford type B aortic dissection with left subclavian artery involvement

Journal of International Medical Research
This study aimed to evaluate the efficacy of external fenestration using a reserved guide wire and a Viabahn-covered stent in Stanford type B aortic dissection that involves the left subclavian artery.
Haoxiang Zhu, Huipeng Zhu
doaj   +1 more source

A New Model of Feeding Biomechanics Based on Tied‐Arch Principles

Integrative Zoology, EarlyView.
This new biomechanical model explains the major stress and strain patterns generated through the cranium during biting. The model proposes that the cranium resolves bite‐induced reaction forces through arcs of compressive stress that span the cranial structure between biting teeth and both jaw joints.
D. Rex Mitchell
wiley   +1 more source

Lamina terminalis fenestration

, 2014
Chohan et al.3 (Chohan MO, Carlson AP, Hart BL, et al: Lack of functional patency of the lamina terminalis after fenestration following clipping of anterior circulation aneurysms. Clinical article. J Neurosurg 119:629–633, September 2013).
Tomasello Francesco, Cardali Salvatore, Conti Alfredo, Angileri Filippo   +3 more
core   +1 more source