Results 111 to 120 of about 10,177 (218)
Glucocorticoids modulate drug transporter function in human fetal brain endothelial cells
The Journal of Physiology, EarlyView.Abstract figure legend P‐glycoprotein and breast cancer resistance protein are the most prominent drug transporters at the fetal blood–brain barrier. We isolated primary human fetal brain endothelial cells from early and mid‐gestation cerebral microvessels and exposed them to glucocorticoids cortisol and dexamethasone in vitro.
Nikola Ivanovski +3 more
wiley +1 more source
Slit2/Robo Signaling Restores Diabetic Erectile Function via Neurovascular Remodeling
Andrology, Volume 14, Issue 6, Page 1831-1846, September 2026.ABSTRACT Background Diabetes mellitus‐induced erectile dysfunction (DMED) is a common and debilitating vascular‐neurogenic complication of diabetes. The poor responsiveness of DMED patients to phosphodiesterase type‐5 inhibitors underscores the need for therapies capable of restoring both endothelial integrity and cavernous nerve function.
Sen Fu +7 more
wiley +1 more source
Autophagy in MASLD: A Metabolic and Precision Medicine Perspective
Liver International, Volume 46, Issue 9, September 2026.ABSTRACT Metabolic dysfunction‐associated steatotic liver disease (MASLD) is the most common chronic liver condition worldwide and a major contributor to cirrhosis and hepatocellular carcinoma (HCC). While metabolic triggers such as obesity and insulin resistance are key drivers of MASLD, growing evidence has identified defects in intracellular quality
Alessandra Cazzaniga +4 more
wiley +1 more source
A Quarter Century of EHD Protein Research: From Endosomal Recycling to Ciliopathies
Traffic, Volume 27, Issue 3, September 2026.Human EHD protein subcellular localization. ABSTRACT Eps15 homology domain‐containing proteins comprise a conserved family of membrane‐remodeling ATPases that regulate endocytic trafficking, membrane fission, receptor recycling, primary ciliogenesis and membrane dynamics across eukaryotes. Since the initial identification of EHD1 and its Caenorhabditis
Devin Frisby +3 more
wiley +1 more source
FGL2‐HDAC11 Drives Immunothrombosis via NETs‐Mediated Endothelial Capillarization in MASLD Fibrosis
Advanced Science, Volume 13, Issue 44, 7 August 2026.ABSTRACT Metabolic dysfunction–associated steatotic liver disease (MASLD) is frequently accompanied by hepatic fibrosis and systemic cardiovascular complications; however, the mechanistic interplay between coagulation abnormalities and disease progression remains poorly defined.
Xitang Li +16 more
wiley +1 more source
Clinical Case Reports, Volume 14, Issue 8, August 2026.ABSTRACT Idiopathic intracranial hypertension (IIH) is a rare but significant complication in patients with systemic lupus erythematosus (SLE). Its diagnosis and management can be challenging, particularly in cases of recurrence. We report the case of a 26‐year‐old Persian female with a history of SLE and hypertension who presented with persistent ...
Leila Poorsaadat +3 more
wiley +1 more source
In Vivo Response to Electrocompacted Tendon‐Derived Thread Scaffolds During Tendon Repair
Journal of Biomedical Materials Research Part B: Applied Biomaterials, Volume 114, Issue 8, August 2026.ABSTRACT Tendon injuries remain a major clinical challenge due to the tissue's limited regenerative capacity and poor remodeling of current allograft‐based therapies. To address these limitations, we developed a tendon‐derived thread (TDT) scaffold by electrocompacting decellularized tendon powder into aligned threads, which were subsequently woven ...
Joohee Choi +5 more
wiley +1 more source
Laryngoscope Investigative Otolaryngology, Volume 11, Issue 4, August 2026.ABSTRACT Objectives To reduce operator‐dependent variability and improve surgical precision, robot‐assisted piston prosthesis placement and crimping during otosclerosis surgery may represent a promising approach. However, dedicated microsurgical forceps for this application are not yet available in clinical practice.
Hannah Daoudi +6 more
wiley +1 more source
Simulating the Luminous and Thermal Performance of Fenestration Systems
Lighting Design + Application, 1987 Papamichael, K.M., Selkowitz, S.E.
openaire +2 more sources
Successful conservative management of suspected primary septic peritonitis in a cat
Veterinary Record Case Reports, Volume 14, Issue 3, August 2026.Abstract A 4‐year‐old, male, neutered, domestic shorthair cat was presented for investigations into lethargy and abdominal effusion. Peritoneal fluid analysis revealed septic neutrophilic inflammation. Extensive investigations or exploratory laparotomy were not possible due to financial constraints.
Alison Robertson +2 more
wiley +1 more source