Results 121 to 130 of about 10,177 (218)

Ammonia Metabolism in the Aging Liver: Emerging Mechanistic Insights

Aging Cell, Volume 25, Issue 8, August 2026.
Liver aging may weaken ammonia‐detoxification reserve by disrupting mitochondrial ureagenesis, GS‐mediated scavenging, glutamine metabolism, and metabolic zonation. This emerging framework links impaired nitrogen handling to potential hepatic stress amplification and systemic crosstalk, while highlighting the need for direct validation in physiological
Heng Zhang, Guangyu Liang, Anding Liu
wiley   +1 more source

A single centre multidisciplinary team retrospective review of fifty cases of robot‐assisted surgery for diaphragmatic and thoracic endometriosis

Acta Obstetricia et Gynecologica Scandinavica, Volume 105, Issue 8, Page 1614-1622, August 2026.
Robot‐assisted multidisciplinary surgery enables safe, efficient, and comprehensive treatment of diaphragmatic and thoracic endometriosis. Evaluation of DTE in specialized centers, in a multidisciplinary fashion, allows for patient‐centered operative planning and could avoid missed disease or incomplete management.
Peter Barton‐Smith, Michal Kawka, Tom Routledge, Rupali Arora, Long R. Jiao   +4 more
wiley   +1 more source

ARumenamides as Multitarget Ion Channel Modulators: Insights from Fenestration-Focused Docking, ADMET Profiling, and Molecular Dynamics. [PDF]

Int J Mol Sci
Abdelsayed M, Boulaamane Y.
europepmc   +1 more source

Flecainide binding dynamics in voltage‐gated sodium channels: A comparative isoform analysis of the state‐dependent block

British Journal of Pharmacology, Volume 183, Issue 15, Page 4145-4162, August 2026.
Background and Purpose Local anaesthetics and class I anti‐arrhythmic drugs block voltage‐gated Na+ channels, but the molecular basis for the isoform differences in drug sensitivity remains unclear. Understanding these mechanisms is essential for optimizing therapeutic efficacy and safety.
Tatsuo Munakata, Etsuko Kumada, Nao Katayama, Hiroki Nakagawa, Akihiko Sunami   +4 more
wiley   +1 more source

Liver sinusoidal endothelial cell fenestrations in metabolic liver disease: from molecular mechanisms to therapeutic perspectives. [PDF]

Cell Commun Signal
Al-Mughalles AS, Ma J, Ma H, Zhang C, Xiao H, Ma X, Zhang Q, Jia C, Han H, Ding BS, Zhang S.   +10 more
europepmc   +1 more source

The Reality of Active Targeting in Nanomedicine: Promise Versus Performance

ChemBioChem, Volume 27, Issue 14, 29 July 2026.
Schematic representation of a multi‐functional nanocarrier decorated with diverse ligands. Ligand type, density and spatial organisation collectively determine targeting behaviour, highlighting the complexity of active targeting beyond simple ligand–receptor interactions.
Francesco Cellesi
wiley   +1 more source

A Fast GPU Algorithm for Complex Fenestration Systems Optimization

Building Simulation Conference proceedings, 2020
Ignacio Decia, Eduardo Fernández, Pablo Ezzatti   +2 more
openaire   +1 more source

Persistent Sciatic Artery and Vein with Iliac Vein Fenestration Presenting as Chronic Venous Insufficiency: A Case Report. [PDF]

Vasc Specialist Int
Sharma G, Yadav RR, Sajjan G.
europepmc   +1 more source

Direct assessment of total cavopulmonary connection power loss with interventional cardiac magnetic resonance in Fontan circulation. [PDF]

J Cardiovasc Magn Reson
Dahshi H, Hussain T, Veeram Reddy S, Arar Y, Gusseva M.   +4 more
europepmc   +1 more source

Intraoperative motor evoked potentials (MEP) improvement predicts functional outcomes in intracranial surgery. [PDF]

Clin Neurophysiol Pract
Velur P, Gong M, Zada G, Briggs R, Velur V.   +4 more
europepmc   +1 more source