Results 41 to 50 of about 10,405 (214)
Contributions of asthma, rhinitis and IgE to exhaled nitric oxide in adolescents
Exhaled nitric oxide fraction (FeNO) is an indicator of allergic airway inflammation. However, it is unknown how asthma, allergic rhinitis (AR) and allergic sensitisation relate to FeNO, particularly among adolescents and in overlapping conditions.
Bess M. Flashner +8 more
doaj +1 more source
We aimed to characterise Alternaria sensitisation trajectories from childhood to adulthood; we compared SPT, whole‐extract sIgE and rAlt a 1, and assessed their longitudinal association with asthma and rhinitis in the Isle of Wight birth cohort. Alternaria sensitisation in the Isle of Wight Birth Cohort emerges mainly in late adolescence and, when ...
Mohammad Leily +7 more
wiley +1 more source
Serotonin Degradation and Lipid Metabolism Regulate Human Tc2 Cell Effector Functions
Human Tc2 cells exhibit a metabolically active phenotype characterized by enhanced glycolysis, mitochondrial respiration, and fatty acid uptake dependent on PPARγ. Alarmins strongly amplify IL‐5 and IL‐13 production in Tc2 cells, supporting a shared immunometabolic program across type 2 lymphocytes.
Sabrina de Souza Ferreira +13 more
wiley +1 more source
Noor Al Khathlan,1 Ayad Mohammed Salem2 1Respiratory Care Department, College of Applied Medical Sciences, Imam Abdulrahman Bin Faisal University, Dammam, Saudi Arabia; 2Department of Physiology, College of Medicine, Imam Abdulrahman Bin Faisal ...
Al Khathlan N, Salem AM
doaj
Foram utilizados sete ovinos alimentados com feno de S. guianensis para avaliar a degradabilidade ruminal dos aminoácidos, o balanço nitrogenado e as concentrações de ácidos graxos voláteis (AGVs) no rúmen. A técnica de sacos de náilon foi empregada para
Márcio Machado Ladeira +5 more
doaj +1 more source
Mitochondrial fatty acid enzyme, CPT1A, is deficient in the airway epithelium of severe asthma patients. Restoration of CPT1A expression improved epithelial barrier integrity via increasing mitochondrial respiration and ATP production in airway epithelial cells. Restoration of deficient epithelial CPT1A may represent a new treatment approach for severe
Muyun Wang +12 more
wiley +1 more source
The impact of fraction of exhaled nitric oxide measurements in patients with asthma exacerbation
BACKGROUND Fraction of exhaled nitric oxide measurements (FENO) is accessible, a fast, non- invasive, highly repeatable test for determining eosinophilic airway inflammation.PURPOSEThe objective of this prospective study is to determine the structure of ...
Majda Drnovšek Kaljanac
doaj
Oxidative Stress and Pteridines in Pediatric Asthma: Relationship to Exhaled Nitric Oxide
Fractional exhaled nitric oxide (FeNO) is a useful marker of airway inflammation in asthmatics. Nitric oxide synthase (NOS) requires tetrahydrobiopterin as a cofactor and produces superoxide during NO generation.
Takeda Taisuke +5 more
doaj +1 more source
O objetivo deste trabalho foi avaliar o hábito alimentar, consumo de matéria seca e desempenho em cabras alimentadas com fenos de rami (Boehemeria nivea G.), soja (Neonotonia wightii (L.) M.) e capim-elefante napier (Pennisetum purpureum Sch ...
José Humberto Vilar da Silva +2 more
doaj +1 more source
This is the first randomised placebo‐controlled trial of intralymphatic immunotherapy using a microcrystalline tyrosine‐adjuvanted grass pollen allergoid. Three ultrasound‐guided ILIT injections were well tolerated and reduced combined symptom‐medication scores compared with placebo. The findings support further optimisation and clinical development of
Lara Šošić +13 more
wiley +1 more source

