Results 51 to 60 of about 10,405 (214)
Nasal epithelial transcriptomics identified three cytokine‐associated epithelial immune programs linked to childhood asthma phenotypes. Age‐associated epithelial polarization shifted from IFN/type‐17‐associated toward type‐2‐associated programs after 3 years of age.
Constanze A. Jakwerth +71 more
wiley +1 more source
ABSTRACT Allergen immunotherapy (AIT) has been acknowledged as the only disease‐modifying treatment for respiratory diseases since its introduction in 1911. Although the efficacy and safety have convincingly been established in numerous randomized clinical trials (RCTs), the AIT study results may vary substantially.
Roy Gerth van Wijk +10 more
wiley +1 more source
Mepolizumab Modifies Blood Eosinophil Proteome and Transcriptome in Severe Eosinophilic Asthma
This study investigates the effect of mepolizumab on the proteomic and transcriptomic profile of blood eosinophils in SEA patients. Mepolizumab reduces the migratory capacity and effector‐related molecular signatures of circulating eosinophils in SEA patients.
Pablo Miguéns‐Suárez +14 more
wiley +1 more source
The utility of measuring FENO in monitoring asthmatic children
Purposes and objectives. Bronchial asthma is the most frequent chronic disease in children and in almost 50% of these cases, it occurs eosinophilic airway inflammation. The most important objective in monitoring asthma is preventing exacerbations by means of good communication between physician, patient and family, a good compliance of the latter and ...
Cristina Popescu, Mihai Craiu
openaire +2 more sources
Asthma Remission From Childhood to Young Adulthood–A Population‐Based Cohort Study
Among 257 participants with asthma at age 8 years, 39% achieved symptom‐based remission by age 24, 29% achieved clinical remission, and 18% achieved complete remission. Male sex increased the likelihood of symptom‐based remission, while food sensitization and overweight/obesity decreased the likelihood.
Lina Broström +6 more
wiley +1 more source
AVALIAÇÃO DE CULTIVARES DE SOJA NA PRODUÇÃO E QUALIDADE DO FENO
Cultivares de soja (Glycine max (L.) Merril), mais utilizados no Rio Grande do Sul para produção de grãos, foram testadas visando a produção e qualidade do feno.
Marcos Weber do Canto +2 more
doaj +1 more source
This study reports exploratory and predominantly post hoc subgroup analyses, according to baseline eosinophil count and FeNO levels. In adults with moderate‐to‐severe uncontrolled asthma, rademikibart produced rapid and sustained improvements in lung function and asthma control.
Michael E. Wechsler +3 more
wiley +1 more source
FeNO and Asthma Treatment in Children
Traditional asthma treatments are typically adjusted in children with asthma using symptoms and spirometry. Treatments tailored in accordance to inflammatory markers, such as fraction of exhaled nitric oxide (FeNO) or sputum eosinophils, are increasing in use.
Lu, Min +4 more
openaire +2 more sources
Background: Fractional exhaled nitric oxide (FeNO) and forced oscillometric technique (FOT) represent noninvasive and sensitive tools for measuring airway inflammation and resistance, respectively, but the studies that use FeNO and FOT to assess patients
Amjed H. Abbas +3 more
doaj +1 more source

