Results 41 to 50 of about 11,409 (147)
Safety and pharmacokinetics of inhaled aloxistatin: A first‐in‐human phase 1 dose escalation trial
British Journal of Clinical Pharmacology, EarlyView.Aims Aloxistatin (E64d) is a membrane‐permeable cysteine protease inhibitor prodrug that is converted by esterases to the active metabolite E64c (loxistatin). This first‐in‐human study evaluated the safety, tolerability and pharmacokinetics of single ascending doses of inhaled E64d in healthy volunteers.
Sebastian Fähndrich +24 more
wiley +1 more source
Crop yield and nutrient balance influenced by shoot biomass management and pig slurry application
Revista Brasileira de Engenharia Agrícola e Ambiental, 2016 Crop systems that export large amounts of nutrients from the farm may require higher doses of animal manure than those needed for grain production. This study aimed to evaluate the yield of crops and to determine the simplified nutrient balance in three ...
Carla M. Pandolfo, Milton da Veiga
doaj +1 more source
iMeta, EarlyView.The Human Biomarker Navigator integrates the disease continuum, biomarker dynamics, cross‐organ biomarker networks, biomarker classification, and technology‐driven paradigms. It maps how biomarkers link multi‐system physiology and pathology across the nervous, respiratory, endocrine, circulatory, immune, digestive, urinary, reproductive, and ...
Meng‐Yao Li +29 more
wiley +1 more source
Correlation between the FeNO Angle and d−p Mixing in {FeNO}7 Complexes
, 2016 The great majority of low-spin {FeNO}7 complexes exhibit FeNO angles of around 140−145°, whereas a small handful are characterized by linear FeNO units. Conspicuously absent are intermediate FeNO angles of 150−170°.
Jeanet Conradie (734755) +1 more
core +1 more source
Phytotherapy Research, EarlyView.ABSTRACT Asthma affects 260–300 million people worldwide. About 20%–35% of patients use medicinal plants with their asthma medication, often without telling their clinicians. Disclosure rates are low; up to 42% of asthma outpatients use herbal products, with no records in their charts.
Emine Kocyigit +5 more
wiley +1 more source
UTILITATEA MĂSURĂRII FENO ÎN MONITORIZAREA COPIILOR CU ASTM BRONŞIC [PDF]
Romanian Journal of Pediatrics, 2014 Scopuri şi obiective. Astmul bronşic este cea mai frecventă boală cronică la copii. În peste 50% din cazurile pediatrice, infl amaţia căilor aeriene este eozinofi lică.
Cristina Popescu, Mihai Craiu
doaj +1 more source
Asthma: From Phenotypes to Endotypes—Beyond Type 2 Inflammation
Respirology, EarlyView.ABSTRACT Asthma is a heterogeneous syndrome featuring variable pathophysiology, clinical presentation and treatment response. This review examines a comprehensive endotype‐phenotype framework for asthma assessment with an emphasis on characteristics beyond T2 inflammatory status alone.
Mario Fernando, Gregory G. King
wiley +1 more source
Complete Series of {FeNO}8, {FeNO}7, and {FeNO}6 Complexes Stabilized by a Tetracarbene Macrocycle
, 2016 Use of a macrocyclic tetracarbene ligand, which is topologically reminiscent of tetrapyrrole macrocycles though electronically distinct, has allowed for the isolation, X-ray crystallographic characterization and comprehensive spectroscopic investigation ...
Serena DeBeer (1325124) +4 more
core +1 more source
Environmental Toxicology, EarlyView.ABSTRACT Sargassum inundation of Caribbean and American shorelines is a growing environmental hazard. Hydrogen sulfide (H2S) and ammonia (NH3) produced by decomposing Sargassum could be involved in airway obstruction and bronchial inflammation. The study was undertaken to evaluate the effects of exposure to H2S and NH3 gases emitted during Sargassum ...
Rishika Banydeen +9 more
wiley +1 more source
Acta Scientiarum: Animal Sciences, 2007 O trabalho teve como objetivo avaliar o tratamento do feno de grama-estrela(Cynodon nlemfuensis Vanderyst) com uréia sobre a digestibilidade da dieta em ovinos. Osfenos foram tratados com uréia na proporção de 2, 4 e 6% com base na MS.
Moisés Calixto Júnior +3 more
doaj +1 more source