Results 111 to 120 of about 20,294 (238)

Revisiting Platelet‐Activating Factor in Asthma: An Exploratory Metabolomics Analysis of PAF C‐18:1 and Type 2 Inflammation

Allergy, EarlyView.
Noeul Kang, Young Jin Pyung, Deog Kyeom Kim, Cheol‐Heui Yun, Hyun Woo Lee   +4 more
wiley   +1 more source

Physical activity partly inhibits autonomic imbalance, immune dysfunction and quality of life induced by chronic shiftwork in policemen

Experimental Physiology, EarlyView.
Abstract Chronic shiftwork can impair autonomic cardiovascular regulation and immune homeostasis. However, the interaction between occupational status and physical activity level in military police officers remains incompletely understood. This cross‐sectional factorial study included 102 men stratified according to occupational status and physical ...
Hélida C. Aquino‐Santos, Jeanne S. Tavares‐Vasconcelos, Anamei Silva‐Reis, Maysa A. R. Brandão‐Rangel, Rayssa T. Morais‐Felix, Fernando A. Santa‐Rosa, André L. L. Bachi, Viviane Soares, Omid Salehian, Claudio R. Frison, Rodolfo P. Vieira, Regiane Albertini   +11 more
wiley   +1 more source

No Effect of Preoperative Mepolizumab on Early Postoperative Healing After ESS for Severe CRSwNP

Laryngoscope Investigative Otolaryngology, Volume 11, Issue 6, December 2026.
ABSTRACT Objective To evaluate postoperative endoscopic mucosal healing 2 weeks after ESS in patients with severe CRSwNP treated with surgery alone versus surgery combined with biologics initiated 2 weeks preoperatively. Methods In this exploratory post hoc analysis, patients with severe CRSwNP were divided into two cohorts: ESS alone and ESS with ...
A. S. Homøe, M. Høxbro, J. Tidemandsen, V. Backer, E. Kiaer, S. Scott, N. Rubek, K. Aanæs   +7 more
wiley   +1 more source

% difference of FENO after MDP challenge by baseline FENO, asthma, atopy and BHR severity.

, 2013
Abbreviations: FENO, fractional exhaled nitric oxide; MDP, mannitol dry powder; BHR, bronchial hyperresponsiveness; SPT, skin prick test. Baseline FENO defined as tertiles (low levels: 30 ppb).
Daniel Trachsel (287960), Juerg Hammer (287962), Juerg Barben (287959), Barbara Schiller (287961), Marie-Pierre F. Strippoli (164187), Claudia E. Kuehni (105404)   +5 more
core   +1 more source

Therapies for Cardiovascular‐Kidney‐Liver‐Metabolic Syndrome: Reappraisal of Fibrates

Diabetes, Obesity and Metabolism, Volume 28, Issue 12, Page 10931-10949, December 2026.
ABSTRACT Cardiovascular disease, chronic kidney disease (CKD), type 2 diabetes mellitus (T2DM), obesity and metabolic dysfunction‐associated steatohepatitis (MASH) frequently coexist and share overlapping pathophysiology, forming the proposed cardiovascular‐kidney‐liver‐metabolic (CKLM) syndrome.
Virginia Anagnostopoulou, Christoforos K. Travlos, Lucas Lage Marinho, Thomas A. Mavrakanas, João Pedro Ferreira, Abhinav Sharma   +5 more
wiley   +1 more source

Assessing the suitability of Fractional Exhaled Nitric Oxide (FENO) cut-off ranges for aboriginal and/or Torres Strait Islander children and young adults

, 2018
Introduction/Aim Fractional exhaled nitric oxide (FeNO) is used as a non‐invasive measure of eosinophilic airway inflammation. It is unknown how appropriate the recommended FeNO cut‐off ranges are for Aboriginal and/or Torres Strait Islander patients ...
Chang, A, Mcelrea, M, Petsky, H, Blake, T, Chatfield, M   +4 more
core   +1 more source

Bronchial Responsiveness Is Related to Increased Exhaled NO (FENO) in Non-Smokers and Decreased FENO in Smokers [PDF]

, 2012
Rationale Both atopy and smoking are known to be associated with increased bronchial responsiveness. Fraction of nitric oxide (NO) in the exhaled air (FENO), a marker of airways inflammation, is decreased by smoking and increased by atopy.
Torén, Kjell, Christer Janson (83414), Dan Norbäck (2143342), Högman, Marieann,, Olin, Anna-Carin, Norbäck, Dan,, Dan Norbäck, Anna-Carin Olin (168124), Kjell Torén (168121), Christer Janson, Norbäck Dan, Rolla, Giovanni, Janson, Christer, Norbäck, Dan, Giovanni Rolla (168117), Janson, Christer,, Janson Christer, Högman, Marieann, Marieann Högman (168114), Andrei Malinovschi (168111), Olin Anna-Carin, Malinovschi Andrei, Torén Kjell, Malinovschi, Andrei, Rolla Giovanni, Högman Marieann, Marieann Högman, Kjell Torén, Andrei Malinovschi, Giovanni Rolla, Malinovschi, Andrei,, Anna-Carin Olin   +31 more
core   +1 more source

Pharmacokinetics and safety of tezepelumab in children with mild, moderate or severe asthma and adolescents with mild‐to‐moderate asthma

British Journal of Clinical Pharmacology, Volume 92, Issue 11, Page 3819-3830, November 2026.
Abstract Aim Tezepelumab is a human monoclonal antibody that blocks the activity of thymic stromal lymphopoietin and is approved for adolescents and adults with severe asthma. This analysis assessed pharmacokinetics (PK), pharmacodynamics and safety of tezepelumab up to 85 days postdose in adolescents and children.
Anna Lundahl, Jonathan Grigg, Lubna Abuqayyas, Piotr Kuna, Gillian Hunter, Beata Pawlikowska, Jacob Leander, Michael Levin, Atul Gupta, James Paton, Katharine C. Pike, Jane R. Parnes, Gun Almqvist, Stephanie L. Roseti, on behalf of the study investigators   +14 more
wiley   +1 more source

Relationship Between Bronchodilator Reversibility and Spirometry Response to Dupilumab in Type 2 High Uncontrolled Severe Asthma

Clinical &Experimental Allergy, Volume 55, Issue 3, Page 253-255, March 2025.
Robert Greig, Kirsten Stewart, Chris RuiWen Kuo, Rory Chan, Brian Lipworth   +4 more
wiley   +1 more source

Time‐of‐Day Variation in Airway Hyperresponsiveness in Asthma: Potential Circadian Mechanisms and Translational Implications

Clinical and Translational Allergy, Volume 16, Issue 11, November 2026.
Graphical abstract Biological time, time‐dependent airway hyperresponsiveness, and clinical translation. The external day–night cycle entrains the central clock in the suprachiasmatic nucleus and peripheral pulmonary clocks, whereas sleep and activity, posture, environmental exposures, and medication timing modify the airway state observed at a given ...
Chang Zhou, Xinyue Hu, Lijuan Zeng, Yi Tang, Chuxian Yi, Guomin Zhang, Sujuan Peng   +6 more
wiley   +1 more source