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Update on the Role of FeNO in Asthma Management
Diagnostics, 2023 Asthma is a heterogenous disorder characterized by presence of different phenotypes and endotypes. Up to 10% of the individuals suffer from severe asthma and are at increased risk of morbidity and mortality. Fractional exhaled nitric oxide (FeNO) is a cost-effective, point of care biomarker that is used to detect type 2 airway inflammation.
Muhammad Adrish +2 more
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Seminars in Respiratory and Critical Care Medicine, 2022
AbstractAsthma is a common disease affecting 350 million people worldwide, which is characterized by airways inflammation and hyperreactivity. Historically diagnosis and treatment have been mainly based on symptoms, which have the potential to result in misdiagnosis and inappropriate treatment.
Lola, Loewenthal, Andrew, Menzies-Gow
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AbstractAsthma is a common disease affecting 350 million people worldwide, which is characterized by airways inflammation and hyperreactivity. Historically diagnosis and treatment have been mainly based on symptoms, which have the potential to result in misdiagnosis and inappropriate treatment.
Lola, Loewenthal, Andrew, Menzies-Gow
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A pathophysiological approach for FeNO: A biomarker for asthma
Allergologia Et Immunopathologia, 2015 The present review is focused on literature concerning the relevance of fractional exhaled nitric oxide (FeNO) in clinical practice from a pathophysiological point of view. There is increasing evidence that asthma is a heterogeneous pathological condition characterised by different phenotypes/endotypes related to specific biomarkers, including FeNO ...
Giorgio Ciprandi +1 more
exaly +3 more sources
FeNO as biomarker for asthma phenotyping and management
Allergy and Asthma Proceedings, 2015The current review aims to revisit literature on exhaled nitric oxide (FeNO) in asthma phenotyping and management to clarify the utility of this test in clinical practice. It is increasingly evident that multiple profiles characterize asthma as a complex disease for which is necessary to find tools able to discriminate among these phenotypes to achieve
Giorgio Ciprandi +2 more
exaly +3 more sources
Correlation between the FeNO Angle and d−p Mixing in {FeNO}7 Complexes
Inorganic Chemistry, 2011The great majority of low-spin {FeNO}(7) complexes exhibit FeNO angles of around 140-145°, whereas a small handful are characterized by linear FeNO units. Conspicuously absent are intermediate FeNO angles of 150-170°. Spurred by the recent observation of such an angle in a square-pyramidal {FeNO}(7) complex, we carried out a density functional theory ...
Jeanet, Conradie, Abhik, Ghosh
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Methacholine and FeNO Measurement in Patients with Habit Cough
Klinische Pädiatrie, 2023Abstract Background Chronic cough is one of the most common symptoms in childhood. Making a definite diagnosis is a challenge for all pediatricians especially in patients when cough is without an organic cause like in habit cough.
Sandra Woelke +7 more
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One Electron Makes Differences: From Heme {FeNO}7 to {FeNO}8
Angewandte Chemie, 2015AbstractThe first X‐ray single‐crystal structure of a {FeNO}8 porphyrin complex [Co(Cp)2][Fe(TFPPBr8)(NO)], and the structure of the {FeNO}7 precursor [Fe(TFPPBr8)(NO)] are determined at 100 K. The two complexes are also characterized by FTIR and UV/Vis spectroscopy.
Bin, Hu, Jianfeng, Li
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Tidal breathing FeNO measurements: A new algorithm
Pediatric Pulmonology, 2012AbstractObjectiveInternational guidelines recommend measuring fractional exhaled nitric oxide (FeNO) during a single slow exhalation with a constant flow of 50 ml/sec. We developed a new algorithm to compute FeNO at 50 ml/sec from tidal breathing measurements.
Mastrigt, Esther +5 more
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Using FeNO in the diagnosis and management of asthma
British Journal of Nursing, 2014Being able to identify inflammation of the lung through the measurement of nitric oxide is an excellent new way to assist in the accurate diagnosis of asthma and to monitor the effectiveness of asthma medication. An accurate reading can be taken in minutes and the technology will assist in a correct diagnosis. This increases patient confidence from the
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JBIC Journal of Biological Inorganic Chemistry, 2007
A density functional theory account of the changes in FeNO bonding that occur in response to both bonded and nonbonded structural perturbations is reported for a series of {FeNO}(6) heme-thiolate model complexes. Using [Fe(porphine)(SCH(3))NO] as the reference complex, we constructed models to mimic equatorial (cis), distal, and proximal influences of ...
Douglas P, Linder, Kenton R, Rodgers
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A density functional theory account of the changes in FeNO bonding that occur in response to both bonded and nonbonded structural perturbations is reported for a series of {FeNO}(6) heme-thiolate model complexes. Using [Fe(porphine)(SCH(3))NO] as the reference complex, we constructed models to mimic equatorial (cis), distal, and proximal influences of ...
Douglas P, Linder, Kenton R, Rodgers
openaire +2 more sources