Results 51 to 60 of about 9,926 (208)
Effect of Dupilumab on Airway Inflammation in Patients With Persistent Asthma
Allergy, EarlyView.EXPEDITION (NCT02573233) assessed the effects of dupilumab on airway inflammation in patients with persistent asthma using bronchoscopy and gene expression analysis. Dupilumab showed no appreciable effect on inflammatory cell types in biopsies or BALF samples.
Michael E. Wechsler +22 more
wiley +1 more source
Ciência Animal Brasileira, 2011 Objetivou-se avaliar o consumo de nutrientes e o balanço hídrico em equinos em mantença, alimentados com fenos convencionais. Utilizaram-se seis equinos machos com idade média de nove anos e PV de 361,16 ± 12 kg, em delineamento quadrado latino (6x6 ...
Leonir Bueno Ribeiro +5 more
doaj +1 more source
The utility of measuring FENO in monitoring asthmatic children
Romanian Journal of Pediatrics, 2014 Purposes and objectives. Bronchial asthma is the most frequent chronic disease in children and in almost 50% of these cases, it occurs eosinophilic airway inflammation. The most important objective in monitoring asthma is preventing exacerbations by means of good communication between physician, patient and family, a good compliance of the latter and ...
Cristina Popescu, Mihai Craiu
openaire +2 more sources
Allergy, EarlyView.We aimed to characterise Alternaria sensitisation trajectories from childhood to adulthood; we compared SPT, whole‐extract sIgE and rAlt a 1, and assessed their longitudinal association with asthma and rhinitis in the Isle of Wight birth cohort. Alternaria sensitisation in the Isle of Wight Birth Cohort emerges mainly in late adolescence and, when ...
Mohammad Leily +7 more
wiley +1 more source
Lack of Association between Inhaled Corticosteroid Use Based on the Exhaled Nitric Oxide and Acute Exacerbation of Chronic Obstructive Pulmonary Disease [PDF]
Tuberculosis and Respiratory DiseasesBackground Fractional exhaled nitric oxide (FeNO) is known to useful biomarker for detecting eosinophilic airway inflammation. However, there is a lack of evidence regarding the role of FeNO in chronic obstructive pulmonary disease (COPD).
Bo-Guen Kim +4 more
doaj +1 more source
Serotonin Degradation and Lipid Metabolism Regulate Human Tc2 Cell Effector Functions
Allergy, EarlyView.Human Tc2 cells exhibit a metabolically active phenotype characterized by enhanced glycolysis, mitochondrial respiration, and fatty acid uptake dependent on PPARγ. Alarmins strongly amplify IL‐5 and IL‐13 production in Tc2 cells, supporting a shared immunometabolic program across type 2 lymphocytes.
Sabrina de Souza Ferreira +13 more
wiley +1 more source
Remission in Global Airway Diseases: EUFOREA Consensus Paper
Allergy, EarlyView.ABSTRACT The therapeutic goal in chronic airway diseases is shifting from symptom control to disease remission. Disease‐modifying therapies, including biologics and allergen immunotherapy, have made remission achievable in patients with severe asthma, chronic rhinosinusitis with nasal polyps (CRSwNP), or allergic rhinitis (AR).
J. Christian Virchow +22 more
wiley +1 more source
FeNO and Asthma Treatment in Children
Medicine, 2015 Traditional asthma treatments are typically adjusted in children with asthma using symptoms and spirometry. Treatments tailored in accordance to inflammatory markers, such as fraction of exhaled nitric oxide (FeNO) or sputum eosinophils, are increasing in use.
Lu, Min +4 more
openaire +2 more sources
Clinical Features of Cellular Senescence Pathways in Severe Asthma
Allergy, EarlyView.In bronchial biopsies, SASP and p53 pathway enrichment scores are elevated in severe asthma versus non‐severe asthma and healthy controls. SASP enrichment is validated in the independent NOVA cohort. SASP enrichment is also elevated in nasal brushings of participants with nasal polyps, independently of asthma status.
Woo‐Jung Song +122 more
wiley +1 more source