Results 141 to 150 of about 153,817 (339)

Cost–benefit analysis and ‘next best’ methods to evaluate the efficiency of social policies: As in pitching horseshoes, closeness matters

Annals of Public and Cooperative Economics, EarlyView.
Abstract Many policymakers are unwilling, or think that it is infeasible, to perform comprehensive cost–benefit analysis (CBA) of programmes in social policy arenas. What principles actually underlie CBA? An understanding is necessary to assess whether other evaluation methods are close enough to CBA to provide useful information on social efficiency ...
Aidan R. Vining, Anthony E. Boardman
wiley   +1 more source

Strategies used to reduce harms associated with fentanyl exposure among rural people who use drugs: multi-site qualitative findings from the rural opioid initiative

Harm Reduction Journal
Aim Illicitly manufactured fentanyl and its analogs are the primary drivers of opioid overdose deaths in the United States (U.S.). People who use drugs may be exposed to fentanyl or its analogs intentionally or unintentionally.
Suzan M. Walters, Robin Baker, David Frank, Monica Fadanelli, Abby E. Rudolph, William Zule, Rob J. Fredericksen, Rebecca Bolinski, Adams L. Sibley, Vivian F. Go, Lawrence J. Ouellet, Mai T. Pho, David W. Seal, Judith Feinberg, Gordon Smith, April M. Young, Thomas J. Stopka   +16 more
doaj   +1 more source

Effect of epidural saline washout on regression of sensory and motor block after epidural anaesthesia with 2% lidocaine and fentanyl in elderly patients

, 2009
E. Y. Park, Hae Keum Kil, W. S. Park, Nigel Lee, J.‐Y. Hong   +4 more
openalex   +2 more sources

Toxicokinetic modelling of the synthetic cannabinoid 5F‐MDMB‐P7AICA and its main metabolite in pigs following pulmonary administration

British Journal of Clinical Pharmacology, EarlyView.
Aims Since their emergence on the drug market, synthetic cannabinoids (SC) are still gaining increasing importance in forensic toxicology. The representatives of the so‐called new psychoactive substances have in common that they have not undergone preclinical safety studies. Hence, knowledge on toxicokinetic (TK) data is sparse.
Adrian A. Doerr, Christiane Dings, Omar Zaher, Frederike Nordmeier, Nadja Walle, Matthias W. Laschke, Michael D. Menger, Peter H. Schmidt, Markus R. Meyer, Thorsten Lehr, Nadine Schaefer   +10 more
wiley   +1 more source

Developing a Co‐Designed Strategy to Improve Labor Monitoring and Management in India Using the World Health Organization Labour Care Guide: A Mixed‐Methods Formative Study

Birth, EarlyView.
ABSTRACT Introduction Nearly half of all perinatal deaths occur during the intrapartum period due to inadequate labor monitoring and intervention. The partograph, a paper‐based labor monitoring tool, can assist providers in recognizing and acting on early signs of fetal–maternal distress if used effectively. In 2020, the World Health Organization (WHO)
Elizabeth Armari, Sunil S. Vernekar, Yeshita Pujar, Veronica Pingray, Fernando Althabe, Luz Gibbons, Mabel Berrueta, Alvaro Ciganda, Rocio Rodriguez, Jayashree Ashok Kumar, Shruti Bhavi Patil, Aravind Karinagannanavar, Raveendra R. Anteen, Pavithra M. R., Savitri Bendigeri, Shukla Shetty, B. Latha, Megha H. M., Suman S. Gaddi, Shaila Chikkagowdra, Bellara Raghavendra, Caroline S. E. Homer, Manjunath Somannavar, Shivaprasad S. Goudar, Joshua P. Vogel   +24 more
wiley   +1 more source

Efficacy and safety of a generic remifentanil formulation versus fentanyl and Ultiva during general anaesthesia: A phase III, prospective, multi-centric, observer-blind, randomised controlled trial. [PDF]

Indrani Hemantkumar, Ashok Kumar Swain, Manjaree Mishra, Swati Singh, C. L. Gurudatt, Janampet Bekkam Giridhar   +5 more
openalex   +1 more source

Leveraging the ADAM10 prodomain for selective inhibition to enhance recovery after myocardial infarction

British Journal of Pharmacology, EarlyView.
Background and Purpose Inflammation plays a crucial role in the development and progression of numerous acute and chronic diseases such as myocardial infarction (MI) and heart failure. Targeting ADAM proteases, particularly ADAM10, holds promise for fine‐tuning inflammatory responses.
Erik Klapproth, Johanna Marks, Patrick Diaba‐Nuhoho, Sören Grell, Paul Leubauer, Susanne Kämmerer, Johannes R. Soltwedel, Fred Rasmussen, Felix Mejia, Marcia L. Moss, Christopher Prince, Peter Mirtschink, Ben Wielockx, Paul Saftig, Michael Wagner, Kristina Lorenz, Ali El‐Armouche   +16 more
wiley   +1 more source

Case Series: Magnitude and duration of fentanyl and xylazine detection in the urine of persons with opioid use disorder [PDF]

Helen Bird, William Clarke, Craig W. Hendrix, Kelly E. Dunn, Andrew S. Huhn   +4 more
openalex   +1 more source

Divergence in μ and δ opioid receptor pharmacology in neurons and antinociceptive efficacy in neuropathic pain: Insights from MP135 and CYM51010

British Journal of Pharmacology, EarlyView.
Background and purpose Opioids targeting the μ opioid receptor remain largely ineffective in neuropathic pain conditions, emphasizing the need for novel therapeutic strategies. MP135 was reported to reduce thermal nociception in naive animals by activating μ‐δ opioid receptor heteromers.
Perrine Inquimbert, Chantal Fitterer, Sylvain Hugel, Mila Jesic, Yannick Goumon, Virgine Andry, Severine Schneider, Francois Daubeuf, Abdelfattah Faouzi, Stephane Doridot, Susruta Majumdar, Frederic Bihel, Martine Schmitt, Dominique Massotte   +13 more
wiley   +1 more source

Subarachnoid clonidine or fentanyl with low dose hyperbaric bupivacaine for elective caesarean section - A comparative study

, 2012
Md. Manowarul Islam, Nadeem Parvez Ali, Rabeya Begum, AKM Akhtaruzzaman   +3 more
openalex   +2 more sources