Local cortical dynamics of burst suppression in the anaesthetized brain [PDF]
, 2013 Burst suppression is an electroencephalogram pattern that consists of a quasi-periodic alternation between isoelectric ‘suppressions’ lasting seconds or minutes, and high-voltage ‘bursts’. It is characteristic of a profoundly inactivated brain, occurring
Brown, Emery N. +7 more
core +1 more source
The impacts and service responses to injecting cathinones and novel opioids amongst marginalized drug using populations – a scoping review [PDF]
, 2022 Background: A growing body of literature reports on the injection of synthetic cathinones (SC) and novel synthetic opioids (NSO) in marginalized drug-using (MDU) populations.
Henriques, S. +3 more
core +3 more sources
Functional physico-chemical, ex vivo permeation and cell viability characterization of omeprazole loaded buccal films for pediatric drug delivery [PDF]
, 2016 Buccal films were prepared from aqueous and ethanolic Metolose gels using the solvent casting approach (40 °C). The hydration (PBS and simulated saliva), mucoadhesion, physical stability (20 °C, 40 °C), in vitro drug (omeprazole) dissolution (PBS and ...
Boateng, Joshua +2 more
core +2 more sources
“It wasn’t here, and now it is. It’s everywhere": fentanyl’s rising presence in Oregon’s drug supply
Harm Reduction Journal, 2022 Background Illicit fentanyl has contributed to a drastic increase in overdose drug deaths. While fentanyl has subsumed the drug supply in the Northeastern and Midwestern USA, it has more recently reached the Western USA.
Sarah S. Shin +14 more
doaj +1 more source
Short term doxycycline treatment induces sustained improvement in myocardial infarction border zone contractility. [PDF]
, 2018 Decreased contractility in the non-ischemic border zone surrounding a MI is in part due to degradation of cardiomyocyte sarcomeric components by intracellular matrix metalloproteinase-2 (MMP-2).
Aguayo, Esteban +11 more
core +2 more sources
Responding to a surge in overdose deaths: perspectives from US syringe services programs
Harm Reduction Journal, 2022 Background US overdose deaths have reached a record high. Syringe services programs (SSPs) play a critical role in addressing this crisis by providing multiple services to people who use drugs (PWUD) that help prevent overdose death.
Madeline C. Frost +15 more
doaj +1 more source
Advances in oral transmucosal drug delivery [PDF]
, 2011 Original article can be found at : http://sciencedirect.com/ Copyright ElsevierThe successful delivery of drugs across the oral mucosa represents a continuing challenge, as well as a great opportunity.
Brown, Marc +2 more
core +1 more source
Effects of mild hypothermia on hemodynamics in cardiac arrest survivors and isolated failing human myocardium [PDF]
, 2010 Post-cardiac arrest myocardial dysfunction is a common phenomenon after return of spontaneous circulation (ROSC) and contributes to hemodynamic instability and low survival rates after cardiac arrest.
Anja Pax +9 more
core +2 more sources
Oxidative and pre-inflammatory stress in wedge resection of pulmonary parenchyma using the radiofrequency ablation technique in a swine model [PDF]
, 2012 Background Radiofrequency ablation (RFA) is a thermal energy delivery system used for coagulative cellular destruction of small tumors through percutaneous or intraoperative application of its needle electrode to the target area, and for assisting ...
Theodoros Karaiskos +5 more
core +2 more sources