Results 101 to 110 of about 2,478,172 (300)

Combating Inflammation and Promoting Anabolism in Osteoarthritic Cartilage Defect With an MMP13‐Sensing Dual‐Drug Scaffold

Advanced Science, EarlyView.
ABSTRACT Osteoarthritis (OA) is a widespread degenerative joint condition marked by progressive cartilage breakdown, and a chronic inflammatory microenvironment, where conventional therapies largely fail to halt disease progression. To address this unmet need, an intra‐articularly implantable, disease‐responsive scaffold was developed for combinatorial
Zhen Zhang, Bangheng Liu, Yulei Mu, Huiqun Zhou, Liang Ma, Chenjie Xu, Dong‐An Wang   +6 more
wiley   +1 more source

Innate Immunocompetent hiPSC‐Derived Neurospheroids Capture Early CNS Responses to rAAV

Advanced Science, EarlyView.
Knowledge of human CNS immune responses to AAV‐based gene therapies remains limited due to the lack of immune‐competent human models. Here, a hiPSC‐derived 3D neuroimmune platform integrating neurospheroids and microglia is established using stirred‐tank bioreactors.
Catarina M. Gomes, Gabriela Silva, Mafalda Aleixo, Marta Gomes, Daniel Simão, Stephan J. Holtkamp, Diana D. Lobo, Pradeep Harish, Rosalind Jenkins, Lekh N. Dahal, Rui J. Nobre, Luís de Pereira de Almeida, Mark Trautwein, Paula M. Alves, Catarina Brito   +14 more
wiley   +1 more source

An optimized, rhamnolipid-containing cell-free filtrate from Pseudomonas aeruginosa 8–7 exhibits broad-spectrum antifungal activity and exceptional environmental stability

Frontiers in Plant Science
IntroductionThe biocontrol strain Pseudomonas aeruginosa 8-7 (PA8-7) produces antimicrobial metabolites, yet its application is limited by low yield and insufficiently characterized environmental stability.MethodsFermentation was optimized through medium
Li-ming Dai, Li-li He, Yue-ye Deng, Lan-lan Li, Yi-xian Liu, Yu-ping Shi, Zhi-ying Cai   +6 more
doaj   +1 more source

Activity of Zymomonas mobilis on ethanol products made of cashew nut apple (Anacardium occidentale) with different sources of nitrogen [PDF]

, 2009
Mustofa A, Suranto. 2009. Activity of Zymomonas mobilis on ethanol production made of cashew nut apple (Anacardium occidentale) with different sources of nitrogen. Nusantara Bioscience 1: 105-109.
SURANTO,, MUSTOFA, AKHMAD
core  

Targeted Restoration of the Microbial Tryptophan Oxidative Pathway Ameliorates Autism‐Like Behavioral and Synaptic Deficits

Advanced Science, EarlyView.
ABSTRACT Autism Spectrum Disorder (ASD) is associated with gut microbiota dysbiosis, yet the contribution of specific microbial metabolic pathways remains unclear. Reanalysis of a public ASD cohort revealed reduced functional potential in microbial tryptophan oxidative metabolism.
Rui Guo, Caian He, Xiao Xiao, Jingmeng Li, Zilong Zhang, Ying He, Chuanchuan Wang, Jiale Zhao, Jun Gong, Jiarui Liang, Tian Yuan, Haiting Sun, Xuebo Liu, Chao Gao, Zhigang Liu   +14 more
wiley   +1 more source

Effects of Composite Starter Cultures on Microbial Succession, Quality Characteristics and Flavor Profile of Air-Dried Mutton

Foods
Air-dried mutton is a traditional, culturally significant meat product, yet its spontaneous fermentation is inherently constrained by unstable microbial communities, leading to batch-to-batch quality inconsistency and potential food safety hazards ...
Jiaqi Zhang, Lina Sun, Erke Sun, Shiqi Hao, Hongbo Qu, Yanrong Chen, Weiqi Qin, Ye Jin, Lihua Zhao, Xueying Sun   +9 more
doaj   +1 more source

Engineering Microbial Particles for Next‐Generation Biomedical Platforms

Advanced Science, EarlyView.
Microbe‐derived particles (MDPs), which include extracellular vesicles, outer membrane vesicles, inclusion bodies, polysaccharide particles, and virus‐like particles, represent a rapidly expanding category of bioinspired nanomaterials. With their natural origin, intrinsic biocompatibility, and highly programmable functionality, MDPs serve as a ...
Yuting Li, Yunjie Lu, Ziyan Huang, Jianjiang Chen, Yanbin Liu, Lei Qin, Chao Wang, Yumin Wu   +7 more
wiley   +1 more source

Artificial Intelligence in Yeast Biotechnology: Applications, Opportunities, and Challenges

Applied Sciences
The adoption of artificial intelligence (AI) has been steadily growing across various fields in recent years. AI can have significant advantages for industries, including automation, reliable prediction, enhanced process control, and improved efficiency.
Hossein Zakariapour Bahnamiri, Alica Navrátilová, Marek Kovár, Lucia Klongová, Miroslava Požgajová   +4 more
doaj   +1 more source

Single-cell protein production from industrial off-gas through acetate : techno-economic analysis for a coupled fermentation approach

, 2023
Third-generation (3G) biorefineries harnessing industrial off-gases have received significant attention in the transition towards a sustainable circular economy.
De Winter, Karel, Petrides, Demetri, Kontovas, Stoilas-Stylianos, Soetaert, WimLA258000000275620000-0002-7312-1941F32CB1B2-F0ED-11E1-A9DE-61C894A0A6B4, Vlaeminck, ElodieUGent000140382844802003440506971961715569EDFC4C62-2010-11E4-8BB4-A9F3B4D1D7B1, Uitterhaegen, Evelien, Quataert, Koen, Delmulle, TomCA05LA250000905221178020018743580000-0002-5374-298624E451EC-F0EE-11E1-A9DE-61C894A0A6B4, Ferreira, Rafael G., Misailidis, Nikiforos   +9 more
core  

Harnessing Phase Separation for the Development of High‐Performance Hydrogels

Advanced Science, EarlyView.
ABSTRACT Hydrogels are indispensable for the development of next‐generation bioelectronics, soft robotics, and biomedical devices, where their mechanical properties determine performance and reliability. Among strategies to enhance hydrogel mechanics, phase separation enables controlled heterogeneity resulting in gel networks that are reinforced by ...
Yue Shao, Yiming Ma, Baihao Shao, Molly M. Stevens   +3 more
wiley   +1 more source