Results 1 to 10 of about 20,184 (214)

Nanomechanical Study of Enzyme: Coenzyme Complexes: Bipartite Sites in Plastidic Ferredoxin-NADP⁺ Reductase for the Interaction with NADP⁺ [PDF]

Antioxidants, 2022
Plastidic ferredoxin-NADP+ reductase (FNR) transfers two electrons from two ferredoxin or flavodoxin molecules to NADP+, generating NADPH. The forces holding the Anabaena FNR:NADP+ complex were analyzed by dynamic force spectroscopy, using WT FNR and ...
Sandra Pérez-Domínguez, Silvia Caballero-Mancebo, Carlos Marcuello, Marta Martínez-Júlvez, Milagros Medina, Anabel Lostao   +5 more
doaj   +2 more sources

NADP(H) allosterically regulates the interaction between ferredoxin and ferredoxin‐NADP+ reductase [PDF]

FEBS Open Bio, 2019
Ferredoxin‐NADP+ reductase (FNR) in plants receives electrons from ferredoxin (Fd) at the end of the photosynthetic electron transfer chain and converts NADP+ to NADPH. The interaction between Fd and FNR in plants was previously shown to be attenuated by
Yoko Kimata‐Ariga, Yutaro Chikuma, Takashi Saitoh, Masayuki Miyata, Yuetsu Yanagihara, Kazukiyo Yamane, Toshiharu Hase   +6 more
doaj   +2 more sources

A STD-NMR Study of the Interaction of the Anabaena Ferredoxin-NADP+ Reductase with the Coenzyme [PDF]

Molecules, 2014
Ferredoxin-NADP+ reductase (FNR) catalyzes the electron transfer from ferredoxin to NADP+ via its flavin FAD cofactor. To get further insights in the architecture of the transient complexes produced during the hydride transfer event between the enzyme ...
Lara V. Antonini, José R. Peregrina, Jesús Angulo, Milagros Medina, Pedro M. Nieto   +4 more
doaj   +2 more sources

Identification of Inhibitors Targeting Ferredoxin-NADP+ Reductase from the Xanthomonas citri subsp. citri Phytopathogenic Bacteria [PDF]

Molecules, 2017
Ferredoxin-NADP(H) reductases (FNRs) deliver NADPH or low potential one-electron donors to redox-based metabolism in plastids and bacteria. Xanthomonas citri subsp.
Marta Martínez-Júlvez, Guillermina Goñi, Daniel Pérez-Amigot, Rubén Laplaza, Irina Alexandra Ionescu, Silvana Petrocelli, María Laura Tondo, Javier Sancho, Elena G. Orellano, Milagros Medina   +9 more
doaj   +2 more sources

Design and Synthesis of Chalcone Derivatives as Inhibitors of the Ferredoxin — Ferredoxin-NADP+ Reductase Interaction of Plasmodium falciparum: Pursuing New Antimalarial Agents [PDF]

Molecules, 2014
Some chalcones have been designed and synthesized using Claisen-Schmidt reactions as inhibitors of the ferredoxin and ferredoxin-NADP+ reductase interaction to pursue a new selective antimalaria agent.
Hery Suwito, Jumina, Mustofa, Pratiwi Pudjiastuti, Much Zaenal Fanani, Yoko Kimata-Ariga, Ritsuko Katahira, Toru Kawakami, Toshimichi Fujiwara, Toshiharu Hase, Hasnah Mohd Sirat, Ni Nyoman Tri Puspaningsih   +11 more
doaj   +2 more sources

A bacterial effector protein targets plant ferredoxin-NADP+ reductase to promote infection. [PDF]

PLoS Pathogens
Pathogenic bacteria utilize a type III secretion system to translocate effector proteins into plant cells, where they inhibit plant immunity or interfere with normal cellular functions to facilitate infection.
Lihaitian Wang, Xiaoli Liu, Feng Yu, Wenxuan Pu, Xiaoxu Li, Dousheng Wu   +5 more
doaj   +2 more sources

Characterization of a Unique Pair of Ferredoxin and Ferredoxin NADP⁺ Reductase Isoforms That Operates in Non-Photosynthetic Glandular Trichomes [PDF]

Plants
Our recent investigations indicated that isoforms of ferredoxin (Fd) and ferredoxin NADP+ reductase (FNR) play essential roles for the reductive steps of the 2C-methyl-D-erythritol 4-phosphate (MEP) pathway of terpenoid biosynthesis in peppermint ...
Joshua T. Polito, Iris Lange, Kaylie E. Barton, Narayanan Srividya, B. Markus Lange   +4 more
doaj   +2 more sources

The FinR-regulated essential gene fprA, encoding ferredoxin NADP+ reductase: Roles in superoxide-mediated stress protection and virulence of Pseudomonas aeruginosa. [PDF]

PLoS ONE, 2017
Pseudomonas aeruginosa has two genes encoding ferredoxin NADP(+) reductases, denoted fprA and fprB. We show here that P. aeruginosa fprA is an essential gene.
Siriwan Boonma, Adisak Romsang, Jintana Duang-Nkern, Sopapan Atichartpongkul, Wachareeporn Trinachartvanit, Paiboon Vattanaviboon, Skorn Mongkolsuk   +6 more
doaj   +2 more sources

Inhibitory Activity and Docking Analysis of Antimalarial Agents from Stemona sp. toward Ferredoxin-NADP+ Reductase from Malaria Parasites [PDF]

Journal of Parasitology Research, 2018
Ferredoxin-NADP+ reductases (FNRs, EC 1.18.1.2) were found in the plastids of Plasmodium and have been considered as a target for the development of new antimalarial agents.
Pratiwi Pudjiastuti, Ni Nyoman T. Puspaningsih, Imam Siswanto, Much. Z. Fanani, Yoko K. Ariga, Toshiharu Hase, Satyajit D. Sarker, Lutfun Nahar   +7 more
doaj   +2 more sources

Pseudomonas aeruginosa IscR-Regulated Ferredoxin NADP(+) Reductase Gene (fprB) Functions in Iron-Sulfur Cluster Biogenesis and Multiple Stress Response. [PDF]

PLoS ONE, 2015
P. aeruginosa (PAO1) has two putative genes encoding ferredoxin NADP(+) reductases, denoted fprA and fprB. Here, the regulation of fprB expression and the protein's physiological roles in [4Fe-4S] cluster biogenesis and stress protection are ...
Adisak Romsang, Jintana Duang-Nkern, Wilaiwan Wirathorn, Paiboon Vattanaviboon, Skorn Mongkolsuk   +4 more
doaj   +2 more sources