Results 31 to 40 of about 929,917 (139)

Phototriggering Nitric Oxide Synthase from Geobacillus stearothermophilus [PDF]

, 2012
Nitric oxide synthases (NOS) produce L-citrulline and nitric oxide (NO) in two turnovers from L-arginine via the bound intermediate, N-hydroxy-L-arginine.
Keller, Gretchen Eva, Gretchen Eva Keller   +1 more
core   +1 more source

Symptomatic severe hypophosphatemia after intravenous ferric carboxymaltose

JGH Open, Volume 3, Issue 5, Page 438-440, October 2019., 2019
A 73‐year‐old woman with anemia due to portal hypertensive gastropathy and gastric antral vascular ectasia was hospitalized with severe symptomatic hypophosphatemia and fractures after recurrent ferric carboxymaltose infusions. Asymptomatic hypophosphatemia has been previously described after ferric carboxymaltose in several large trials; however, this
Wendy Fang, Lawrence P McMahon, Stephen Bloom, Mayur Garg   +3 more
wiley   +1 more source

Enhancing effect of saccharated ferric oxide on human lymphocyte transformation in serum-free medium.

The Tohoku Journal of Experimental Medicine, 1982
The effect of saccharated ferric oxide on the response of human peripheral lymphocytes to stimulation by phytohemagglutinin in serum-free medium was studied by measuring the incorporation of [3H]thymidine into DNA. The addition of saccharated ferric oxide resulted in a significant increase in [3H]thymidine uptake not only with mitogen added, but also ...
TANNO, YASUO, TAKISHIMA, TAMOTSU
openaire   +3 more sources

Vitamins in cell culture media: Stability and stabilization strategies

Biotechnology and Bioengineering, Volume 116, Issue 6, Page 1537-1555, June 2019., 2019
The use of chemically‐defined cell culture media in place of serum‐ or hydrolysate‐based media has significantly enhanced the robustness of cell culture in the biomanufacturing of therapeutic proteins. However, some of these essential chemical compounds, such as vitamins, still contribute to cell culture inconsistency via chemical degradation upon ...
Alisa Schnellbaecher, Dennis Binder, Stephanie Bellmaine, Aline Zimmer   +3 more
wiley   +1 more source

Pharmaceutical stability of colloidal saccharated iron oxide injection in normal saline

, 2018
Background Colloidal saccharated iron oxide injection is used for the treatment of iron deficiency anemia in patients with a poor oral intake. Because of the poor stability of the colloid particle, there have been concerns regarding its compatibility ...
Takuya Fujita, Ken-yuh Hasumoto, Serika Matsuoka, Kosuke Shimokawa, Tomonobu Okano, Yusuke Kono, Hiroyuki Kawahara, Asami Suzuki, Mikio Kakumoto, Daiki Hira, Masahide Onoue   +10 more
core   +1 more source

Zeolite protects mice from iron‐induced damage in a mouse model trial

FEBS Open Bio, Volume 8, Issue 11, Page 1773-1781, November 2018., 2018
Zeolites are microporous minerals that are ideally suited to binding metals such as iron within their cagelike structures. We investigated whether the common zeolite clinoptilolite could counter the effects of iron overload. We injected mice in the abdominal cavity with iron and/or clinoptilolite over a period of 30 days.
Xiyong Fan, Chris McLaughlin, Jason Ravasini, Cleo Robinson, Anthony M. George   +4 more
wiley   +1 more source

A meta-analysis of ferric carboxymaltose versus other intravenous iron preparations for the management of iron deficiency anemia during pregnancy

Revista Brasileira de Ginecologia e Obstetrícia
Objective: We conducted a meta-analysis of randomized clinical trials evaluating the clinical effects of ferric carboxymaltose therapy compared to other intravenous iron in improving hemoglobin and serum ferritin in pregnant women.
Sanjay Gupte, Ashis Mukhopadhyay, Manju Puri, P. M. Gopinath, Reena Wani, J. B. Sharma, Onkar C. Swami   +6 more
doaj   +1 more source

Scientific opinion on the tolerable upper intake level for iron

EFSA Journal, Volume 22, Issue 6, June 2024.
Abstract Following a request from the European Commission, the EFSA Panel on Nutrition, Novel Foods and Food Allergens (NDA) was asked to deliver a scientific opinion on the tolerable upper intake level (UL) for iron. Systematic reviews were conducted to identify evidence regarding high iron intakes and risk of chronic diseases, adverse ...
EFSA Panel on Nutrition, Novel Foods and Food Allergens (NDA), Dominique Turck, Torsten Bohn, Jacqueline Castenmiller, Stefaan de Henauw, Karen‐Ildico Hirsch‐Ernst, Helle Katrine Knutsen, Alexandre Maciuk, Inge Mangelsdorf, Harry J. McArdle, Kristina Pentieva, Alfonso Siani, Frank Thies, Sophia Tsabouri, Marco Vinceti, Peter Aggett, Susan Fairweather‐Tait, Agnès de Sesmaisons Lecarré, Lucia Fabiani, Nena Karavasiloglou, Roanne Marie Saad, Angeliki Sofroniou, Ariane Titz, Androniki Naska   +24 more
wiley   +1 more source

Effects of iron infusion on serum iron (A), MDA (B), FMD (C) and GTN-induced vasodilatation (D).

, 2014
Serum iron (A) and MDA levels (B) at baseline, 5 and 20 min after the intravenous saccharated ferric oxide infusion in non-smokers. FMD (C) and GTN-induced vasodilatation (D) before and after the intravenous saccharated ferric oxide injection.
Hidehiro Matsuoka (526127), Seiya Okuda (526128), Sho-ichi Yamagishi (526125), Shuji Iida (526126), Kei Fukami (526124)   +4 more
core   +1 more source

Quality of life improvements in women with uterine fibroids treated with relugolix combination therapy during the LIBERTY long‐term extension study: A descriptive subgroup analysis in women with anemia at baseline

International Journal of Gynecology &Obstetrics, Volume 165, Issue 2, Page 431-441, May 2024.
Abstract Objective To investigate the effects of 52 weeks of treatment with relugolix combination therapy (relugolix 40 mg, estradiol 1 mg, norethindrone acetate 0.5 mg) on symptoms of uterine fibroids (UF) and quality of life (QoL) in women with heavy menstrual bleeding associated with UF and anemia (hemoglobin ≤10.5 g/dL) at baseline.
Roberta Venturella, Andrea S. Lukes, Rui Wu, Rachel McLean, Viatcheslav G. Rakov, Ayman Al‐Hendy   +5 more
wiley   +1 more source