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Impact of the three-fold channel substitution D131N on kinetics of translocation of Fe²⁺ across the protein coat is more severe for human cytosolic H-chain ferritin than for human mitochondrial ferritin.

Dalton Trans
Bugg Z, Hazlewood C, Hemmings AM, Bradley JM, Le Brun NE.   +4 more
europepmc   +1 more source

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New Insights into the Role of Ferritin in Iron Homeostasis and Neurodegenerative Diseases

Molecular Neurobiology, 2021
Junxia Xie, Huamin Xu, Xie Junxia
exaly   +2 more sources

Autophagy promotes ferroptosis by degradation of ferritin

Autophagy, 2016
Wen Hou, Xinxin Song, Michael T Lotze
exaly   +2 more sources

Oligodendrocytes Provide Antioxidant Defense Function for Neurons by Secreting Ferritin Heavy Chain

Cell Metabolism, 2020
Summary An evolutionarily conserved function of glia is to provide metabolic and structural support for neurons. To identify molecules generated by glia and with vital functions for neurons, we used Drosophila melanogaster as a screening tool, and ...
Liliana D Pedro, Maryam K Fard, Klaus-Armin Nave   +2 more
exaly   +2 more sources

Ferritin‐Hijacking Nanoparticles Spatiotemporally Directing Endogenous Ferroptosis for Synergistic Anticancer Therapy

Advances in Materials, 2022
Existing ferroptosis as an iron‐dependent form of regulated cell death primarily relies on importing exogenous iron. However, the excessive employment of toxic materials may cause potential adverse effects on human health.
Luwen Zhu, Yuchan You, Minxia Zhu, Yanling Song, Jucong Zhang, Jiahao Hu, Xinyi Xu, Xiaoling Xu, Yongzhong Du, Jiansong Ji   +9 more
semanticscholar   +1 more source

Serum Ferritin

CRC Critical Reviews in Clinical Laboratory Sciences, 1979
(1) Brief introduction to iron metabolism and the biochemistry of ferritin. (2) Early studies of circulating ferritin. (3) Methods for measuring serum ferritin concentrations -- immunoradiometric, radioimmuno- and enzyme-linked immuno assays based on liver or spleen ferritin -- an evaluation of these techniques.
Mark Worwood, James D. Cook
openaire   +5 more sources

Ferritin: A Multifunctional Nanoplatform for Biological Detection, Imaging Diagnosis, and Drug Delivery.

Accounts of Chemical Research, 2021
ConspectusFerritins are spherical iron storage proteins within cells that are composed of a combination of 24 subunits of two types, heavy-chain ferritin (HFn) and light-chain ferritin (LFn).
Ningning Song, Jianlin Zhang, Jiao Zhai, Juanji Hong, Chang Yuan, Minmin Liang   +5 more
semanticscholar   +1 more source

Ferritin: The role of aluminum in ferritin function

Neurobiology of Aging, 1991
We previously showed that human brain ferritin (HBF) binds aluminum (Al) in vivo and in vitro and HBF isolated from Alzheimer's brain had more Al bound compared to aged matched controls (7). To further understand the role ferritin may play in Al neurotoxicity, we have studied in vitro the effect of Al on the function of human ferritin isolated from ...
J T, Fleming, J G, Joshi
openaire   +2 more sources