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Assessment of serum ferritin as a biomarker in COVID-19: bystander or participant? Insights by comparison with other infectious and non-infectious diseases

Biomarkers, 2020
Background The 2019 coronavirus disease (COVID-19) caused by the SARS-CoV-2 virus has an impact on all aspects of patient care. Serum ferritin generally represents a biomarker of choice when iron deficiency is suspected.
K. Kappert, Amir Jahic, R. Tauber
semanticscholar   +1 more source

Differential localization of ferritin and ferritin immune complexes in the spleen: Influence of the charge of ferritin

Clinical Immunology and Immunopathology, 1986
Prior studies have demonstrated that following administration to animals most antigens (Ag) localize within the red pulp whereas immune complexes (IC) are found in the white pulp. Using ferritin and ferritin IC, we describe a striking different localization of the Ag alone compared with the same AG complexed with its antibody.
C, Genin, A F, Michael
openaire   +2 more sources

A plasma ferritin is not always a serum ferritin

Pathology, 2015
Aim Ferritin is an iron-storage protein with plasma levels used as an indicator of iron deficiency. We undertook parallel testing of ferritin levels in serum and plasma to measure the range of variation and we present data for specimens from a panel of otherwise healthy volunteers.
Yu Ji   +3 more
openaire   +1 more source

Ferritin—a mediator of apoptosis?

Journal of Cellular Physiology, 2007
AbstractPreviously we have demonstrated an apoptosis inducing activity for a rat hepatocyte conditioned medium (CM) presumably mediated by acidic isoferritins. Here, we present support for this assumption since isoferritins purified from different rat hepatocyte CM significantly enhanced the frequency of apoptotic cells in primary rat hepatocytes, an ...
BRESGEN N   +9 more
openaire   +4 more sources

Ferritin: Diversity and Management of Ferritin Measurement Methods

2018
Serum ferritin is one of the most important and widely used markers of iron metabolism, and is a recommended standard index of iron dynamics in guidelines for renal anemia in many countries. However, serum ferritin measurement has several disadvantages.
Daigo, Kamei   +5 more
openaire   +2 more sources

The Ferritin Superfamily

2017
Iron is very important in many biological processes and the ferritin protein family has evolved to store iron and to maintain cellular iron homeostasis. The deletion of the coding gene for the H subunit of ferritin leads to early embryonic death in mice and mutations in the gene for the L subunits in humans has been observed in neurodegenerative ...
openaire   +2 more sources

Ascorbate and ferritin interactions: Consequences for iron release in vitro and in vivo and implications for inflammation

Free Radical Biology & Medicine, 2019
This review discusses the chemical mechanisms of ascorbate‐dependent reduction and solubilization of ferritin's ferric iron core and subsequent release of ferrous iron.
C. Badu-Boateng, R. Naftalin
semanticscholar   +1 more source

Ferritin und Hämosiderin

DMW - Deutsche Medizinische Wochenschrift, 1963
Als Speichereisenfraktionen des Organismus gelten bis heute das Ferritin und das Hamosiderin, Ihr Eisengehalt betragt 1,0 – 1,5 g. Sie finden sich vor allem in Leber, Milz und Knochenmark und stellen das Reservematerial fur die Hamoglobin- und Zellhaminbildung dar.
openaire   +2 more sources

Causes of Ferritin Elevation

JAMA, 2014
Causes of Ferritin Elevation.
openaire   +2 more sources

Ferritin heavy/light chain (FTH1/FTL) expression, serum ferritin levels, and their functional as well as prognostic roles in acute myeloid leukemia

European Journal of Haematology, 2018
We previously reported the prognostic value of serum ferritin in younger patients with intermediate‐risk acute myeloid leukemia (AML). The aims of this study were to confirm this finding in a larger cohort regardless of age and prognostic subgroups, to ...
S. Bertoli   +16 more
semanticscholar   +1 more source

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