Heterologous Expression of Either Human or Soya Bean Ferritins in Budding Yeast Reveals Common Functions Protecting Against Oxidative Agents and Counteracting Double-Strand Break Accumulation [PDF]
BiomoleculesFerritins are globular proteins that, upon self-assembly in nanocages, are capable of bio-safely storing huge concentrations of bioavailable iron. They are present in most cell types and organisms; one of the exceptions is yeast.
Nuria Pujol Carrión +1 more
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Ferritins: furnishing proteins with iron [PDF]
Journal of Biological Inorganic Chemistry, 2016 Ferritins are a superfamily of iron oxidation, storage and mineralization proteins found throughout the animal, plant, and microbial kingdoms. The majority of ferritins consist of 24 subunits that individually fold into 4-α-helix bundles and assemble in ...
Justin M Bradley +2 more
exaly +3 more sources
Diversity of Fe 2+ entry and oxidation in ferritins [PDF]
Current Opinion in Chemical Biology, 2017 The essential metal iron presents two major problems for life: it is potentially highly toxic due to its redox activity, and its extremely low solubility in aqueous solution in the presence of O2 can make it hard to acquire and store safely.
Justin M Bradley, Nick E Le Brun
exaly +3 more sources
A natural biogenic nanozyme for scavenging superoxide radicals [PDF]
Nature CommunicationsBiominerals, the inorganic minerals of organisms, are known mainly for their physical property-related functions in modern living organisms. Our recent discovery of the enzyme-like activities of nanomaterials, coined as nanozyme, inspires the hypothesis ...
Long Ma +9 more
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Iron reduction via periodic calibrated phlebotomy to target ferritin lowers cancer incidence and mortality in patients with peripheral artery disease: further insights from the FeAST trial [PDF]
Frontiers in OncologyPaul Pisarik
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Recombinant ferritins for multimodal nanomedicine
Journal of Enzyme Inhibition and Medicinal Chemistry, 2023 In all living organisms, ferritins are a group of proteins important for maintaining iron homeostasis. Increasing amount of studies has shown that recombinant ferritins can be widely used in multimodal nanomedicine, especially for anticancer treatment ...
Yihao Li +5 more
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Association between serum ferritin levels and colorectal cancer risk in Korea [PDF]
The Korean Journal of Internal Medicine, 2022 Background/Aims The concentration of serum ferritin, a storage form of iron, may be associated with carcinogenesis in various cancers. There are only limited studies on the relationship between serum ferritin levels and colorectal cancer (CRC) risk ...
Hyunho Kim +3 more
doaj +1 more source
Structural comparison of two ferritins from the marine invertebrate Phascolosoma esculenta
FEBS Open Bio, 2021 For marine invertebrates with no adaptive immune system, ferritin is a major intracellular iron‐storage protein with a critical role in innate immunity.
Tinghong Ming +10 more
doaj +1 more source
The Journal of Qazvin University of Medical Sciences, 2022 Background: This study aimed to compare the serum levels of C-reactive protein (CRP) and ferritin in the first trimester of pregnancy between normal and abnormal pregnant women (complicated with gestational diabetes) to determine if these chemicals have ...
Fatemeh Lalooha +4 more
doaj +1 more source
Clinical Profile and Cardiac Complications of Haemoglobinopathies in Children at Tertiary Care Centre in Hyderabad, India: A Cross-sectional Study [PDF]
Journal of Clinical and Diagnostic Research, 2022 Introduction: Haemoglobinopathies include a group of inherited, chronic haemolytic anaemias which are transfusion dependent. Haemolytic Anaemia is a public health problem and has a high prevalence in Asian countries.
Paramesh Pandala +4 more
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