Results 1 to 10 of about 194,437 (305)

Ferritin for the clinician [PDF]

Blood Reviews, 2009
Ferritin, a major iron storage protein, is essential to iron homeostasis and is involved in a wide range of physiologic and pathologic processes. In clinical medicine, ferritin is predominantly utilized as a serum marker of total body iron stores. In cases of iron deficiency and overload, serum ferritin serves a critical role in both diagnosis and ...
Lan G Coffman, Suzy V Torti, Frank M Torti   +2 more
exaly   +3 more sources

Mitochondrial Ferritin: Its Role in Physiological and Pathological Conditions

Cells, 2021
In 2001, a new type of human ferritin was identified by searching for homologous sequences to H-ferritin in the human genome. After the demonstration that this ferritin is located specifically in the mitochondrion, it was called mitochondrial ferritin ...
Sonia Levi, Maddalena Ripamonti, Marko Dardi, Anna Cozzi, Paolo Santambrogio   +4 more
doaj   +2 more sources

Threshold ferritin and hepcidin concentrations indicating early iron deficiency in young women based on upregulation of iron absorption

EClinicalMedicine, 2021
Background: Plasma ferritin is a widely used indicator to detect iron deficiency, but the threshold ferritin that defines iron deficiency remains uncertain.
Valeria Galetti, Nicole U. Stoffel, Chloé Sieber, Christophe Zeder, Diego Moretti, Michael B. Zimmermann   +5 more
doaj   +2 more sources

Association between serum ferritin and uric acid levels and nonalcoholic fatty liver disease in the Chinese population [PDF]

PeerJ, 2023
Background The prevalence of nonalcoholic fatty liver disease (NAFLD) is increasing worldwide. Accumulating evidence suggests that serum ferritin and uric acid (UA) are strongly associated with the risk of NAFLD, but no consensus has been reached ...
Fangli Zhou, Xiaoli He, Dan Liu, Yan Ye, Haoming Tian, Li Tian   +5 more
doaj   +2 more sources

Ferritin Is Secreted from Primary Cultured Astrocyte in Response to Iron Treatment via TRPML1-Mediated Exocytosis

Cells, 2023
Impaired iron homeostasis has been proven to be one of the critical contributors to the pathology of Parkinson’s disease (PD). Ferritin is considered an intracellular protein responsible for storing cytosolic iron. Recent studies have found that ferritin
Xiaoqi Yu, Zhixin Xiao, Junxia Xie, Huamin Xu   +3 more
doaj   +1 more source

Peran Ferritin pada Stroke Iskemik Akut

Jurnal Neuroanestesi Indonesia, 2021
Stroke merupakan defisit neurologis yang terjadi karena jejas fokal akut pada sistem saraf pusat yang semata-mata terjadi karena gangguan vaskuler, termasuk infark serebri maupun perdarahan.
Lisda Amalia
doaj   +1 more source

A Novel View of Ferritin in Cancer

Biochimica et biophysica acta. Reviews on cancer, 2023
Since its discovery more than 85 years ago, ferritin has principally been known as an iron storage protein. However, new roles, beyond iron storage, are being uncovered.
B. Shesh, J. Connor
semanticscholar   +1 more source

NCOA4 drives ferritin phase separation to facilitate macroferritinophagy and microferritinophagy

Journal of Cell Biology, 2022
Ohshima et al. demonstrate that the iron-storage protein ferritin undergoes liquid–liquid phase separation, which is mediated by multivalent interactions with NCOA4.
Tomoko Ohshima, Hayashi Yamamoto, Y. Sakamaki, C. Saito, N. Mizushima   +4 more
semanticscholar   +1 more source

Safety and immunogenicity of a ferritin nanoparticle H2 influenza vaccine in healthy adults: a phase 1 trial

Nature Medicine, 2022
Currently, licensed seasonal influenza vaccines display variable vaccine effectiveness, and there remains a need for novel vaccine platforms capable of inducing broader responses against viral protein domains conserved among influenza subtypes.
Katherine V. Houser, Grace L. Chen, Cristina A Carter, M. Crank, Thuy A. Nguyen, Maria C. Burgos Florez, N. Berkowitz, Floreliz H. Mendoza, Cynthia S. Hendel, Ingelise J. Gordon, Emily E. Coates, Sandra Vazquez, Judy A. Stein, Christopher L. Case, H. Lawlor, K. Carlton, M. Gaudinski, L. Strom, A. Hofstetter, C. Liang, S. Narpala, C. Hatcher, Rebecca A. Gillespie, A. Creanga, M. Kanekiyo, J. Raab, Sarah F. Andrews, Yi Zhang, E. Yang, Lingshu Wang, K. Leung, W. Kong, Alec W. Freyn, R. Nachbagauer, P. Palese, R. Bailer, A. McDermott, R. Koup, J. Gall, F. Arnold, J. Mascola, B. Graham, J. Ledgerwood, Joseph Lasonji Abidemi O. Pamela Jennifer Brenda Laura Ja Casazza Holman Ola Costner Cunningham Larkin Novik, J. Casazza, Lasonji Holman, Abidemi O. Ola, Pamela J. M. Costner, Jennifer Cunningham, B. Larkin, L. Novik, J. Saunders, W. Whalen, Xiaolin Wang, A. Eshun, Alison Taylor, K. Cheng, C. Laurencot, J. Cox, S. Sitar, L. Le, Iris Pittman, O. Vasilenko, R. S. Rothwell, G. Yamshchikov, Eugenia Burch, S. Hickman, Olga Trofymenko, Catina Boyd, Preeti Apte, C. T. Cartagena, Renunda Hicks, Pernell Williams, Zana Blaku, Colin Tran   +74 more
semanticscholar   +1 more source

H-Ferritin Is Preferentially Incorporated by Human Erythroid Cells through Transferrin Receptor 1 in a Threshold-Dependent Manner. [PDF]

PLoS ONE, 2015
Ferritin is an iron-storage protein composed of different ratios of 24 light (L) and heavy (H) subunits. The serum level of ferritin is a clinical marker of the body's iron level.
Soichiro Sakamoto, Hiroshi Kawabata, Taro Masuda, Tatsuki Uchiyama, Chisaki Mizumoto, Katsuyuki Ohmori, H Phillip Koeffler, Norimitsu Kadowaki, Akifumi Takaori-Kondo   +8 more
doaj   +1 more source