Results 31 to 40 of about 194,437 (305)
Ferritin in cancer therapy: A pleiotropic tumoraffin nanocage‐based transport
Cancer Medicine, 2023 Background Ferritin, a ubiquitously distributed iron storage protein, can specifically target tumor cells through transferrin receptor 1. Due to its rearrangeable nanocage structure, ferritin can be loaded with anticancer drugs.
Guodong Deng +13 more
doaj +1 more source
British Journal of Cancer, 2020 AbstractElevated levels of serum ferritin (SF) are observed in several types of cancer; however, little is known on the association between ferritin and glioma, the most frequent type of human primary brain tumour. Here we report that GBM patients show significantly increased pre-surgical SF levels (i.e. ferritinaemia) within the SF reference range and
Jaksch-Bogensperger, Heidi +9 more
openaire +2 more sources
bioRxiv, 2020 Development of a safe and effective SARS-CoV-2 vaccine is a public health priority. We designed subunit vaccine candidates using self-assembling ferritin nanoparticles displaying one of two multimerized SARS-CoV-2 spikes: full-length ectodomain (S-Fer ...
Abigail E. Powell +9 more
semanticscholar +1 more source
Ferritin-based nanomedicine for disease treatment
Medical Review, 2023 Ferritin is an endogenous protein which is self-assembled by 24 subunits into a highly uniform nanocage structure. Due to the drug-encapsulating ability in the hollow inner cavity and abundant modification sites on the outer surface, ferritin nanocage ...
Zhu Yuanjun +7 more
doaj +1 more source
Enhanced Cellular Uptake of H-Chain Human Ferritin Containing Gold Nanoparticles
Pharmaceutics, 2021 Gold nanoparticles (AuNP) capped with biocompatible layers have functional optical, chemical, and biological properties as theranostic agents in biomedicine.
Italo Moglia +5 more
doaj +1 more source
Prognostic Values of Serum Ferritin and D-Dimer Trajectory in Patients with COVID-19
Viruses, 2021 Cytokine storm syndrome in patients with COVID-19 is mediated by pro-inflammatory cytokines resulting in acute lung injury and multiorgan failure. Elevation in serum ferritin and D-dimer is observed in COVID-19 patients. To determine prognostic values of
F. Qeadan +5 more
semanticscholar +1 more source
Salt-Dependent Aggregation and Assembly of -Expressed Ferritin
Dose-Response, 2016 Ferritin, with the primary function of iron storage, is a nearly ubiquitous protein found in most living organisms. Our recent investigations suggest that ferritin can assemble nanoparticles.
Wei Sun +7 more
doaj +1 more source
Characterization Analysis of Human Anti-Ferritin Autoantibodies
Antibodies, 2014 Anti-ferritin autoantibodies are found in many animals. Human ferritin-binding proteins (FBPs) were partially purified from human serum by ion-exchange chromatography and immobilized metal affinity chromatography with Zn2+.
Shusaku Higashi +4 more
doaj +1 more source
The regulatory effect of blood group on ferritin levels in aging: a retrospective study [PDF]
PeerJBackground Ferritin plays a pivotal role in the ageing process. Previous studies have identified statistically significant differences in ferritin levels among various ABO blood groups.
Ni Xiaolin, Fenghong Yao, Mingkang Pan
doaj +2 more sources
Outcome Predictive Value of Serum Ferritin in ICU Patients with Long ICU Stay
Medicina, 2020 Background and Objectives: The simplified interpretation of serum ferritin levels, according to which low ferritin levels indicate iron deficiency and high levels indicate hemochromatosis is obsolete, as in the presence of inflammation serum ferritin ...
Daniel Rusu +8 more
doaj +1 more source