Results 41 to 50 of about 81,213 (316)

Iron Oxidation and Core Formation in Recombinant Heteropolymeric Human Ferritins

Biochemistry, 2017
In animals, the iron storage and detoxification protein, ferritin, is composed of two functionally and genetically distinct subunit types, H (heavy) and L (light), which co-assemble in various ratios with tissue specific distributions to form shell-like ...
M. Mehlenbacher, Maura Poli, P. Arosio, P. Santambrogio, S. Levi, N. Chasteen, Fadi Bou-Abdallah   +6 more
semanticscholar   +1 more source

Iron detoxification and storage in human cytosolic ferritins

Iron is essential for almost all life, by playing a key role in a range of processes, including respiration and DNA synthesis. Iron also presents organisms with two problems: ferric iron is highly insoluble and so has poor bioavailability and ferrous ...
Bugg, Zinnia Daisy Poppy Clover Primrose
core   +4 more sources

Anemia e ferropenia em gestantes: dissensos de resultados de um estudo transversal Anemia and iron deficiency in pregnant women: disagreements among the results of a cross-sectional study

Revista Brasileira de Saúde Materno Infantil, 2007
OBJETIVOS: descrever as freqüências de anemia e ferropenia em gestantes de baixo risco, de acordo com a ferritina sérica e diferentes pontos de corte da concentração de hemoglobina (Hb).
Cristiane Campello Bresani, Bresani Ariani Impieri de Souza, Malaquias Batista Filho, José Natal Figueiroa   +3 more
doaj   +1 more source

Pulmonary Haemosiderosis Secondary to Hereditary Haemochromatosis; a Case Report

Journal of Cancer and Allied Specialties, 2020
Introduction: Hereditary haemochromatosis (HH) is an autosomal recessive disease of increased intestinal absorption of iron, leading to accumulation in tissues which may progress to organ damage, most commonly in the liver.
Waqas Jehangir, Alexander Karabachev, Elvira Umyarova   +2 more
doaj   +1 more source

Effect of high intensity interval training and use of Echium amoenum on serum ferritin and CRP levels in overweight and obese women [PDF]

Majallah-i Zanān, Māmā̓ī va Nāzā̓ī-i Īrān, 2020
Introduction: During obesity, inflammatory markers such as ferritin and C-reactive protein are increased, which is a major mechanism of atherosclerosis and insulin resistance.
Maryam Nasri, Farzaneh Taghian
doaj   +1 more source

Bacterioferritins and ferritins are distantly related in evolution - conservation of ferroxidase-center residues [PDF]

, 1991
Iron-storage proteins can be divided into two classes; the bacterioferritins and ferritins. In spite of many apparent structural and functional analogies, no significant amino acid sequence similarity has been detected previously. This report now reveals
Yewdall SJ, Harrison PM, Smith, J.M.A., J.R. Guest, J.M.A. Smith, Andrews SC, Yewdall, S.J., Harrison, P.M., S.C. Andrews, Smith JMA, Andrews, S.C., P.M. Harrison, S.J. Yewdall, Guest, J.R., Guest JR   +14 more
core   +1 more source

Structural characterization of encapsulated ferritin provides insight into iron storage in bacterial nanocompartments

eLife, 2016
Ferritins are ubiquitous proteins that oxidise and store iron within a protein shell to protect cells from oxidative damage. We have characterized the structure and function of a new member of the ferritin superfamily that is sequestered within an ...
Didi He, Sam Hughes, Sally Vanden-Hehir, Atanas Georgiev, Kirsten Altenbach, Emma Tarrant, C Logan Mackay, Kevin J Waldron, David J Clarke, Jon Marles-Wright   +9 more
doaj   +1 more source

Conservation of the structural and functional architecture of encapsulated ferritins in bacteria and archaea

bioRxiv, 2018
Iron is an essential element for many biological processes; however, due to its high reactivity iron can also be very toxic, producing reactive oxygen species through Fenton chemistry.
D. He, Cecilia Piergentili, J. Ross, E. Tarrant, L. Tuck, C. Mackay, Zak McIver, Kevin J. Waldron, David J. Clarke, J. Marles-Wright   +9 more
semanticscholar   +1 more source

Recombinant H-chain ferritins: Effects of changes in the 3-fold channels [PDF]

, 1989
Human H-chain ferritins bearing sequence changes in the 3-fold channels have been expressed in E. coli to investigate the role of these channels in iron-storage processes. The proteins assemble into shells resembling those of native ferritins.
Alessandra Luzzago, Harrison, Pauline M., Amyra Treffry, Luzzago, Alessandra, Pauline M. Harrison, Gianni Cesareni, Treffry, Amyra, Cesareni, Gianni   +7 more
core   +1 more source

Sudden anaerobization in Amphibacillus xylanus increases intracellular labile ferrous iron and inhibits cell growth

FEBS Open Bio, EarlyView.
Abruptly changing from aerobic to anaerobic conditions (sudden anaerobization) induced growth inhibition and a significant increase in intracellular labile ferrous iron in the aerotolerant anaerobe Amphibacillus xylanus. We found that free flavins mediate efficient electron transfer from NADH to ferric iron under anaerobic conditions, suggesting that ...
Shinya Kimata, Yoichi Sakai, Keisuke Tanaka, Etsuro Yoshimura, Ken Kitano, Morio Ishikawa, Tadahiro Nakamoto, Tsutomu Takayama, Hirofumi Inoue, Kaho Nomura, Tomonori Suzuki, Masataka Uchino, Akira Abe, Youichi Niimura   +13 more
wiley   +1 more source