Results 191 to 200 of about 81,213 (316)

Baicalin Induces Ferroptosis in Breast Cancer Through a Novel STAT3/HO‐1/GPX4 Regulatory Axis

open access: yesPhytotherapy Research, EarlyView.
BA inhibits STAT3 phosphorylation and activation in BC cells, accompanied by decreased expression of HO‐1 and GPX4. Reduced GPX4 activity impairs lipid peroxide clearance, promoting ROS accumulation and lipid peroxidation, which ultimately triggers ferroptosis and inhibits cell proliferation.
Tingting Guo   +11 more
wiley   +1 more source

Neohesperidin Alleviates Ferroptosis in Doxorubicin‐Induced Cardiotoxicity via Mettl3‐m6A‐Nrf2 Signaling

open access: yesPhytotherapy Research, EarlyView.
Neohesperidin alleviates doxorubicin‐induced cardiotoxicity by inhibiting METTL3‐mediated m6A modification of Nrf2 mRNA, thereby regulating Nrf2 and suppressing ferroptosis. ABSTRACT Doxorubicin (DOX) has antitumor efficacy, but its clinical application is restricted by multiple side effects, especially cardiotoxicity.
Ruijia Wen   +9 more
wiley   +1 more source

Type I interferon overactivation in sera of patients with anti‐MDA5‐positive dermatomyositis‐associated interstitial lung disease

open access: yesRheumatology &Autoimmunity, EarlyView.
Sera from patients with anti‐MDA5‐positive dermatomyositis‐associated interstitial lung disease (ILD) exhibit significantly higher type I interferon (IFN‐I) bioactivity and interferon‐stimulated gene‐inducing activity compared to anti‐ARS‐positive ILD and healthy controls.
Shohei Nakamura   +3 more
wiley   +1 more source

Case series: Kikuchi‐Fujimoto disease with diagnostic overlap

open access: yesRheumatology &Autoimmunity, EarlyView.
Kikuchi‐Fujimoto disease (KFD) is a rare, self‐limiting necrotizing lymphadenitis that poses significant diagnostic challenges due to its overlap with tuberculosis, systemic lupus erythematosus (SLE), and malignancy. We present four cases highlighting distinct diagnostic complexities: KFD mimicking tuberculosis with concomitant latent TB infection and ...
Ecem Kalemoglu   +6 more
wiley   +1 more source

Discriminating Between Living and Dead Bacteria With a Field‐Effect Transistor Based on Nano‐Channels

open access: yesSmall, EarlyView.
Bacterial viability is determined in a complex environment with a field‐effect biological transistor with a limit of detection of a single bacterium. Living, antibiotic‐treated, thermally denatured, and inhibited E. coli generate distinct electrical signatures, enabling label‐free single‐cell detection and providing new opportunities for rapid ...
Bar Chen   +17 more
wiley   +1 more source

FERRITIN

open access: yesJournal of Biological Chemistry, 1943
P.F. Hahn   +3 more
openaire   +2 more sources

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