Results 191 to 200 of about 7,994 (300)

The role of iron in normal and impaired testicular function

open access: yesAndrology, EarlyView.
Abstract Iron plays a critical role in testicular physiology, impacting spermatogenesis, testosterone production, and overall testicular function. Iron homeostasis is maintained through systemic and cellular regulatory mechanisms, including hepcidin‐mediated systemic iron control and the iron‐responsive element/iron regulatory protein (IRE/IRP) system ...
Aileen Harrer   +2 more
wiley   +1 more source

Developmental Trends in Serum Iron, Transferrin, and Transferrin Saturation From Birth to 12 Months

open access: yesActa Paediatrica, EarlyView.
ABSTRACT Aim There is a need for updated reference intervals for iron status biomarkers during infancy. This study aimed to investigate reference interval trends and diurnal variation of iron, transferrin, and transferrin saturation in infants subjected to delayed cord clamping at birth (DCC). Methods Data analysis from population‐based Swedish studies,
Sara Marie Larsson   +5 more
wiley   +1 more source

Ferritin iron uptake and oxidation are dynamically modulated by nucleotide phosphate architecture via electrostatic gating. [PDF]

open access: yesInt J Biol Macromol
Rajendran A   +6 more
europepmc   +1 more source

Clinical features and prognostic factors of adult systemic chronic active EBV disease: A retrospective analysis in Japan

open access: yesBritish Journal of Haematology, EarlyView.
ALT and ferritin were adverse prognostic markers enabling risk stratification in adult systemic chronic active Epstein–Barr virus disease (sCAEBV). In hydroa vacciniforme lymphoproliferative disorder (HV‐LPD), Epstein–Barr virus (EBV) infection of CD4+ cells was associated with progression to sCAEBV.
Aika Fuseya   +15 more
wiley   +1 more source

Correlative imaging reveals metal dyshomeostasis and altered zinc coordination environments in a pre-clinical Type 2 diabetes model. [PDF]

open access: yesMetallomics
Ellison G   +8 more
europepmc   +1 more source

Neutrophil extracellular traps induced by activated platelets as a cause of neutrophil–platelet aggregation in β‐thalassaemia/haemoglobin E patients

open access: yesBritish Journal of Haematology, EarlyView.
Abnormal neutrophils and platelets in splenectomised β‐thalassaemia/haemoglobin E (HbE) disease contribute to neutrophil–platelet aggregation, leading to a high risk of thrombus formation. Activated platelets induce neutrophils to generate neutrophil extracellular trap (NETs) via the P‐selectin–P‐selectin glycoprotein ligand‐1 (PSGL1) pathway, which ...
Rattanawan Thubthed   +11 more
wiley   +1 more source

Hydroxyurea (hydroxycarbamide) use in adults with haemoglobin SC disease: A real‐world study in Quebec

open access: yesBritish Journal of Haematology, EarlyView.
Summary Haemoglobin SC (HbSC) disease is the second most prevalent form of sickle cell disease, but evidence for hydroxyurea (hydroxycarbamide; HU) to prevent pain episodes was limited until the prospective identification of variables as outcomes for treatment (PIVOT) trial.
Alice Girard   +10 more
wiley   +1 more source

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