Results 41 to 50 of about 10,617 (280)

Successful treatment of hemophagocytic lymphohistiocytosis in a trauma patient: a case report [PDF]

Journal of Trauma and Injury
Hemophagocytic lymphohistiocytosis (HLH) is a rare, life-threatening hyperinflammatory syndrome characterized by excessive activation of the immune system.
Young Soo Chung, Jihoon Kim
doaj   +1 more source

New insights into the role of heme oxygenase-1 in acute kidney injury

Kidney Research and Clinical Practice, 2020
Acute kidney injury (AKI) is attended by injury-related biomarkers appearing in the urine and serum, decreased urine output, and impaired glomerular filtration rate.
Meryl Nath, Anupam Agarwal
doaj   +1 more source

A Cytosolic Iron Chaperone that Delivers Iron to Ferritin [PDF]

, 2008
Ferritins are the main iron storage proteins found in animals, plants and bacteria. The capacity to store iron in ferritin is essential for life in mammals, but the mechanism by which cytosolic iron is delivered to ferritin is unknown.
Bencze, Krisztina Z., Philpott, Caroline C., Shi, Haifeng, Stemmler, Timothy L.   +3 more
core   +2 more sources

Tyr25, Tyr58 and Trp133 of Escherichia coli bacterioferritin transfer electrons between iron in the central cavity and the ferroxidase centre [PDF]

, 2017
Ferritins are 24meric proteins that overcome problems of toxicity, insolubility and poor bioavailability of iron in all types of cells by storing it in the form of a ferric mineral within their central cavities.
Abdul-Tehrani, Andrews, Andrews, Baaghil, Bauminger, Bou-Abdallah, Bradley, Bradley, Bradley, Bradley, Chaplin, Cheesman, Crow, Dimitri A. Svistunenko, Eshelman, Geoffrey R. Moore, Harrison, Hingorani, Hudson, Ito, Justin M. Bradley, Kwak, Laufberger, Lawson, Le Brun, Le Brun, Le Brun, Minnihan, Nick E. Le Brun, Pagba, Rajagopal, Reeder, Stiefel, Svistunenko, Theil, Thompson, Turano, Umena, Weeratunga, Weeratunga, Wong, Yang, Yasmin   +42 more
core   +2 more sources

Adjunctive Therapeutic Plasma Exchange in Refractory Adult‐Onset Still's Disease Complicated by Secondary Macrophage Activation Syndrome: A Single‐Center Experience

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Adult‐onset Still's disease (AOSD) complicated by macrophage activation syndrome (MAS) carries substantial mortality. The role of therapeutic plasma exchange (TPE) remains uncertain. Methods We retrospectively analyzed patients with AOSD‐MAS treated with TPE at a single‐center.
Masataka Ueda, Tomohiro Saito, Masahide Mizobuchi, Tomoki Shimomura, Saki Kawamori, Mitsuru Kawanishi, Natsuko Hattori, Jo Sugiyama, Satoshi Tsubata, Hanami Horiguchi, Kazuki Abe, Nao Iida, Yuki Kajio, Nao Oguro, Ryo Yanai, Hirokazu Honda   +15 more
wiley   +1 more source

Valores de ferritina sérica em beta talassemia heterozigota Serum ferritin levels in beta thalassemia carrier

Revista Brasileira de Hematologia e Hemoterapia, 2010
A low iron level, the commonest nutritional deficiency in the world, is a public health problem in developing countries. On the other hand, an excessive amount of iron is toxic, causing several organic dysfunctions, such as diabetes, cirrhosis ...
Isabeth F. Estevão, Maria Cristina S. Souza, Antonio J. Manzato, Claudia R. Bonini-Domingos   +3 more
doaj   +1 more source

Improving Blueberry Anthocyanins’ Stability Using a Ferritin Nanocarrier

Molecules, 2023
Blueberries are fruits known for their high level of anthocyanins, which have high nutritional value and several biological properties. However, the chemical instability of anthocyanins is one of the major limitations of their application.
Wuyang Huang, Xingyu Zhao, Zhi Chai, Daniela D. Herrera-Balandrano, Bin Li, Yiyun Yang, Shan Lu, Zhigang Tu   +7 more
doaj   +1 more source

Isolation and partial characterization of two porcine spleen ferritin fractions with different electrophoretic mobility [PDF]

, 1996
Ferritin isolated from porcine spleen could routinely be separated in two fractions on nondenaturating gradient gels. Both fractions could be isolated with a purity of 96% when applied to two serially linked columns, each 200 cm in length, packed ...
Cleton-Soeteman, M.I. (Maud), Eijk, H.G. (Henk) van, Huijskes-Heins, M.I.E. (M. I E), Klepper, D. (D.), Noort, W.L. (W.) van, Van Gelder, C.M. (Carin)   +5 more
core   +1 more source

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source