Results 161 to 170 of about 119,944 (359)
In the context of chronic hyperglycemia, a DDR is initiated, leading to the pathological activation of DNA‐PKcs in the diabetic heart. This activated DNA‐PKcs directly interacts with and phosphorylates YAP1 at Thr226, thereby increasing the nuclear expression of YAP1.
Junyan Wang+10 more
wiley +1 more source
Does tree density or fertilisation in silvopastoral systems affect tree or pasture production ? [PDF]
N/
Mosquera-Losada, M.R.
core
Fertilisation of Flowers.—The Cuckoo [PDF]
As a fact interesting in connection with the fertilisation of flowers, I have observed that in Scabiosa arvensis the stamens are elongated and the anthers ripened successively—not simultaneously—in each individual floret, the first having fallen off the filament, while the fourth is yet colourless and curled up in the tube of the corolla, the other two
openaire +2 more sources
ACLY is vital for early embryo development. IGF‐1 activates AKT to phosphorylate ACLY, driving its nuclear localization and recruitment of HATs (P300/HAT1), boosting acetyl‐CoA production and histone acetylation for transcriptional activation. Conversely, ACLY deficiency (via knockdown, knockout, or AKT inhibition) reduces nuclear acetyl‐CoA, disrupts ...
Yerong Ma+18 more
wiley +1 more source
Towards a breakthrough in nutrient recycling : State-of-the-art and recommendations for developing policy instruments in Finland [PDF]
The report has been complemented on 11.9.2018This report describes the state-of-the-art in phosphorus and nitrogen recycling in Finland and looks at basic data on the volumes and geographical distribution of biomasses and their nutrients.
Grönroos, Juha+18 more
core
Eleven years’ data of grassland management data in Germany [PDF]
Juliane Vogt+29 more
doaj +3 more sources
This study integrates dual‐reporter genetics, imaging flow cytometry, and single‐cell sequencing to characterize rare bihormonal cells in mouse and human pancreatic islets. Gcg⁺Ins⁺ cells resemble α‐cells rather than transitional states. Cross‐species gene network analysis refines islet cell taxonomy and reveals human‐specific δ‐cell subtypes ...
Xin‐Xin Yu+10 more
wiley +1 more source
Inhibition of Ferroptosis Delays Aging and Extends Healthspan Across Multiple Species
This study identifies ferroptosis as a key driver of cellular senescence, with its inhibition delaying aging and extending healthspan across species. During senescence, ferroptosis worsens, increasing oxidative stress and lipid peroxidation, which accelerate aging.
Hai‐Jun Fu+15 more
wiley +1 more source