Results 191 to 200 of about 179,953 (391)
Temporal Transcriptional Regulation of Human Neuronal Differentiation via Forward Programming
Single‐cell profiling of TF‐induced forward programming versus stepwise dual‐SMAD differentiation reveals that divergent trajectories set the pace of neurogenesis. OLIG TFs advance cell‐cycle exit via NOTCH modulation, while NEUROD2 later accelerates maturation. The study elucidates transcriptional mechanisms governing differentiation timing, providing
Lingling Zhu +13 more
wiley +1 more source
Thirty Years of the Biology of Spermatozoa: The Rise and Future of an Evolutionary Paradigm. [PDF]
Simmons LW.
europepmc +1 more source
Glutamine deprivation triggers ACSL5 upregulation in tumor cells, sustaining their viability via dual metabolic rewiring programs. ACSL5 enhances glycolysis by relieving p53's inhibition of PGAM1 while also sustaining mitochondrial respiration and TCA cycle flux through promoting IDH2 dimerization.
Shuai Tian +11 more
wiley +1 more source
Impact of Fertilisation on the Bacterial Core Microbiome of Grassland Soils: Abundance in the Field and Growth In Vitro. [PDF]
Chamedjeu RR +7 more
europepmc +1 more source
The influence of microbiological fertilisers on the productivity and quality of winter wheat [PDF]
Yuri Koryagin +3 more
openalex +1 more source
We present a dual‐organ, biomarker‐integrated ovaryendometrium organ‐on‐a‐chip that recapitulates 3D tissue complexity, menstrual cycle dynamics, and hormonal crosstalk. This platform enables real‐time, cell‐typespecific fluorescent readouts of reproductive toxicity using ANGPTL4 and SERPINB2 as early‐response reporters.
Soo‐Rim Kim +6 more
wiley +1 more source
Selenium (IV) and Sulphur (VI) as Elements Modifying Plant Quality: Content of Selenium and Sulphur Forms in Wheat. [PDF]
Brodowska MS +2 more
europepmc +1 more source

