Results 131 to 140 of about 1,482,535 (355)

Viral Systemic Movement Is Enhanced by Alteration of a Structural Phloem Protein by the Insect Vector

open access: yesAdvanced Science, EarlyView.
Aphids release salivary protein GLD into plants, which induces ROS in the phloem. This leads to the intermolecular disulfide bonds formation among SEO proteins, promoting their transition from the dispersed state to the aggregated state. SEO can interact with CMV CP.
Huijuan Guo   +7 more
wiley   +1 more source

Equivalent outcomes of human oocytes after vitrification or slow freezing with a modified rehydration protocol

open access: yesReproductive Biology and Endocrinology
Background According to data from numerous research studies and reviews, the efficiency of the oocyte slow-freezing method is believed to be compromised.
Krzysztof Papis   +5 more
doaj   +1 more source

Nociceptive Nerve‐Derived CGRP Exacerbates Uterine Fibrogenesis in Adenomyosis by Promoting CD140b+ CD146+ Fibroblast Differentiation

open access: yesAdvanced Science, EarlyView.
This study investigates adenomyosis fibrosis in relation to nociceptive nerves. Nociceptive nerve‐secreted CGRP promotes RAMP1hi CD140b+ CD146+ fibroblast differentiation into myofibroblasts through ERK activation, causing severe fibrosis. Rimegepant‐induced CGRP/RAMP1 signaling blockade alleviates fibrosis and restores fertility in a mouse model. This
Zi Ye   +11 more
wiley   +1 more source

Patterns of lowest-low fertility in Europe [PDF]

open access: yes
In this paper we conduct descriptive aggregate analyses to revisit the relation between low and lowest-low period fertility on the one, and cohort fertility and key fertility-related behaviors---such as leaving the parental home, marriage and female ...
Francesco C. Billari, Hans-Peter Kohler
core  

High‐Resolution Genomic Resources for Trait Mapping and Precision Breeding for Adzuki Bean (Vigna angularis)

open access: yesAdvanced Science, EarlyView.
This study establishes crucial genomic resources for adzuki bean, including a reference genome, variation map, and the AdzukiBeanAtlas toolkit. We identify key candidate genes (ANKRD50, NAC73, ANR1, NPF5.4) for important agronomic traits through Genome‐Wide Association Studies (GWAS).
Liangliang Hu   +26 more
wiley   +1 more source

Hepatic KLF9 Deficiency Inhibits Dehydroepiandrosterone (DHEA)‐Induced Polycystic Ovary Syndrome via Liver‐Ovary Axis

open access: yesAdvanced Science, EarlyView.
The study shows that liver is a previously unrecognized extraovarian organ that plays a key role about androgen homeostasis in the development of DHEA‐induced PCOS. DHEA is the most common precursor of active androgen, such as DHT, and KLF9 is required for the conversion of DHEA to DHT and hepatic KLF9 might be a potential therapeutic target for PCOS ...
Jianli Song   +11 more
wiley   +1 more source

Malthus to Modernity: England’s First Fertility Transition, 1760-1800 [PDF]

open access: yes
English fertility history is generally regarded as having been composed of two re-gimes: an era of unregulated marital fertility, from at least 1540 to 1890, then the modern era, with regulated marital fertility, lower for higher social classes.
Clark, Gregory, Cummins, Neil
core   +1 more source

Auditory Hair Cell Mechanotransduction Channels Dynamically Shape the Mechanical Properties of Their Membrane Environment

open access: yesAdvanced Science, EarlyView.
This work shows, for the first time, that the stereocilia membrane in cochlear hair cells is dynamically regulated by the mechanotransduction channel to impact the membrane mechanical properties. This work provides direct evidence that the opening and closing associated with the MET channel is regulating the membrane viscosity suggesting that the MET ...
Shefin Sam George, Anthony J. Ricci
wiley   +1 more source

Fertility of Turkish and Moroccan women in the Netherlands: Adjustment to native level within one generation [PDF]

open access: yes
The annual figures on the fertility of Turkish and Moroccan women show that the sharp decline that took place up to the mid nineties was reduced or stagnated.
Han Nicolaas, Joop Garssen
core  

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