Results 21 to 30 of about 295,957 (265)

Fertilization 2: Polyspermic Fertilization [PDF]

, 2017
During fertilization in animals, a haploid egg nucleus fuses with a haploid sperm nucleus to restore the diploid genome. In most animals including mammals, echinoderms, and teleostei, the penetration of only one sperm into an egg is ensured at fertilization because the entry of two or more sperm is prevented by polyspermy block systems in these eggs ...
openaire   +3 more sources

Why and When Are Evidence‐Based Interventions Adopted in Paediatric Supportive Care? A Qualitative Exploration of the Determinants of Photobiomodulation Implementation

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Oral mucositis is a common and debilitating side effect of childhood cancer and stem cell transplant treatments. It affects the quality of life of children and young people (CYP) and places a strain on services. Photobiomodulation is recommended for oral mucositis prevention in international guidance but is poorly implemented in UK ...
Claudia Heggie, Kara A. Gray‐Burrows, Peter F. Day, Bob Phillips, Carl A. Thompson   +4 more
wiley   +1 more source

Investigation into Platelet Rich Plasma (PRP) Infusions Within the Intrauterine Cavity, to Support the Development of Endometrial Lining in Transfer Cycle Patients

Fertility & Reproduction, 2022
Background: Poor endometrial lining is classically referenced as
Jenyne ALCOCK, Dr Lynn BURMEISTER, Shelley ZHANG, Eve GLAGE, Kelli SORBY   +4 more
doaj   +1 more source

Insights into a long life without cancer: The case of the bowhead whale

Molecular Oncology, EarlyView.
Long‐lived, large‐bodied organisms have evolved powerful anticancer mechanisms that preserve cellular and tissue integrity across extended lifespans. A recent study by Firsanov et al. shows that greater genome stability is a key factor underlying the remarkable longevity and cancer resistance of one such species, the bowhead whale.
Inés Paniagua, Johanna A. Joyce
wiley   +1 more source

The Complexity Around Mosaic Embryo Decision Making– A Genetic Counselling Perspective

Fertility & Reproduction, 2022
Background: In recent years there is an evident increase in the interest of transferring mosaic embryos. Our genetic counselling team have reported mosaic results to over 250 patients since the beginning of 2020, and there is an upward trend in patient ...
Maddie TEED, Abbie JEDWAB, Chloe STUTTERD, Kelli SORBY, Alice WEEKS   +4 more
doaj   +1 more source

DNA methylation and expression of MAPRE3 affect overall survival of early‐stage non‐small cell lung cancer patients

Molecular Oncology, EarlyView.
Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen, Jiancheng Cheng, Ruili Hou, Xiaoyuan Zheng, Li Su, Maria Moksnes Bjaanæs, Anna Karlsson, Maria Planck, Johan Staaf, Åslaug Helland, Manel Esteller, David C. Christiani, Feng Chen, Xiaofei Cao, Ruyang Zhang   +14 more
wiley   +1 more source

Embryo utilisation rate and transferable embryo to oocyte ratio correlate positively with livebirth rate but negatively with oocyte number: analysis of 14,156 fresh IVF/ICSI cycles

Journal of Ovarian Research
Background The live birth rates (LBRs) do not rise after a certain number of oocytes are collected in fresh IVF cycles. Although the detrimental effect of high ovarian response on the endometrium has been recognised, the effect of high oocyte yield on ...
Adrija Kumar Datta, Geeta Nargund, Martin Wilding, Sam Dobson, Stuart Campbell   +4 more
doaj   +1 more source

Overview of molecular signatures of senescence and associated resources: pros and cons

FEBS Open Bio, EarlyView.
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas, Sylvia Vagena, Pavlos Pantelis, Giorgos Theocharous, Russel Petty, Konstantinos Evangelou, Vassilis G. Gorgoulis   +6 more
wiley   +1 more source

Understanding the impact of lifestyle and demographic factors on DNA fragmentation index (DFI) among infertile men

BMC Urology
Background Sperm DNA fragmentation detection methods include SCSA, SCD, COMET assay, and TUNEL. In 2021, the DFI test became the first evidence-based sperm DNA integrity test included in international guidelines. However, limited data exists from Nigeria.
Abayomi Bolaji Ajayi, Victor Ajayi, Kazeem Adewale Osuolale, Ngozi Obi, Roselyn Obasa-Gbadebo, Toluwanimi Balogun, Anuoluwa Alaka, Olaoluwa Musa, Edith Omokhegbele   +8 more
doaj   +1 more source

#63 : Clinical Prognosis of Human Blastocysts Showing Spontaneous Collapsing: A Systematic Review and Meta-Analysis

Fertility & Reproduction, 2023
Background and Aims: Spontaneous collapsing (SC) is a relatively new viability biomarker of human blastocysts which is only detectable via time-lapse videography.
Kate Bickendorf, Fang Qi, Kelli Peirce, Jay Natalwala, Vincent Chapple, Yanhe Liu   +5 more
doaj   +1 more source