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Life, 2023 Fertility counseling should be offered to all individuals of young reproductive age early in the patient’s trajectory following a cancer diagnosis. Systemic cancer treatment and radiotherapy often have an inherent gonadotoxic effect with the potential to
Kenny A. Rodriguez-Wallberg +3 more
doaj +2 more sources
memo - Magazine of European Medical Oncology, 2020 Most of men with non-mosaic Klinefelter syndrome (KS) are azoospermic and for many decades use of donor semen was the only possible way of becoming a father for KS men. In the last 20 years, hundreds of non-mosaic azoospermic KS men have been submitted to testicular sperm extraction (TESE) and an overall sperm retrieval rate (SRR) of approximately
Barbonetti A. +5 more
+10 more sources
Ugeskrift for laeger, 2021 Fertility preservation should be considered in girls and young women faced with a potentially gonadotoxic treatment such as chemotherapy. IVF can be performed with the aim to collect and freeze the oocytes, or ovarian tissue can be cryopreserved and transplanted back to the patient at a later stage.
Colmorn, Lotte Berdiin +3 more
+10 more sources
Clinical Endocrinology, 2012 Advances in early diagnosis and cancer treatment have allowed the quality of life postcancer treatment as a recognized issue, and efforts have been made to preserve the fertility potential. Radiotherapy and chemotherapy have detrimental effects on ovarian reserve. Well-established methods against radiotherapy-induced gonadotoxicity are pelvic shielding
Pascale Jadoul +2 more
+6 more sources
Mayo Clinic Proceedings, 2011 Of the estimated 1.5 million men and women who were diagnosed as having cancer in 2010, approximately 10% are younger than 45 years. For these individuals, cancer treatment can be lifesaving but can permanently affect reproductive capacity. The American Society of Clinical Oncology has recommended that oncologists discuss the possibility of infertility
Pasquale Patrizio, A. L. Caplan
openaire +3 more sources
Human Sperm Morphology as a Marker of Its Nuclear Quality and Epigenetic Pattern
Cells, 2022 Background: Human sperm chromatin condensation is a sum of epigenetic events that allows for the near-complete replacement of histones with protamines.
Marion Bendayan +6 more
doaj +1 more source
Reproductive Biology and Endocrinology, 2022 Background In absence of contraindication, breast cancer patients of reproductive age can undergo fertility preservation with controlled ovarian stimulation for oocyte/embryo cryopreservation before the administration of potentially gonadotoxic ...
Imane Lalami +8 more
doaj +1 more source
Fertility preservation in pediatric healthcare: a review
Frontiers in Endocrinology, 2023 Survival rates for children and adolescents diagnosed with malignancy have been steadily increasing due to advances in oncology treatments. These treatments can have a toxic effect on the gonads.
Lin Chen, Z. Dong, Xiaoyan Chen
semanticscholar +1 more source
Fertility Preservation in Women with Endometriosis
Journal of Clinical Medicine, 2023 Several mechanisms have been implicated in the pathogenesis of endometriosis-related infertility. For patients considering surgery, the risk of iatrogenic injury is among the most important factors in the context of fertility preservation, along with age
Sabrina Rangi +3 more
semanticscholar +1 more source
BRCA Mutations and Fertility Preservation
International Journal of Molecular Sciences, 2023 Hereditary cancers mostly affect the adolescent and young adult population (AYA) at reproductive age. Mutations in BReast CAncer (BRCA) genes are responsible for the majority of cases of hereditary breast and ovarian cancer.
J. Dias Nunes, I. Demeestere, M. Devos
semanticscholar +1 more source