Results 1 to 10 of about 31,457 (267)

Uterine fixation: advancing a multidisciplinary strategy for fertility preservation. [PDF]

F S Rep
Yazdani A, Christianson MS.
europepmc   +2 more sources

Human Sperm Morphology as a Marker of Its Nuclear Quality and Epigenetic Pattern

Cells, 2022
Background: Human sperm chromatin condensation is a sum of epigenetic events that allows for the near-complete replacement of histones with protamines.
Marion Bendayan, Liliana Caceres, Emine Saïs, Nelly Swierkowski-Blanchard, Laura Alter, Amélie Bonnet-Garnier, Florence Boitrelle   +6 more
doaj   +1 more source

The Late Effects of Cancer Treatment on Female Fertility and the Current Status of Fertility Preservation—A Narrative Review

Life, 2023
Fertility counseling should be offered to all individuals of young reproductive age early in the patient’s trajectory following a cancer diagnosis. Systemic cancer treatment and radiotherapy often have an inherent gonadotoxic effect with the potential to
Kenny A. Rodriguez-Wallberg, Yanyu Jiang, Tobias Lekberg, Hanna P. Nilsson   +3 more
doaj   +1 more source

Is letrozole during ovarian stimulation useful in breast cancer patients undergoing fertility preservation to reduce early luteal progesterone levels following GnRH-agonist trigger?

Reproductive Biology and Endocrinology, 2022
Background In absence of contraindication, breast cancer patients of reproductive age can undergo fertility preservation with controlled ovarian stimulation for oocyte/embryo cryopreservation before the administration of potentially gonadotoxic ...
Imane Lalami, Julie Labrosse, Isabelle Cedrin-Durnerin, Marjorie Comtet, Claire Vinolas, Fabien Krief, Christophe Sifer, Maeliss Peigne, Michael Grynberg   +8 more
doaj   +1 more source

Human umbilical cord-derived mesenchymal stem cells (hUC-MSCs) alleviate excessive autophagy of ovarian granular cells through VEGFA/PI3K/AKT/mTOR pathway in premature ovarian failure rat model

Journal of Ovarian Research, 2023
Background Premature ovarian failure (POF) is one of the leading causes of female infertility and is accompanied by abnormal endocrine, seriously affecting female quality of life.
Wenjie Dai, Hong Yang, Bo Xu, Tiantian He, Ling Liu, Xiaoqian Ma, Jiaxue Ma, Guoqin Yang, Rui Si, Xiuying Pei, Xing Du, Xufeng Fu   +11 more
doaj   +1 more source

Metformin improves polycystic ovary syndrome in mice by inhibiting ovarian ferroptosis

Frontiers in Endocrinology, 2023
Background and objectivePCOS is a common metabolic disorder in women of reproductive age, which pathogenesis is very complex. The role of ferroptosis in PCOS is a novel finding, and the mechanistic studies are not clear. Metformin is a commonly used drug
Qingjie Peng, Xiaojiang Chen, Xiaoxia Liang, Jiahui Ouyang, Qiangqiang Wang, Shuai Ren, Haibo Xie, Chunhong Wang, Yaqun Sun, Xin Wu, Hetao Liu, Changchun Hei, Miao Sun, Qing Chang, Xinrui Liu, Guangyong Li, Guangyong Li, Rui He   +17 more
doaj   +1 more source

High-Survival Rate After Microinjection of Mouse Oocytes and Early Embryos With mRNA by Combining a Tip Pipette and Piezoelectric-Assisted Micromanipulator

Frontiers in Cell and Developmental Biology, 2021
Utilizing microinjection to introduce biological molecules such as DNA, mRNA, siRNA, and proteins into the cell is well established to study oocyte maturation and early embryo development in vitro. However, microinjection is an empirical technology.
Lei-Ning Chen, Lei-Ning Chen, Xiao-Yan Fan, Xiao-Yan Fan, Yi-Tong Liu, Shao-Qing Chen, Feng-Yun Xie, Feng-Yun Xie, Li Zeng, Juan Wen, Jin Li, Jun-Yu Ma, Jun-Yu Ma, Xiang-Hong Ou, Xiang-Hong Ou, Shi-Ming Luo, Shi-Ming Luo, Lei Guo, Lei Guo   +18 more
doaj   +1 more source

For patients with non-obstructive azoospermia, the outcome of testicular sperm extraction correlates with self-esteem, sexual health and the quality of the couple’s relationship

Basic and Clinical Andrology, 2022
Resume Introduction Quelques études concernant l’azoospermie ou les résultats négatifs de l’extraction de sperme testiculaire (TESE) montrent que ces résultats peuvent être liés à la dépression ou aux dysfonctions érectiles.
Marion BENDAYAN, Emine SAIS, Laura ALTER, Khadija FATHALLAH, Monique JAOUL, Pierre Olivier BOSSET, Geoffroy ROBIN, Florence BOITRELLE   +7 more
doaj   +1 more source

SIRT 3 was involved in Lycium barbarum seed oil protection testis from oxidative stress: in vitro and in vivo analyses

Pharmaceutical Biology, 2021
Context Lycium barbarum L. (Solanaceae) seed oil (LBSO) exerts LBSO exerts protective effects in the testis in vivo and in vitro via upregulating SIRT3.
Zhang-Jie Yang, Yu-Xin Wang, Shuai Zhao, Na Hu, Dong-Mei Chen, Hui-Ming Ma   +5 more
doaj   +1 more source

Effect of e-cigarette refill liquid on follicular development and estrogen secretion in rats

Tobacco Induced Diseases, 2022
Introduction Electronic cigarettes (e-cigarettes) have recently become popular as an alternative to conventional cigarettes. The aim of this study is to investigate the effects of e-cigarette refill liquid (e-liquid) on follicular development and ...
Tairen Chen, Mengjing Wu, Yuting Dong, Bin Kong, Yufang Cai, Changchun Hei, Kai Wu, Chengjun Zhao, Qing Chang   +8 more
doaj   +1 more source