Results 11 to 20 of about 967,634 (337)

Human umbilical cord-derived mesenchymal stem cells (hUC-MSCs) alleviate excessive autophagy of ovarian granular cells through VEGFA/PI3K/AKT/mTOR pathway in premature ovarian failure rat model

Journal of Ovarian Research, 2023
Background Premature ovarian failure (POF) is one of the leading causes of female infertility and is accompanied by abnormal endocrine, seriously affecting female quality of life.
Wenjie Dai, Hong Yang, Bo Xu, Tiantian He, Ling Liu, Xiaoqian Ma, Jiaxue Ma, Guoqin Yang, Rui Si, Xiuying Pei, Xing Du, Xufeng Fu   +11 more
doaj   +1 more source

Knowledge, attitudes and intention on fertility preservation among breast cancer patients

Scientific Reports, 2023
Breast cancer is the most common cancer in reproductive age women. The aim of this study is to assess the knowledge, attitude and intention on fertility preservation among women diagnosed to have breast cancer.
J. K. Ko, C. Cheung, H. H. Cheng, S. S. Yung, T. Ng, W. Tin, Ho Yan Yuen, Martin H. C. Lam, A. Y. W. Chan, Sara Fung, Vivian Man, A. Kwong, E. Ng   +12 more
semanticscholar   +1 more source

FIGO statement: Fertility preservation

International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics, 2023
Fertility preservation is a growing field in reproductive medicine that may raise ethical questions. Preservation of fertility must be discussed with the patient if gonadotoxic treatment is required, whether in the case of benign or malignant pathology ...
L. Henry, Jonathan S. Berek, I. Diaz, D. Feldberg, Edgar Mocanu, C. Niederberger, Samuel Ohlander, Nikhil Purandare, Z. Rosenwaks, T. Tulandi, Megan Wasson, S. Wilailak, Jaideep Malhotra   +12 more
semanticscholar   +1 more source

Metformin improves polycystic ovary syndrome in mice by inhibiting ovarian ferroptosis

Frontiers in Endocrinology, 2023
Background and objectivePCOS is a common metabolic disorder in women of reproductive age, which pathogenesis is very complex. The role of ferroptosis in PCOS is a novel finding, and the mechanistic studies are not clear. Metformin is a commonly used drug
Qingjie Peng, Xiaojiang Chen, Xiaoxia Liang, Jiahui Ouyang, Qiangqiang Wang, Shuai Ren, Haibo Xie, Chunhong Wang, Yaqun Sun, Xin Wu, Hetao Liu, Changchun Hei, Miao Sun, Qing Chang, Xinrui Liu, Guangyong Li, Guangyong Li, Rui He   +17 more
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The future of fertility preservation for women treated with chemotherapy

Reproduction and Fertility, 2023
Cytotoxic chemotherapies have been a mainstay of cancer treatment but are associated with numerous systemic adverse effects, including impacts on fertility and endocrine health.
L. Alesi, Q. Nguyen, J. Stringer, A. Winship, Karla J. Hutt   +4 more
semanticscholar   +1 more source

For patients with non-obstructive azoospermia, the outcome of testicular sperm extraction correlates with self-esteem, sexual health and the quality of the couple’s relationship

Basic and Clinical Andrology, 2022
Resume Introduction Quelques études concernant l’azoospermie ou les résultats négatifs de l’extraction de sperme testiculaire (TESE) montrent que ces résultats peuvent être liés à la dépression ou aux dysfonctions érectiles.
Marion BENDAYAN, Emine SAIS, Laura ALTER, Khadija FATHALLAH, Monique JAOUL, Pierre Olivier BOSSET, Geoffroy ROBIN, Florence BOITRELLE   +7 more
doaj   +1 more source

Breast Cancer and Fertility Preservation in Young Female Patients: A Systematic Review of the Literature

Clinics and Practice, 2023
Introduction: Breast cancer affects almost 1.5 million women worldwide below the age of 45 years each year. Many of these women will be advised to undergo adjuvant chemotherapy to minimize the risk of death or recurrence of the tumor. For these patients,
Ioannis Boutas, Adamantia Kontogeorgi, Nektarios I Koufopoulos, D. Dimas, Kyparissia Sitara, Sophia N Kalantaridou, Constantine Dimitrakakis   +6 more
semanticscholar   +1 more source

High-Survival Rate After Microinjection of Mouse Oocytes and Early Embryos With mRNA by Combining a Tip Pipette and Piezoelectric-Assisted Micromanipulator

Frontiers in Cell and Developmental Biology, 2021
Utilizing microinjection to introduce biological molecules such as DNA, mRNA, siRNA, and proteins into the cell is well established to study oocyte maturation and early embryo development in vitro. However, microinjection is an empirical technology.
Lei-Ning Chen, Lei-Ning Chen, Xiao-Yan Fan, Xiao-Yan Fan, Yi-Tong Liu, Shao-Qing Chen, Feng-Yun Xie, Feng-Yun Xie, Li Zeng, Juan Wen, Jin Li, Jun-Yu Ma, Jun-Yu Ma, Xiang-Hong Ou, Xiang-Hong Ou, Shi-Ming Luo, Shi-Ming Luo, Lei Guo, Lei Guo   +18 more
doaj   +1 more source

Fertility Preservation in Young Women With Breast Cancer: A Review

Journal of Breast Cancer, 2023
Fertility preservation is a major concern in young patients diagnosed with breast cancer and planning to receive multimodality treatment, including gonadotoxic chemotherapy with or without age-related decline through long-term endocrine therapy.
Y. Hong, Changhee Park, H. Paik, Kyung-Hun Lee, J. R. Lee, W. Han, Seho Park, Seockhoon Chung, Hee Jeong Kim   +8 more
semanticscholar   +1 more source

Cancer Treatment-Related Ovarian Dysfunction in Women of Childbearing Potential: Management and Fertility Preservation Options

Journal of Clinical Oncology, 2023
PURPOSE To review the complex concerns of oncofertility created through increased cancer survivorship and the long-term effects of cancer treatment in young adults.
A. C. Reynolds, L. McKenzie
semanticscholar   +1 more source