Results 181 to 190 of about 46,526 (241)

Single‐cell sequencing reveals potential novel insights into appendage‐patterning and joint‐development in a spider

Developmental Dynamics, EarlyView.
Abstract Background Jointed appendages represent one of the key innovations of arthropods, and thus understanding the development and evolution of these structures is important for the understanding of the evolutionary success of Arthropoda. In this paper, we analyze a cell cluster that was identified in a previous single‐cell sequencing (SCS ...
Brenda I. Medina‐Jiménez, Graham E. Budd, Ralf Janssen   +2 more
wiley   +1 more source

Detection of 4977-bp deletion of mitochondrial DNA in in vitro fertilization failure women: A case-control study. [PDF]

Int J Reprod Biomed, 2018
Mirabutalebi SH, Karami N, Ashrafzadeh HR, Akhvansales Z, Tavakoli M, Ghasemi N.   +5 more
europepmc   +1 more source

The β integrin modulates serotonin sensitivity via NPxY motifs to regulate egg laying and mechanosensation behaviors in Caenorhabditis elegans

Developmental Dynamics, EarlyView.
Abstract Background Integrin is an αβ heterodimeric receptor to the extracellular matrix; its binding to the matrix recruits focal adhesions to two NPxY motifs, the tyrosine phosphorylation sites in the cytoplasmic domain. Studies found that replacing tyrosines (Y) with phenylalanines (F) in the motif of β1 integrin displayed little developmental or ...
Josh Haram Bumm, Daniel Dogeon Lee, Zhongqiang Qiu, Angela Haeun Choi, Meghana Kolluri, Michael J. Olsen, Lianzijun Wang, Myeongwoo Lee   +7 more
wiley   +1 more source

The role of Rho GTPases in facial morphogenesis

Developmental Dynamics, EarlyView.
The role of small GTPases, RHOA, RAC1, and CDC42 and pathway mediators is reviewed in the context of embryonic facial development. Lip fusion requires cytoskeletal remodeling during morphogenesis of the facial processes and during lip fusion. Fnm, frontonasal mass; lnp, lateral nasal process; mnp, medial nasal process; mxp, maxillary process; np, nasal
Isra Ibrahim, Joy M. Richman
wiley   +1 more source

Fhod3 in zebrafish supports myofibril stability during growth of embryonic skeletal muscle

Developmental Dynamics, EarlyView.
Abstract Background Actin filament organization in cardiomyocytes critically depends on the formin Fhod3, but a role for Fhod3 in skeletal muscle development has not yet been described. Results We demonstrate here that in zebrafish mutated for one of two fhod3 paralog genes, fhod3a, skeletal muscle of the trunk appears normal through 2 days post ...
Aubrie Russell, Tracy Eng, Jeffrey D. Amack, David Pruyne   +3 more
wiley   +1 more source

Bridging maternal effects and epitranscriptomics: A novel perspective in developmental biology

Developmental Dynamics, EarlyView.
Abstract Maternal effects, encompassing both genetic (maternally expressed gene products) and non‐genetic (maternal state) influences, are powerful determinants of offspring phenotype, yet their RNA‐level mechanisms remain incompletely resolved. In parallel, epitranscriptomics, an emerging field centered on chemical modifications to RNA, has revealed ...
Ehsan Pashay Ahi
wiley   +1 more source

Zebrafish inversin mutants develop scoliosis in the absence of laterality defects

Developmental Dynamics, EarlyView.
Abstract Background Human mutations in INVERSIN are associated with nephronophthisis, variable penetrance of situs inversus and congenital heart disease. Inversin has been shown to localize to cilia and many of the patient phenotypes are attributed to disrupted cilia function.
Christopher J. Derrick, Lorraine Eley, Deborah J. Henderson, Bill Chaudhry   +3 more
wiley   +1 more source

An accessible microfluidic perfusion platform for time‐restricted control of zebrafish embryonic patterning

Developmental Dynamics, EarlyView.
Abstract Understanding the dynamic nature of developmental networks requires live imaging techniques capable of capturing real‐time developmental processes in wild‐type and mutant embryos as they are exposed to pharmacological perturbations. A peculiar developmental patterning process in early vertebrate embryos is the sequential segmentation of ...
Mohammed Nakhuda, M. Fethullah Simsek
wiley   +1 more source

Comparative Analysis of Metal Preloading Technologies in Batteries and Capacitors

EcoEnergy, EarlyView.
Metal preloading strategies play an important role in efficient batteries and hybrid capacitors to compensate for the consumed metals at the first discharge. This article reviews recent progress in preloading technologies in lithium‐ion and other metal‐ion systems.
Xuexue Pan, Yu Zhang, Zhazira Supiyeva, Qamar Abbas   +3 more
wiley   +1 more source

Oxygen‐Vacancy‐Engineered Ru–V Dual Sites in InVO4 for Synergistic Photocatalytic N2 Activation and Reactive Hydrogen Supply

EcoEnergy, EarlyView.
This study developed a catalyst composed of Ru nanoparticles directionally anchored at the oxygen vacancies of indium vanadate. Oxygen vacancy not only forms unsaturated V sites but also serves as an anchoring site for Ru nanoparticles, establishing a stable Ru‐V coordination structure through electronic metal–support interactions.
Qianyu Chu, Guangmin Ren, Xiaoyue Chen, Xiangchao Meng, Zizhen Li   +4 more
wiley   +1 more source