Results 31 to 40 of about 46,526 (241)

Failed Fertilization in ART: What are the Causes and Methods to Improve Fertilization

open access: yesFertility & Reproduction, 2023
Introduction of clinical ICSI made a revolution in achieving higher fertilization in ART programs. However, ICSI does not completely eliminate the risk of fertilization failure as total fertilization failure (TFF) occurs in 1-3% of ICSI cycles. TFF leads
Satish Kumar Adiga
doaj   +1 more source

Fertilization failure and gamete health Is there a link

open access: yesFrontiers in Bioscience, 2017
Fertilization is a hallmark event of sexual reproduction marked by the fusion of male and female gamete to form zygote. It is a highly complex, yet a robust process that is intricately regulated by various signalling molecules. A healthy fertilization is determined by the quality of zygote which is contingent on the health of egg and sperm.
Snehil, Budhwar   +3 more
openaire   +2 more sources

Prediction of Fertilization Disorders in the In Vitro Fertilization/Intracytoplasmic Sperm Injection: A Retrospective Study of 106,728 Treatment Cycles

open access: yesFrontiers in Endocrinology, 2022
PurposeThis study aimed to develop a risk prediction of fertilization disorders during the in vitro fertilization/intracytoplasmic sperm injection (IVF/ICSI).MethodsA retrospective study was performed with 106,728 fresh embryo IVF/ICSI cycles from 2009 ...
Tian Tian   +39 more
doaj   +1 more source

Chronic endometritis in In-Vitro fertilization failure patients [PDF]

open access: yesGlobal Journal of Fertility and Research, 2020
Introduction: Chronic endometritis (CE) is a common cause of infertility in asymptomatic patients and its diagnosis and treatments improved assisted reproduction technique outcome in most of the specialized centers. Diagnosis of CE in endometrial biopsy by Hematoxylin and Eosin (H&E) stain is hard to identify chronic inflammatory cells from the ...
Afaf T Elnashar, Mohamed Sabry
openaire   +2 more sources

Successful rescue activation of unfertilized oocytes with calcium ionophore (A23187) in a case of recurrent ICSI fertilization failure: A case report

open access: yesAsian Pacific Journal of Reproduction
Rationale: This case report describes a couple with recurrent fertilization failure despite undergoing multiple cycles of intracytoplasmic sperm injection (ICSI).
Akash More   +4 more
doaj   +1 more source

Should rescue ICSI be re-evaluated considering the deferred transfer of cryopreserved embryos in in-vitro fertilization cycles? A systematic review and meta-analysis

open access: yesReproductive Biology and Endocrinology, 2021
Background Total fertilization failure represents a particularly frustrating condition for couples undergoing in vitro fertilization. With the aim of reducing the occurrence of total fertilization failure, intracytoplasmic sperm injection (ICSI) has ...
Alessio Paffoni   +5 more
doaj   +1 more source

ART failure: oocyte contributions to unsuccessful fertilization [PDF]

open access: yesHuman Reproduction Update, 2008
The complexity of fertilization failure during assisted reproductive technologies (ART) is often under-appreciated, as this failure can occur at any number of essential mechanistic and cellular events. Importantly, successful fertilization is heavily dependent upon inherent qualities of the oocytes, and thus reliant upon fidelity of oocyte maturation ...
Jason E, Swain, Thomas B, Pool
openaire   +2 more sources

THE FAILURE OF THE COPPER IUD TO INHIBIT FERTILIZATION IN THE RABBIT [PDF]

open access: yesReproduction, 1970
The effect of intra-uterine devices (IUDs) in rabbits is variable. Depending on size, intra-uterine threads and plastic IUDs cause incomplete and localized reductions in fertility (Brown & Foote, 1966; Marston & Chang, 1969). Recently, the use of copper coils in rabbits and copper wire (in combination with plastic `T' devices) in humans has ...
J P, Polidoro, D L, Black
openaire   +2 more sources

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

Distinct germ-line genetic mutation patterns correlate with reproductive outcomes in ICSI patients: a pilot study

open access: yesFrontiers in Genetics
BackgroundInfertility affects approximately 15% of couples worldwide, with male factors accounting for nearly 50% of cases. Intracytoplasmic sperm injection (ICSI) has become the standard treatment for male factor infertility, but outcomes vary ...
Ting Jiang   +6 more
doaj   +1 more source

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